Biopsy‐proved Alzheimer disease presenting as a right parietal lobe syndrome

A progressive right parietal lobe disorder charcterized by astereognosis and pseudoathetosis developed in a 57‐year‐old woman. Two years later, the patient began to show signs of intellectual deterioration. Biopsy of the right frontal lobe revealed numerous plaques and tangles. The patient's right parietal lobe dysfunction was probably the first manifestation of Alzhemer disease. On rare occasions, Alzhemier disease can present as a focal syndrome with findings referable to a localized area of maximal involvement.

[1]  L. Heston,et al.  Alzheimer's disease. A family study. , 1966, Archives of neurology.

[2]  A. Faden,et al.  Myoclonus in Alzheimer disease. A confusing sign. , 1976, Archives of neurology.

[3]  A. Wechsler Presenile dementia presenting as aphasia. , 1977, Journal of neurology, neurosurgery, and psychiatry.

[4]  M. Sim,et al.  ALZHEIMER'S DISEASE: ITS NATURAL HISTORY AND DIFFERENTIAL DIAGNOSIS , 1962, The Journal of nervous and mental disease.

[5]  E. Liston The Clinical Phenomenology of Presenile Dementia A Critical Review of the Literature , 1979, The Journal of nervous and mental disease.