Innate effector cells in angiogenesis and lymphangiogenesis.

[1]  G. Marone,et al.  Human mast cells and basophils—How are they similar how are they different? , 2018, Immunological reviews.

[2]  G. Marone,et al.  Eosinophils: The unsung heroes in cancer? , 2018, Oncoimmunology.

[3]  Evan W. Newell,et al.  Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2 , 2017, Immunity.

[4]  C. Bokemeyer,et al.  Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B , 2017, Nature Communications.

[5]  T. Petrova,et al.  Microenvironmental regulation of tumour angiogenesis , 2017, Nature Reviews Cancer.

[6]  S. Gordon,et al.  Tissue macrophages: heterogeneity and functions , 2017, BMC Biology.

[7]  Michael B. Stadler,et al.  An Immune Atlas of Clear Cell Renal Cell Carcinoma , 2017, Cell.

[8]  K. Alitalo,et al.  VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling , 2017, Circulation research.

[9]  F. Mattei,et al.  IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils , 2017, Oncoimmunology.

[10]  F. Granata,et al.  Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils , 2017, Front. Immunol..

[11]  F. Granata,et al.  Are Mast Cells MASTers in Cancer? , 2017, Front. Immunol..

[12]  F. Stossi,et al.  Mutual Regulation of Tumour Vessel Normalization and Immunostimulatory Reprogramming , 2017, Nature.

[13]  I. Xenarios,et al.  TIE-2 expressing monocytes in human cancers , 2017, Oncoimmunology.

[14]  A. Giobbie-Hurder,et al.  Angiopoietin-2 as a Biomarker and Target for Immune Checkpoint Therapy , 2016, Cancer Immunology Research.

[15]  Emma Gordon,et al.  Mechanisms and regulation of endothelial VEGF receptor signalling , 2016, Nature Reviews Molecular Cell Biology.

[16]  C. Garlanda,et al.  Occurrence and significance of tumor‐associated neutrophils in patients with colorectal cancer , 2016, International journal of cancer.

[17]  R. Förster,et al.  Chemokines and Chemokine Receptors in Lymphoid Tissue Dynamics. , 2016, Annual review of immunology.

[18]  F. Granata,et al.  Mast cells and basophils in inflammatory and tumor angiogenesis and lymphangiogenesis. , 2016, European journal of pharmacology.

[19]  M. Triggiani,et al.  Human lung‐resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors , 2016, Journal of leukocyte biology.

[20]  M. Reni,et al.  Basophil Recruitment into Tumor-Draining Lymph Nodes Correlates with Th2 Inflammation and Reduced Survival in Pancreatic Cancer Patients. , 2016, Cancer research.

[21]  J. Joyce,et al.  Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response , 2015, Nature Reviews Cancer.

[22]  F. Granata,et al.  Angiogenesis and lymphangiogenesis in inflammatory skin disorders. , 2015, Journal of the American Academy of Dermatology.

[23]  Y. Yoon,et al.  Generation of pure lymphatic endothelial cells from human pluripotent stem cells and their therapeutic effects on wound repair , 2015, Scientific Reports.

[24]  G. Hämmerling,et al.  Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8+ T cells , 2015, Nature Immunology.

[25]  M. Cassatella,et al.  Neutrophil-Derived Cytokines: Facts Beyond Expression , 2014, Front. Immunol..

[26]  G. Marone,et al.  The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis , 2014, Oncogene.

[27]  K. Alitalo,et al.  Vascular endothelial growth factor-B in physiology and disease. , 2014, Physiological reviews.

[28]  F. Ginhoux,et al.  Monocytes and macrophages: developmental pathways and tissue homeostasis , 2014, Nature Reviews Immunology.

[29]  Michael Detmar,et al.  Mechanisms of lymphatic metastasis. , 2014, The Journal of clinical investigation.

[30]  G. Koh,et al.  Inflammation-associated lymphangiogenesis: a double-edged sword? , 2014, The Journal of clinical investigation.

[31]  K. Alitalo,et al.  Lymphangiogenic factors, mechanisms, and applications. , 2014, The Journal of clinical investigation.

[32]  C. Garlanda,et al.  Tumor associated macrophages and neutrophils in cancer. , 2013, Immunobiology.

[33]  Sonja Loges,et al.  Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer. , 2013, The Journal of clinical investigation.

