Pemphigus is a rare disease that causes blistering of the skin and mucous membranes. The Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) and Pemphigus Disease Area Index (PDAI) are two new scoring systems to measure pemphigus activity, such as the extent of the symptoms, patient discomfort, or skin damage. However, neither of the scores include cut-off values, meaning an explanation of whether each score shows the extent of the disease is moderate, significant or extensive. The aim of this study was to propose cut-off values that could define pemphigus as moderate, significant or extensive. It involved 96 patients treated in 31 French, German, Italian, Swiss, Croatian and Australian dermatology departments. Their ABSIS and PDAI scores were correlated, along with two other scoring systems used for skin diseases more generally, to arrive at cut-off values. The authors conclude that identifying three subgroups of moderate, significant and extensive pemphigus should help physicians to classify and manage patients more effectively. Furthermore, this should allow for direct comparisons between treatment regimens in future studies.