New strategies for using mucosal vaccination to achieve more effective immunization.

[1]  E. Claassen,et al.  New and safe "oral" live vaccines based on lactobacillus. , 1995, Advances in experimental medicine and biology.

[2]  E. Brunschwig,et al.  Oral immunization against respiratory viruses in mice. , 1995, Advances in experimental medicine and biology.

[3]  J. Mekalanos Live Attenuated Vaccine Vectors , 1994, International Journal of Technology Assessment in Health Care.

[4]  J. Mcghee,et al.  Effective Mucosal Immunity: Current Concepts for Vaccine Delivery and Immune Response Analysis , 1994, International Journal of Technology Assessment in Health Care.

[5]  J. Kraehenbuhl,et al.  Induction of specific immunoglobulin A in the small intestine, colon-rectum, and vagina measured by a new method for collection of secretions from local mucosal surfaces , 1994, Infection and immunity.

[6]  M. Estes,et al.  Rotavirus vaccine administered parenterally induces protective immunity , 1993, Journal of virology.

[7]  J. Clements,et al.  Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant. , 1993, Vaccine.

[8]  R. G. Douglas The Children's Vaccine Initiative--will it work? , 1993, The Journal of infectious diseases.

[9]  C. Elson,et al.  Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptide addition , 1993, Infection and immunity.

[10]  K. Timmis,et al.  Antibody responses in the serum and respiratory tract of mice following oral vaccination with liposomes coated with filamentous hemagglutinin and pertussis toxoid , 1993, Infection and immunity.

[11]  C. Elson,et al.  Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines , 1993, Infection and immunity.

[12]  M. Russell,et al.  Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit , 1993, Infection and immunity.

[13]  L. Irons,et al.  Adjuvant action of cholera toxin and pertussis toxin in the induction of IgA antibody response to orally administered antigen. , 1993, Vaccine.

[14]  R. Compans,et al.  Oral immunization with influenza virus in biodegradable microspheres. , 1993, The Journal of infectious diseases.

[15]  J. Morris,et al.  Human immune response to Campylobacter jejuni proteins expressed in vivo , 1992, Infection and immunity.

[16]  A. C. Ghose,et al.  Major outer membrane proteins of Vibrio cholerae and their role in induction of protective immunity through inhibition of intestinal colonization , 1992, Infection and immunity.

[17]  J. Holmgren,et al.  Protection against Vibrio cholerae El Tor infection by specific antibodies against mannose-binding hemagglutinin pili , 1992, Infection and immunity.

[18]  R. Weiss Measles battle loses potent weapon. , 1992, Science.

[19]  R. Betts,et al.  Protective Efficacy of Combined Live Intranasal and Inactivated Influenza A Virus Vaccines in the Elderly , 1992, Annals of Internal Medicine.

[20]  M. Levine,et al.  Onset and duration of protective immunity in challenged volunteers after vaccination with live oral cholera vaccine CVD 103-HgR. , 1992, The Journal of infectious diseases.

[21]  K. Timmis,et al.  Specific lung mucosal and systemic immune responses after oral immunization of mice with Salmonella typhimurium aroA, Salmonella typhi Ty21a, and invasive Escherichia coli expressing recombinant pertussis toxin S1 subunit , 1992, Infection and immunity.

[22]  Suharyono,et al.  Safety and immunogenicity of single-dose live oral cholera vaccine CVD 103-HgR in 5-9-year-old Indonesian children , 1992, The Lancet.

[23]  J. Holmgren,et al.  The adjuvant effect of Vibrio cholerae and Escherichia coli heat‐labile enterotoxins is linked to their ADP‐ribosyltransferase activity , 1992, European journal of immunology.

[24]  H. Maassab,et al.  Evaluation of a cold-adapted influenza B/Texas/84 reassortant virus (CRB-87) vaccine in young children , 1992, Journal of clinical microbiology.

[25]  R. Schneerson,et al.  Hypothesis for vaccine development: protective immunity to enteric diseases caused by nontyphoidal salmonellae and shigellae may be conferred by serum IgG antibodies to the O-specific polysaccharide of their lipopolysaccharides. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[26]  J. McKeating,et al.  Vaginal immunization of rats with a synthetic peptide from human immunodeficiency virus envelope glycoprotein. , 1992, The Journal of general virology.