[34]  S. Staibano,et al.  Helicobacter Pylori HP(2–20) Induces Eosinophil Activation and Accumulation in Superficial Gastric Mucosa and Stimulates VEGF-α and TGF-β Release by Interacting with Formyl-Peptide Receptors , 2013, International Journal of Immunopathology and Pharmacology.

[35]  P. Saharinen,et al.  Angiopoietin signaling in the vasculature. , 2013, Experimental cell research.

[36]  H. Nagano,et al.  TIE2‐expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis , 2013, Hepatology.

[37]  A. Sica,et al.  Macrophage plasticity and polarization in tissue repair and remodelling , 2013, The Journal of pathology.

[38]  Fan Zhang,et al.  Complicated life, complicated VEGF-B. , 2012, Trends in molecular medicine.

[39]  Holger Gerhardt,et al.  Basic and Therapeutic Aspects of Angiogenesis , 2011, Cell.

[40]  L. Naldini,et al.  Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. , 2011, Cancer cell.

[41]  J. Waltenberger,et al.  VEGF-A-induced chemotaxis of CD16+ monocytes is decreased secondary to lower VEGFR-1 expression. , 2011, Atherosclerosis.

[42]  K. Plate,et al.  Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion , 2011, The Journal of Immunology.

[43]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[44]  S. Véronneau,et al.  Cysteinyl‐leukotrienes induce vascular endothelial growth factor production in human monocytes and bronchial smooth muscle cells , 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[45]  M. Santoro,et al.  Mast cells have a protumorigenic role in human thyroid cancer , 2010, Oncogene.

[46]  P. Carmeliet,et al.  Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation , 2010, Circulation.

[47]  M. Gavala,et al.  Extracellular ATP May Contribute to Tissue Repair by Rapidly Stimulating Purinergic Receptor X7-Dependent Vascular Endothelial Growth Factor Release from Primary Human Monocytes , 2010, The Journal of Immunology.

[48]  Massimo Triggiani,et al.  Production of Vascular Endothelial Growth Factors from Human Lung Macrophages Induced by Group IIA and Group X Secreted Phospholipases A2 , 2010, The Journal of Immunology.

[49]  S. Stone-Elander,et al.  Vascular endothelial growth factor B controls endothelial fatty acid uptake , 2010, Nature.

[50]  Z. Werb,et al.  Matrix Metalloproteinases: Regulators of the Tumor Microenvironment , 2010, Cell.

[51]  Erika Peterson,et al.  IL-33 augments substance P–induced VEGF secretion from human mast cells and is increased in psoriatic skin , 2010, Proceedings of the National Academy of Sciences.

[52]  P. Howarth,et al.  Osteopontin is expressed and functional in human eosinophils , 2010, Allergy.

[53]  D. Carr,et al.  VEGF-A expression by HSV-1–infected cells drives corneal lymphangiogenesis , 2009, The Journal of experimental medicine.

[54]  G. Cheng,et al.  Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN. , 2009, Cancer cell.

[55]  M. Triggiani,et al.  Lung mast cells are a source of secreted phospholipases A2. , 2009, The Journal of allergy and clinical immunology.

[56]  M. Triggiani,et al.  Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects. , 2009, The Journal of allergy and clinical immunology.

[57]  Christian Fischer,et al.  FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? , 2008, Nature Reviews Cancer.

[58]  Seppo Ylä-Herttuala,et al.  Overexpression of Vascular Endothelial Growth Factor-B in Mouse Heart Alters Cardiac Lipid Metabolism and Induces Myocardial Hypertrophy , 2008, Circulation research.

[59]  M. Shibuya,et al.  Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting , 2007, The Journal of experimental medicine.

[60]  D. Ribatti,et al.  Expression and Functions of the Vascular Endothelial Growth Factors and Their Receptors in Human Basophils1 , 2006, The Journal of Immunology.

[61]  Christopher Chiu,et al.  Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis , 2006, Proceedings of the National Academy of Sciences.

[62]  Lena Claesson-Welsh,et al.  Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. , 2006, Experimental cell research.

[63]  D. Kerjaschki,et al.  Lymphatic endothelial progenitor cells contribute to de novo lymphangiogenesis in human renal transplants , 2006, Nature Medicine.

