Confidence graphs for graphical model selection

In this article, we introduce the concept of confidence graphs (CG) for graphical model selection. CG first identifies two nested graphical models—called small and large confidence graphs (SCG and LCG)—trapping the true graphical model in between at a given level of confidence, just like the endpoints of traditional confidence interval capturing the population parameter. Therefore, SCG and LCG provide us with more insights about the simplest and most complex forms of dependence structure the true model can possibly be, and their difference also offers us a measure of model selection uncertainty. In addition, rather than relying on a single selected model, CG consists of a group of graphical models between SCG and LCG as the candidates. The proposed method can be coupled with many popular model selection methods, making it an ideal tool for comparing model selection uncertainty as well as measuring reproducibility. We also propose a new residual bootstrap procedure for graphical model settings to approximate the sampling distribution of the selected models and to obtain CG. To visualize the distribution of selected models and its associated uncertainty, we further develop new graphical tools, such as grouped model selection distribution plot. Numerical studies further illustrate the advantages of the proposed method.

[1]  Jing Lei,et al.  Cross-Validation With Confidence , 2017, Journal of the American Statistical Association.

[2]  K. Sachs,et al.  Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data , 2005, Science.

[3]  Hidetoshi Shimodaira An Application of Multiple Comparison Techniques to Model Selection , 1998 .

[4]  Tommi S. Jaakkola,et al.  Bias-Corrected Bootstrap and Model Uncertainty , 2003, NIPS.

[5]  Jianqing Fan,et al.  Sparsistency and Rates of Convergence in Large Covariance Matrix Estimation. , 2007, Annals of statistics.

[6]  Yuhong Yang,et al.  Confidence sets for model selection by F -testing , 2015 .

[7]  Y. Li,et al.  Model confidence bounds for variable selection , 2016, Biometrics.

[8]  Jianqing Fan,et al.  NETWORK EXPLORATION VIA THE ADAPTIVE LASSO AND SCAD PENALTIES. , 2009, The annals of applied statistics.

[9]  Yuhong Yang,et al.  Model Selection confidence sets by likelihood ratio testing , 2017, Statistica Sinica.

[10]  Jie Peng,et al.  BOOTSTRAP INFERENCE FOR NETWORK CONSTRUCTION WITH AN APPLICATION TO A BREAST CANCER MICROARRAY STUDY. , 2011, The annals of applied statistics.

[11]  D. Madigan,et al.  Model Selection and Accounting for Model Uncertainty in Graphical Models Using Occam's Window , 1994 .

[12]  Alexandre d'Aspremont,et al.  Model Selection Through Sparse Max Likelihood Estimation Model Selection Through Sparse Maximum Likelihood Estimation for Multivariate Gaussian or Binary Data , 2022 .

[13]  R. Tibshirani,et al.  Sparse inverse covariance estimation with the graphical lasso. , 2008, Biostatistics.

[14]  Han Liu,et al.  TIGER: A Tuning-Insensitive Approach for Optimally Estimating Gaussian Graphical Models , 2012, 1209.2437.

[15]  J. S. Rao,et al.  Fence methods for mixed model selection , 2008, 0808.0985.

[16]  Davide Ferrari,et al.  Ranking the importance of genetic factors by variable‐selection confidence sets , 2019, Journal of the Royal Statistical Society: Series C (Applied Statistics).

[17]  S. Lahiri,et al.  Bootstrapping Lasso Estimators , 2011 .

[18]  Yongli Zhang,et al.  LARGE MULTIPLE GRAPHICAL MODEL INFERENCE VIA BOOTSTRAP. , 2020, Statistica Sinica.

[19]  Trevor J. Hastie,et al.  The Graphical Lasso: New Insights and Alternatives , 2011, Electronic journal of statistics.

[20]  Eiko I. Fried,et al.  Estimating psychological networks and their accuracy: A tutorial paper , 2016, Behavior research methods.

[21]  N. Meinshausen,et al.  High-dimensional graphs and variable selection with the Lasso , 2006, math/0608017.

[22]  D. Freedman Bootstrapping Regression Models , 1981 .

[23]  Ali Jalali,et al.  High-dimensional Sparse Inverse Covariance Estimation using Greedy Methods , 2011, AISTATS.

[24]  M. Yuan,et al.  Model selection and estimation in the Gaussian graphical model , 2007 .

[25]  Susan A. Murphy,et al.  Monographs on statistics and applied probability , 1990 .

[26]  Peter Reinhard Hansen,et al.  The Model Confidence Set , 2010 .

[27]  Xiaotong Shen,et al.  Journal of the American Statistical Association Likelihood-based Selection and Sharp Parameter Estimation Likelihood-based Selection and Sharp Parameter Estimation , 2022 .