[27]  R. Gupta,et al.  Synthesis, characterization, and some immunological properties of conjugates composed of the detoxified lipopolysaccharide of Vibrio cholerae O1 serotype Inaba bound to cholera toxin , 1992, Infection and immunity.

[28]  B. Subbarao,et al.  Immune responses of systemic and mucosal lymphoid organs to Pnu-Imune vaccine as a function of age and the efficacy of monophosphoryl lipid A as an adjuvant , 1992, Infection and immunity.

[29]  M. Levine,et al.  Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen , 1992, Infection and immunity.

[30]  J. Mekalanos,et al.  Monoclonal secretory immunoglobulin A protects mice against oral challenge with the invasive pathogen Salmonella typhimurium , 1992, Infection and immunity.

[31]  N. Lycke,et al.  Cholera toxin adjuvant promotes long-term immunological memory in the gut mucosa to unrelated immunogens after oral immunization. , 1992, Immunology.

[32]  B. Forrest,et al.  Effect of parenteral immunization on the intestinal immune response to Salmonella typhi Ty21a , 1992, Infection and immunity.

[33]  R. Walker,et al.  Experimental oral Campylobacter vaccine , 1992 .

[34]  R. Walker,et al.  Prospects and problems for development of a vaccine against diarrhea caused by Campylobacter , 1992 .

[35]  E. Boedeker,et al.  Microencapsulated pili promote cellular immune responses following enteric administration , 1992 .

[36]  D. Cohen,et al.  Oral or intranasal immunization with shigella LPS complexed to proteosomes induces intestinal and serum IgA and IgG , 1992 .

[37]  F. Graham,et al.  Adenovirus-based expression vectors and recombinant vaccines. , 1992, Biotechnology.

[38]  J. Biewenga,et al.  The role of nasopharyngeal lymphoid tissue. , 1992, Immunology today.

[39]  A. Lindberg,et al.  Safety and immunogenicity of the live oral auxotrophic Shigella flexneri SFL124 in volunteers. , 1992, Vaccine.

[40]  T. Kurata,et al.  Stimulation of the transepithelial flux of influenza HA vaccine by cholera toxin B subunit. , 1992, Vaccine.

[41]  R. Whitley,et al.  Herpes simplex vaccines. , 1992, Biotechnology.

[42]  I. Maclennan,et al.  Germinal centres in T-cell-dependent antibody responses. , 1992, Immunology today.

[43]  E. Abraham Intranasal immunization with bacterial polysaccharide containing liposomes enhances antigen-specific pulmonary secretory antibody response. , 1992, Vaccine.

[44]  J. Mcghee,et al.  The mucosal immune system: from fundamental concepts to vaccine development. , 1992, Vaccine.

[45]  H. Faden Results of a clinical study of polio vaccine: the Buffalo experience , 1991, The Pediatric infectious disease journal.

[46]  S. Plotkin Current issues in evaluating the efficacy of oral poliovirus vaccine and inactivated poliovirus vaccine immunization , 1991, The Pediatric infectious disease journal.

[47]  J. Modlin Mucosal immunity following oral poliovirus vaccine and enhanced potency inactivated poliovirus vaccine immunization , 1991, The Pediatric infectious disease journal.

[48]  A. Donachie,et al.  ISCOMS--a novel strategy for mucosal immunization? , 1991, Immunology today.

[49]  T. Kurata,et al.  The effect of cholera toxin and cholera toxin B subunit on the nasal mucosal membrane. , 1991, Vaccine.

[50]  E. Abraham,et al.  Oral immunization with bacterial polysaccharide and adjuvant enhances antigen-specific pulmonary secretory antibody response and resistance to pneumonia. , 1991, Vaccine.

[51]  G. Mogi,et al.  Oral vaccine therapy for pneumococcal otitis media in an animal model. , 1991, Archives of otolaryngology--head & neck surgery.

[52]  S. Czinn,et al.  Oral immunization against Helicobacter pylori , 1991, Infection and immunity.

