Classification Accuracy of Transcranial Magnetic Stimulation for the Diagnosis of Neurodegenerative Dementias

Transcranial magnetic stimulation (TMS) has been suggested as a reliable, noninvasive, and inexpensive tool for the diagnosis of neurodegenerative dementias. In this study, we assessed the classification performance of TMS parameters in the differential diagnosis of common neurodegenerative disorders, including Alzheimer disease (AD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD).

[1]  S. Cappa,et al.  Incidence of frontotemporal lobar degeneration in Italy , 2019, Neurology.

[2]  B. Borroni,et al.  Clinical and biomarker changes in presymptomatic genetic frontotemporal dementia , 2019, Neurobiology of Aging.

[3]  B. Borroni,et al.  Toward a Glutamate Hypothesis of Frontotemporal Dementia , 2019, Front. Neurosci..

[4]  Dan J Stein,et al.  Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 , 2019, The Lancet Neurology.

[5]  Alessandra Flammini,et al.  Diagnosis of Mild Cognitive Impairment Due to Alzheimer's Disease with Transcranial Magnetic Stimulation. , 2018, Journal of Alzheimer's disease : JAD.

[6]  N. Mercuri,et al.  Transcranial magnetic stimulation predicts cognitive decline in patients with Alzheimer’s disease , 2018, Journal of Neurology, Neurosurgery, and Psychiatry.

[7]  V. Lazzaro.  Emergence of neurophysiological biomarkers of Alzheimer disease. , 2018 .

[8]  Kevin F. Bieniek,et al.  Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study , 2018, The Lancet Neurology.

[9]  B. Borroni,et al.  Neuroanatomical Correlates of Transcranial Magnetic Stimulation in Presymptomatic Granulin Mutation Carriers , 2018, Brain Topography.

[10]  T. Uchihara,et al.  Reader response: Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB consortium , 2018, Neurology.

[11]  J. Rowe,et al.  Neurotransmitter deficits from frontotemporal lobar degeneration , 2018, Brain : a journal of neurology.

[12]  B. Borroni,et al.  Discrimination of atypical parkinsonisms with transcranial magnetic stimulation , 2017, Brain Stimulation.

[13]  Alessandra Flammini,et al.  Transcranial magnetic stimulation distinguishes Alzheimer disease from frontotemporal dementia , 2017, Neurology.

[14]  C. Jack,et al.  Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers , 2017, The Lancet Neurology.

[15]  Alan J. Thomas,et al.  Diagnosis and management of dementia with Lewy bodies , 2017, Neurology.

[16]  P. Pasqualetti,et al.  Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment: The Incremental Diagnostic Value of Amyloid PET With [18F]-Florbetapir (INDIA-FBP) Study. , 2016, JAMA neurology.

[17]  B. Borroni,et al.  Impaired long‐term potentiation–like cortical plasticity in presymptomatic genetic frontotemporal dementia , 2016, Annals of neurology.

[18]  Alan J. Thomas,et al.  Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations , 2016, Acta neuropathologica communications.

[19]  A. Strafella,et al.  TMS and drugs revisited 2014 , 2015, Clinical Neurophysiology.

[20]  M. Prince,et al.  World Alzheimer Report 2015 - The Global Impact of Dementia: An analysis of prevalence, incidence, cost and trends , 2015 .

[21]  S. Sorbi,et al.  Csf p-tau181/tau ratio as biomarker for TDP pathology in frontotemporal dementia , 2015, Amyotrophic lateral sclerosis & frontotemporal degeneration.

[22]  S. Rossi,et al.  Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated report from an I.F.C.N. Committee , 2015, Clinical Neurophysiology.

[23]  Kenneth Rockwood,et al.  Diagnostic Criteria for Vascular Cognitive Disorders: A VASCOG Statement , 2014, Alzheimer disease and associated disorders.

[24]  S. Golaszewski,et al.  Transcranial magnetic stimulation (TMS)/repetitive TMS in mild cognitive impairment and Alzheimer's disease , 2014, Acta neurologica Scandinavica.

[25]  Marco Bozzali,et al.  Dopaminergic Modulation of Cortical Plasticity in Alzheimer’s Disease Patients , 2014, Neuropsychopharmacology.

[26]  E. D’Angelo,et al.  Cerebellar theta burst stimulation modulates short latency afferent inhibition in Alzheimer's disease patients , 2013, Front. Ag. Neurosci..

[27]  A. Wimo,et al.  The global prevalence of dementia: A systematic review and metaanalysis , 2013, Alzheimer's & Dementia.

