Development of a modified micronucleus assay in vitro for detection of aneugenic effects.

[1]  S. Williams,et al.  Kinetochore analysis of micronuclei allows insights into the actions of colcemid and mitomycin C. , 1991, Mutation research.

[2]  A. Antoccia,et al.  In vitro micronucleus test with kinetochore staining: evaluation of test performance. , 1991, Mutagenesis.

[3]  D. Eastmond,et al.  Kinetochore localization in micronucleated cytokinesis-blocked Chinese hamster ovary cells: a new and rapid assay for identifying aneuploidy-inducing agents. , 1989, Mutation research.

[4]  L. Migliore,et al.  The human lymphocyte micronucleus assay: a comparison between whole-blood and separated-lymphocyte cultures. , 1989, Mutation research.

[5]  M. Nüsse,et al.  Induction of kinetochore positive and negative micronuclei in V79 cells by the alkylating agent diethylsulphate. , 1989, Mutagenesis.

[6]  A. De Sario,et al.  Aneuploidy assays on interphase nuclei by means of in situ hybridization with DNA probes. , 1989, Mutagenesis.

[7]  M. Fenech,et al.  Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss. , 1989, Mutagenesis.

[8]  C. Tanzarella,et al.  Immunofluorescent staining of kinetochores in micronuclei: a new assay for the detection of aneuploidy. , 1988, Mutation research.

[9]  E. Parry,et al.  The effects of benzodiazepines upon the fidelity of mitotic cell division in cultured Chinese hamster cells. , 1987, Mutation research.

[10]  I. Larripa,et al.  Mutagenic bioassay of certain pharmacological drugs. I. Thiabendazole (TBZ). , 1987, Mutation research.

[11]  C Ramel,et al.  Deployment of short-term assays for the detection of carcinogens; genetic and molecular considerations. , 1986, Mutation research.

[12]  B. Högstedt,et al.  The size of micronuclei in human lymphocytes varies according to inducing agent used. , 1985, Mutation research.

[13]  G. Obe,et al.  Mutagenicity of methyl 2-benzimidazolecarbamate, diethylstilbestrol and estradiol: structural chromosomal aberrations, sister-chromatid exchanges, C-mitoses, polyploidies and micronuclei. , 1985, Mutation research.

[14]  I. Taylor,et al.  Clinical and biological significance of aneuploidy in human tumours. , 1984, Journal of clinical pathology.

[15]  B. Högstedt Micronuclei in lymphocytes with preserved cytoplasm. A method for assessment of cytogenetic damage in man. , 1984, Mutation research.

[16]  T. Hsu,et al.  Aneuploidy induction by mitotic arrestants. Effects of diazepam on diploid Chinese hamster cells. , 1983, Mutation research.

[17]  L. Andersson,et al.  Diazepam induces mitotic arrest at prometaphase by inhibiting centriolar separation , 1981, Nature.

[18]  K. Sankaranarayanan The role of non-disjunction in aneuploidy in man. An overview. , 1979, Mutation research.

[19]  M. De Brabander,et al.  A new culture model facilitating rapid quantitative testing of mitotic spindle inhibition in mammalian cells. , 1976, Journal of the National Cancer Institute.

[20]  B. Ames,et al.  Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. , 1975, Mutation research.

[21]  L. Larizza,et al.  Griseofulvin: a potential agent of chromosomal segregation in cultured cells. , 1974, Mutation research.

[22]  L. Migliore,et al.  Evaluation of twelve potential aneuploidogenic chemicals by the in vitro human lymphocyte micronucleus assay. , 1991, Toxicology in vitro : an international journal published in association with BIBRA.

[23]  J. Parry,et al.  A study of the induction of aneuploidy and chromosome aberrations after diazepam, medazepam, midazolam and bromazepam treatment. , 1988, Mutagenesis.

[24]  L. Migliore,et al.  Cytogenetic damage induced in human lymphocytes by adriamycin and vincristine: A comparison between micronucleus and chromosomal aberration assays. , 1987, Toxicology in Vitro.

[25]  J. Barrett,et al.  Chemically induced aneuploidy in mammalian cells: mechanisms and biological significance in cancer. , 1986, Environmental mutagenesis.

[26]  S. Madle,et al.  Comparison of S9 mix and hepatocytes as external metabolizing systems in mammalian cell cultures: cytogenetic effects of 7,12-dimethylbenzanthracene and aflatoxin B1. , 1986, Environmental mutagenesis.

[27]  B. Brinkley,et al.  Chemical probes and possible targets for the induction of aneuploidy. , 1985, Basic life sciences.

[28]  T. Hsu,et al.  Aneuploidy by mitotic arrestants. Effects of diazepam on diploid Chinese hamster cells , 1983 .