[53]  A. Sjölander,et al.  The Adjuvant Action of Cholera Toxin is Associated with an Increased Intestinal Permeability for Luminal Antigens , 1991, Scandinavian journal of immunology.

[54]  J. Holmgren,et al.  Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro. , 1991, Journal of immunology.

[55]  P. Ogra,et al.  Induction of antibody response to Chlamydia trachomatis in the genital tract by oral immunization , 1991, Infection and immunity.

[56]  O. Jarrett,et al.  Immune-stimulating complexes containing Quil A and protein antigen prime class I MHC-restricted T lymphocytes in vivo and are immunogenic by the oral route. , 1991, Immunology.

[57]  I. Haffejee The status of rotavirus vaccines in 1990. , 1991, The Journal of infection.

[58]  J. Mcghee,et al.  Biodegradable microspheres as a vaccine delivery system. , 1991, Molecular immunology.

[59]  R Weltzin,et al.  New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection , 1991, Infection and immunity.

[60]  Takumi,et al.  Effectiveness of enteric immunization in the development of secretory immunoglobulin A response and the outcome of infection with respiratory syncytial virus , 1991, Journal of virology.

[61]  R. Chanock,et al.  Recent advances in development of a rotavirus vaccine for prevention of severe diarrheal illness of infants and young children. , 1991, Advances in experimental medicine and biology.

[62]  K. Lövgren,et al.  An experimental influenza subunit vaccine (iscom): induction of protective immunity to challenge infection in mice after intranasal or subcutaneous administration , 1990, Clinical and experimental immunology.

[63]  A. McBean,et al.  Comparative evaluation of immunization with live attenuated and enhanced-potency inactivated trivalent poliovirus vaccines in childhood: systemic and local immune responses. , 1990, The Journal of infectious diseases.

[64]  C. Manclark,et al.  Mechanism of pertussis toxin B oligomer-mediated protection against Bordetella pertussis respiratory infection , 1990, Infection and immunity.

[65]  N. Lycke,et al.  Cholera toxin acts synergistically with IL-4 to promote IgG1 switch differentiation. , 1990, Journal of immunology.

[66]  J. Sadoff,et al.  Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells , 1990, The Journal of experimental medicine.

[67]  G. Cornelis,et al.  Oral immunization of mice with a live recombinant Yersinia enterocolitica O:9 strain that produces the cholera toxin B subunit , 1990, Infection and immunity.

[68]  M. McDermott,et al.  Mucosal and systemic antiviral antibodies in mice inoculated intravaginally with herpes simplex virus type 2. , 1990, The Journal of general virology.

[69]  B. Huber,et al.  Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation , 1990, The Journal of experimental medicine.

[70]  D. OʼHagan Novel nonreplicating antigen delivery systems , 1990 .

[71]  K. Redhead,et al.  Vaccines against pertussis , 1990 .

[72]  T. Nagamine,et al.  Comparison of intranasal inoculation of influenza HA vaccine combined with cholera toxin B subunit with oral or parenteral vaccination. , 1990, Vaccine.

[73]  B. Forrest,et al.  Specific immune response in humans following rectal delivery of live typhoid vaccine. , 1990, Vaccine.

[74]  S. Michalek,et al.  Liposomes containing anti-idiotypic antibodies: an oral vaccine to induce protective secretory immune responses specific for pathogens of mucosal surfaces , 1990, Infection and immunity.

[75]  C. Stokes,et al.  Whole Cholera Toxin and B Subunit Act Synergistically as an Adjuvant for the Mucosal Immune Response of Mice to Keyhole Limpet Haemocyanin , 1990, Scandinavian journal of immunology.

[76]  Yunus,et al.  Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up , 1990, The Lancet.

[77]  Thomas R. Tice,et al.  Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches , 1990 .

[78]  R. Glass,et al.  Development of vaccines against cholera and diarrhoea due to enterotoxigenic Escherichia coli: Memorandum from a WHO meeting , 1990 .

[79]  J. Holmgren,et al.  Development of oral vaccines against cholera and enterotoxinogenic Escherichia coli diarrhea. , 1990, Scandinavian journal of infectious diseases. Supplementum.