[64]  Peter Carmeliet,et al.  Angiogenesis in life, disease and medicine , 2005, Nature.

[65]  Tatiana V. Petrova,et al.  Lymphangiogenesis in development and human disease , 2005, Nature.

[66]  Luigi Naldini,et al.  Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. , 2005, Cancer cell.

[67]  K. Alitalo,et al.  Angiopoietin-1 promotes lymphatic sprouting and hyperplasia. , 2005, Blood.

[68]  Satoshi Hirakawa,et al.  VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis , 2005, The Journal of experimental medicine.

[69]  Raja' M. Abdel-Majid,et al.  Prostaglandin E2 Induces Degranulation-Independent Production of Vascular Endothelial Growth Factor by Human Mast Cells1 , 2004, The Journal of Immunology.

[70]  C. Marsh,et al.  M-CSF Induces Vascular Endothelial Growth Factor Production and Angiogenic Activity From Human Monocytes 1 , 2003, The Journal of Immunology.

[71]  K. Alitalo,et al.  The Angiogenic and Lymphangiogenic Factor Vascular Endothelial Growth Factor-D Exhibits a Paracrine Mode of Action in Cancer , 2002, Growth factors.

[72]  R. Hershkoviz,et al.  Human Mast Cells Release Metalloproteinase-9 on Contact with Activated T Cells: Juxtacrine Regulation by TNF-α1 , 2001, The Journal of Immunology.

[73]  M. Karkkainen,et al.  Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. , 2001, Cancer research.

[74]  Steven A. Stacker,et al.  VEGF-D promotes the metastatic spread of tumor cells via the lymphatics , 2001, Nature Medicine.

[75]  N. Aoike,et al.  Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. , 2001, The Journal of allergy and clinical immunology.

[76]  R. Moqbel,et al.  Human eosinophils release matrix metalloproteinase-9 on stimulation with TNF-alpha. , 1999, The Journal of allergy and clinical immunology.

[77]  B. Terman,et al.  Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization , 1999, Oncogene.

[78]  H. Dvorak,et al.  Mast Cells Can Secrete Vascular Permeability Factor/ Vascular Endothelial Cell Growth Factor and Exhibit Enhanced Release after Immunoglobulin E–dependent Upregulation of Fcε Receptor I Expression , 1998, The Journal of experimental medicine.

[79]  H. Kita,et al.  Migration of eosinophils through basement membrane components in vitro: role of matrix metalloproteinase-9. , 1997, American journal of respiratory cell and molecular biology.

[80]  T. Horiuchi,et al.  Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5. , 1997, American journal of respiratory cell and molecular biology.

[81]  G. Breier,et al.  The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities , 1996, The Journal of Biological Chemistry.

[82]  A. Mantovani,et al.  Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. , 1996, Blood.

[83]  K. Alitalo,et al.  A novel vascular endothelial growth factor, VEGF‐C, is a ligand for the Flt4 (VEGFR‐3) and KDR (VEGFR‐2) receptor tyrosine kinases. , 1996, The EMBO journal.

[84]  Konrad M. Hartung,et al.  IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma. , 1995, Journal of immunology.

[85]  G. Viglietto,et al.  Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14. , 1993, Oncogene.

[86]  J. Winer,et al.  Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. , 1992, The Journal of biological chemistry.

[87]  G. Viglietto,et al.  Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[88]  H. Dvorak,et al.  Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. , 1983, Science.

[89]  J. Folkman.  Tumor angiogenesis: therapeutic implications. , 1971, The New England journal of medicine.

[90]  A. Mantovani,et al.  Phagocytes as Corrupted Policemen in Cancer-Related Inflammation. , 2015, Advances in cancer research.

[91]  S. Sozzani,et al.  Angiogenic and antiangiogenic chemokines. , 2014, Chemical immunology and allergy.

[92]  F. Granata,et al.  Angiogenesis, lymphangiogenesis and clinical implications. Preface. , 2014, Chemical immunology and allergy.

[93]  I. Zachary,et al.  Neuropilins: role in signalling, angiogenesis and disease. , 2014, Chemical immunology and allergy.

[94]  F. Levi-Schaffer,et al.  Roles of eosinophils in the modulation of angiogenesis. , 2014, Chemical immunology and allergy.

[95]  K. Alitalo,et al.  A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. , 1996, The EMBO journal.