Identification of suitable fundus images using automated quality assessment methods

Abstract. Retinal image quality assessment (IQA) is a crucial process for automated retinal image analysis systems to obtain an accurate and successful diagnosis of retinal diseases. Consequently, the first step in a good retinal image analysis system is measuring the quality of the input image. We present an approach for finding medically suitable retinal images for retinal diagnosis. We used a three-class grading system that consists of good, bad, and outlier classes. We created a retinal image quality dataset with a total of 216 consecutive images called the Diabetic Retinopathy Image Database. We identified the suitable images within the good images for automatic retinal image analysis systems using a novel method. Subsequently, we evaluated our retinal image suitability approach using the Digital Retinal Images for Vessel Extraction and Standard Diabetic Retinopathy Database Calibration level 1 public datasets. The results were measured through the F1 metric, which is a harmonic mean of precision and recall metrics. The highest F1 scores of the IQA tests were 99.60%, 96.50%, and 85.00% for good, bad, and outlier classes, respectively. Additionally, the accuracy of our suitable image detection approach was 98.08%. Our approach can be integrated into any automatic retinal analysis system with sufficient performance scores.

[1]  Pat Morin,et al.  Output-Sensitive Algorithms for Computing Nearest-Neighbour Decision Boundaries , 2003, WADS.

[2]  K. W. Tobin,et al.  Elliptical local vessel density: A fast and robust quality metric for retinal images , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[3]  Whoi-Yul Kim,et al.  A novel approach to the fast computation of Zernike moments , 2006, Pattern Recognit..

[4]  Max A. Viergever,et al.  Ridge-based vessel segmentation in color images of the retina , 2004, IEEE Transactions on Medical Imaging.

[5]  Robert M. Haralick,et al.  Textural Features for Image Classification , 1973, IEEE Trans. Syst. Man Cybern..

[6]  Jian Yang,et al.  Why can LDA be performed in PCA transformed space? , 2003, Pattern Recognit..

[7]  Rangaraj M. Rangayyan,et al.  Using relevance feedback to reduce the semantic gap in content-based image retrieval of mammographic masses , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[8]  Jack Sklansky,et al.  A note on genetic algorithms for large-scale feature selection , 1989, Pattern Recognit. Lett..

[9]  Harry Zhang,et al.  The Optimality of Naive Bayes , 2004, FLAIRS.

[10]  Chee Sun Won Feature Extraction and Evaluation Using Edge Histogram Descriptor in MPEG-7 , 2004, PCM.

[11]  Asoke K. Nandi,et al.  Automated localisation of retinal optic disk using Hough transform , 2008, 2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[12]  Corinna Cortes,et al.  Support-Vector Networks , 1995, Machine Learning.

[13]  Bin Zheng,et al.  Computer-Aided Diagnosis in Mammography Using Content-Based Image Retrieval Approaches: Current Status and Future Perspectives , 2009, Algorithms.

[14]  B. Scholkopf,et al.  Fisher discriminant analysis with kernels , 1999, Neural Networks for Signal Processing IX: Proceedings of the 1999 IEEE Signal Processing Society Workshop (Cat. No.98TH8468).

[15]  C. Sinthanayothin,et al.  Automated localisation of the optic disc, fovea, and retinal blood vessels from digital colour fundus images , 1999, The British journal of ophthalmology.

[16]  Pat Morin,et al.  Output-Sensitive Algorithms for Computing Nearest-Neighbour Decision Boundaries , 2005, Discret. Comput. Geom..

[17]  A. Bainbridge-Smith,et al.  Automated Assessment of Diabetic Retinal Image Quality Based on Blood Vessel Detection , 2007 .

[18]  Chee Sun Won,et al.  Efficient use of local edge histogram descriptor , 2000, MULTIMEDIA '00.

[19]  B. S. Manjunath,et al.  Color and texture descriptors , 2001, IEEE Trans. Circuits Syst. Video Technol..

[20]  U. Rajendra Acharya,et al.  Automated Diagnosis of Glaucoma Using Digital Fundus Images , 2009, Journal of Medical Systems.

[21]  J. Olson,et al.  Automated assessment of diabetic retinal image quality based on clarity and field definition. , 2006, Investigative ophthalmology & visual science.

[22]  H. K. D. H. Bhadeshia,et al.  Neural Networks in Materials Science , 1999 .

[23]  Joachim Hornegger,et al.  Automated quality assessment of retinal fundus photos , 2010, International Journal of Computer Assisted Radiology and Surgery.

[24]  Uğur Şevik,et al.  Automatic segmentation of age-related macular degeneration in retinal fundus images , 2008, Comput. Biol. Medicine.

[25]  Frédéric Zana,et al.  Segmentation of vessel-like patterns using mathematical morphology and curvature evaluation , 2001, IEEE Trans. Image Process..

[26]  Langis Gagnon,et al.  Automatic visual quality assessment in optical fundus images , 2001 .

[27]  Antoine Geissbühler,et al.  A Review of Content{Based Image Retrieval Systems in Medical Applications { Clinical Bene(cid:12)ts and Future Directions , 2022 .

[28]  Cemal Köse,et al.  Simple methods for segmentation and measurement of diabetic retinopathy lesions in retinal fundus images , 2012, Comput. Methods Programs Biomed..

[29]  Yiming Wang,et al.  Automatic retinal image quality assessment and enhancement , 1999, Medical Imaging.

[30]  Yiming Wang,et al.  Illumination normalization of retinal images using sampling and interpolation , 2001, SPIE Medical Imaging.

[31]  Tomi Kauppi,et al.  Eye Fundus Image Analysis for Automatic Detection of Diabetic Retinopathy , 2010 .

[32]  Josef Kittler,et al.  Floating search methods in feature selection , 1994, Pattern Recognit. Lett..

[33]  Ali M. Reza,et al.  Realization of the Contrast Limited Adaptive Histogram Equalization (CLAHE) for Real-Time Image Enhancement , 2004, J. VLSI Signal Process..

[34]  Bram van Ginneken,et al.  Image structure clustering for image quality verification of color retina images in diabetic retinopathy screening , 2006, Medical Image Anal..

[35]  U. Acharya,et al.  Automatic identification of diabetic maculopathy stages using fundus images , 2009, Journal of medical engineering & technology.