[80]  J. Hackett,et al.  Vaccination against enteric bacterial diseases. , 1989, Reviews of infectious diseases.

[81]  T. Ogawa,et al.  Mucosal and systemic immune responses in BALB/c mice to Bacteroides gingivalis fimbriae administered orally , 1989, Infection and immunity.

[82]  M. Lamm,et al.  Cholera toxin as a mucosal adjuvant. Glutaraldehyde treatment dissociates adjuvanticity from toxicity. , 1989, Journal of immunology.

[83]  Henry Nider,et al.  Report of the Committee on Infectious Diseases , 1989 .

[84]  C. Czerkinsky,et al.  Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues , 1989, Infection and immunity.

[85]  R. Mannino,et al.  Intranasal immunization with proteoliposomes protects against influenza. , 1989, Vaccine.

[86]  D. Keren,et al.  Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis , 1989, Infection and immunity.

[87]  D. Cohen,et al.  Immunoglobulin M, A, and G antibody response to lipopolysaccharide O antigen in symptomatic and asymptomatic Shigella infections , 1989, Journal of clinical microbiology.

[88]  J. Mcghee,et al.  Oral immunization: past and present. , 1989, Current topics in microbiology and immunology.

[89]  P. Brandtzaeg Overview of the mucosal immune system. , 1989, Current topics in microbiology and immunology.

[90]  C. Elson Cholera toxin and its subunits as potential oral adjuvants. , 1989, Current topics in microbiology and immunology.

[91]  L. Hanson,et al.  Induction of the mucosal immune response. , 1989, Current topics in microbiology and immunology.

[92]  K. Bergmann,et al.  Oral immunization with influenza virus: experimental and clinical studies. , 1989, Current topics in microbiology and immunology.

[93]  G. Quinnan,,et al.  Induction, persistence and strain specificity of haemagglutinin-specific secretory antibodies in lungs of mice after intragastric administration of inactivated influenza virus vaccines. , 1988, The Journal of general virology.

[94]  T. Nagamine,et al.  Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit. , 1988, Vaccine.

[95]  K. Bergmann,et al.  Stimulation of secretory antibody following oral administration of antigen. , 1988, Reviews of infectious diseases.

[96]  C. Tacket,et al.  SAFETY, IMMUNOGENICITY, AND EFFICACY OF RECOMBINANT LIVE ORAL CHOLERA VACCINES, CVD 103 AND CVD 103-HgR , 1988, The Lancet.

[97]  F. L. Lyon,et al.  Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens. , 1988, Vaccine.

[98]  J. Mekalanos,et al.  Safe, live Vibrio cholerae vaccines? , 1988, Vaccine.

[99]  R. McDonald,et al.  Combined parenteral and oral immunization results in an enhanced mucosal immunoglobulin A response to Shigella flexneri , 1988, Infection and immunity.

[100]  K. Lövgren The Serum Antibody Response Distributed in Subclasses and Isotypes after Intranasal and Subcutaneous Immunization with Influenza Virus Immunostimulating Complexes , 1988, Scandinavian journal of immunology.

[101]  G. Russell-Jones,et al.  Oral vaccination. Identification of classes of proteins that provoke an immune response upon oral feeding , 1988, The Journal of experimental medicine.

[102]  W. Cray,et al.  Bacterial characteristics and follicle surface structure: their roles in Peyer's patch uptake and transport of Vibrio cholerae. , 1988, Advances in experimental medicine and biology.

[103]  M. Lamm,et al.  Combined oral/nasal immunization protects mice from Sendai virus infection. , 1987, Journal of immunology.

[104]  N. Weiner,et al.  Gastrointestinal uptake of liposomes. I. In vitro and in situ studies , 1987 .

[105]  U. Dahlgren,et al.  The localization of the antibody response in milk or bile depends on the nature of the antigen. , 1987, Journal of immunology.

[106]  J. L. Montagne,et al.  Influenza vaccine and pneumonia mortality in a nursing home population. , 1986, Archives of internal medicine.