[28]  C. Marra,et al.  Central cholinergic dysfunction measured “in vivo” correlates with different behavioral disorders in Alzheimer’s disease and dementia with Lewy body , 2012, Brain Stimulation.

[29]  Mousumi Banerjee,et al.  Identifying representative trees from ensembles , 2012, Statistics in medicine.

[30]  U. Ziemann,et al.  A practical guide to diagnostic transcranial magnetic stimulation: Report of an IFCN committee , 2012, Clinical Neurophysiology.

[31]  G. Bernardi,et al.  Cerebrospinal fluid levels of Aβ42 relationship with cholinergic cortical activity in Alzheimer’s disease patients , 2012, Journal of Neural Transmission.

[32]  David M. W. Powers,et al.  Evaluation: from precision, recall and F-measure to ROC, informedness, markedness and correlation , 2011, ArXiv.

[33]  Nick C Fox,et al.  Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. , 2011, Brain : a journal of neurology.

[34]  J. Hodges,et al.  Motor neuron dysfunction in frontotemporal dementia. , 2011, Brain : a journal of neurology.

[35]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[36]  B. Miller,et al.  Classification of primary progressive aphasia and its variants , 2011, Neurology.

[37]  C. Marra,et al.  In vivo functional evaluation of central cholinergic circuits in vascular dementia , 2008, Clinical Neurophysiology.

[38]  Anne-Laure Boulesteix,et al.  CMA – a comprehensive Bioconductor package for supervised classification with high dimensional data , 2008, BMC Bioinformatics.

[39]  M. Kronbichler,et al.  Abnormal short latency afferent inhibition in early Alzheimer’s disease: a transcranial magnetic demonstration , 2008, Journal of Neural Transmission.

[40]  Antonio Daniele,et al.  Functional evaluation of cerebral cortex in dementia with Lewy bodies , 2007, NeuroImage.

[41]  R. Nardone,et al.  Motor cortex inhibitory circuits in dementia with Lewy bodies and in Alzheimer’s disease , 2006, Journal of Neural Transmission.

[42]  A. Oliviero,et al.  In vivo cholinergic circuit evaluation in frontotemporal and Alzheimer dementias , 2006, Neurology.

[43]  S. Ghirlanda,et al.  Neurophysiological predictors of long term response to AChE inhibitors in AD patients , 2005, Journal of Neurology, Neurosurgery & Psychiatry.

[44]  D. Westaway,et al.  Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. , 2004, Journal of psychiatry & neuroscience : JPN.

[45]  G Gainotti,et al.  Motor cortex hyperexcitability to transcranial magnetic stimulation in Alzheimer’s disease , 2004, Journal of Neurology, Neurosurgery & Psychiatry.

[46]  K. Heilman,et al.  Relative Frequencies of Alzheimer Disease, Lewy Body, Vascular and Frontotemporal Dementia, and Hippocampal Sclerosis in the State of Florida Brain Bank , 2002, Alzheimer disease and associated disorders.

[47]  J. Rothwell,et al.  Noninvasive in vivo assessment of cholinergic cortical circuits in AD using transcranial magnetic stimulation , 2002, Neurology.

[48]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[49]  Russ B. Altman,et al.  Missing value estimation methods for DNA microarrays , 2001, Bioinform..

[50]  J. Rothwell,et al.  Short latency inhibition of human hand motor cortex by somatosensory input from the hand , 2000, The Journal of physiology.

[51]  Giovanni B. Frisoni,et al.  Consensus report of the working group on: 'Molecular and biochemical markers of Alzheimer's disease' , 1998 .

[52]  J. Rothwell,et al.  Interaction between intracortical inhibition and facilitation in human motor cortex. , 1996, The Journal of physiology.

[53]  C. Marsden,et al.  Corticocortical inhibition in human motor cortex. , 1993, The Journal of physiology.

[54]  M. Hallett,et al.  Human motor evoked responses to paired transcranial magnetic stimuli. , 1992, Electroencephalography and clinical neurophysiology.

[55]  C. Caltagirone,et al.  Reversal of LTP-Like Cortical Plasticity in Alzheimer's Disease Patients with Tau-Related Faster Clinical Progression. , 2016, Journal of Alzheimer's disease : JAD.

[56]  Andy Liaw,et al.  Classification and Regression by randomForest , 2007 .

[57]  Nancy Reagan,et al.  Consensus Report of the Working Group on: "Molecular and Biochemical Markers of Alzheimer's Disease" , 1998 .

[58]  G. Brier.  VERIFICATION OF FORECASTS EXPRESSED IN TERMS OF PROBABILITY , 1950 .