[107]  R. Rowland,et al.  The number and distribution of lymphoid follicles in the human large intestine. , 1986, Journal of anatomy.

[108]  J. Holmgren,et al.  Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. , 1986, Immunology.

[109]  D. Sack,et al.  FIELD TRIAL OF ORAL CHOLERA VACCINES IN BANGLADESH , 1986, The Lancet.

[110]  W. Cray,et al.  M cell transport of Vibrio cholerae from the intestinal lumen into Peyer's patches: a mechanism for antigen sampling and for microbial transepithelial migration. , 1986, The Journal of infectious diseases.

[111]  A. Sabin,et al.  High effectiveness of aerosolized chick embryo fibroblast measles vaccine in seven-month-old and older infants. , 1985, The Journal of infectious diseases.

[112]  N. Delimar,et al.  INTRANASAL ADMINISTRATION OF CHICK EMBRYO FIBROBLAST EDMONSTON-ZAGREB MEASLES VACCINE , 1985, The Lancet.

[113]  J. Arroyo,et al.  Influenza A/Philippines/2/82 outbreak in a nursing home: limitations of influenza vaccination in the aged. , 1984, American journal of infection control.

[114]  H. Whittle,et al.  IMMUNISATION OF 4-6 MONTH OLD GAMBIAN INFANTS WITH EDMONSTON-ZAGREB MEASLES VACCINE , 1984, The Lancet.

[115]  J. Halsey,et al.  Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune response. , 1984, Journal of immunology.

[116]  C. Elson,et al.  Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin. , 1984, Journal of immunology.

[117]  J. Bienenstock,et al.  Regulation of lymphoblast traffic and localization in mucosal tissues, with emphasis on IgA. , 1983, Federation proceedings.

[118]  J. Bienenstock,et al.  THE MUCOSAL IMMUNOLOGICAL NETWORK: COMPARTMENTALIZATION OF LYMPHOCYTES, NATURAL KILLER CELLS, AND MAST CELLS * , 1983, Annals of the New York Academy of Sciences.

[119]  J. Ebersole,et al.  ADJUVANTS FOR SECRETORY IMMUNE RESPONSES * , 1983, Annals of the New York Academy of Sciences.

[120]  M. Torii,et al.  Effective immunity to dental caries: enhancement of salivary anti-Streptococcus mutans antibody responses with oral adjuvants , 1983, Infection and immunity.

[121]  M. Szewczuk,et al.  Lack of age-associated immune dysfunction in mucosal-associated lymph nodes. , 1981, Journal of immunology.

[122]  J. Holmgren,et al.  Different secretory immunoglobulin A antibody responses to cholera vaccination in Swedish and Pakistani women , 1980, Infection and immunity.

[123]  Reynolds Ja,et al.  Adjuvant effects of the lipid amine CP-20,961. , 1979 .

[124]  D. Rowley,et al.  Persistence in the mouse gut as an important factor in oral immunogenicity of strains of V. cholerae. , 1979, The Australian journal of experimental biology and medical science.

[125]  D. Rowley,et al.  Local immune response in mice to Vibrio cholerae. , 1979, The Australian journal of experimental biology and medical science.

[126]  J M Brady,et al.  Degradation rates of oral resorbable implants (polylactates and polyglycolates): rate modification with changes in PLA/PGA copolymer ratios. , 1977, Journal of biomedical materials research.

[127]  J. Kaur,et al.  Immunity to cholera: antibody response in the lower ileum of the rabbit. , 1971, The Journal of infectious diseases.

[128]  P. Wernet,et al.  Antibacterial action of specific IgA and transport of IgM, IgA, and IgG from serum into the small intestine. , 1971, The Journal of infectious diseases.

[129]  L. H. Greenberg,et al.  Factor XIII deficiency. Treatment with monthly plasma infusions. , 1969, JAMA.

[130]  P. Ogra,et al.  Distribution of poliovirus antibody in serum, nasopharynx and alimentary tract following segmental immunization of lower alimentary tract with poliovaccine. , 1969, Journal of immunology.

[131]  S. Formal,et al.  Failure of Parenteral Vaccines to Protect Monkeys Against Experimental Shigellosis , 1967, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.