Challenges to curing primary brain tumours
暂无分享,去创建一个
Giles W. Robinson | Paul Workman | Amar Gajjar | David T. W. Jones | John H. Sampson | Mark R. Gilbert | Darren Hargrave | Kevin M. Brindle | Rajesh Chopra | Eric C. Holland | Mark W. Kieran | Louis Chesler | David H. Gutmann | Ingo K. Mellinghoff | Jeremy N. Rich | Vijay Ramaswamy | Richard J. Gilbertson | K. Aldape | M. Gilbert | I. Mellinghoff | D. Rowitch | P. Kearns | E. Holland | R. Gilbertson | D. Gutmann | K. Brindle | P. Workman | J. Rich | Michael D. Taylor | D. Hargrave | R. Chopra | M. Kieran | S. Pollard | A. Gajjar | N. Gottardo | V. Ramaswamy | J. Sampson | J. Joyce | G. Robinson | L. Chesler | David H. Rowitch | M. Merchant | Kenneth Aldape | Pamela Kearns | Johanna A. Joyce | Steven M. Pollard | Nicholas Gottardo | Melinda Merchant | Stefan M. Pfister | S. M. Pfister | S. Pfister
[1] J. Gartner,et al. Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer , 2018, Nature Medicine.
[2] M. Oldham,et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. , 2018, Cancer cell.
[3] A. Abbott. Is ‘friendly fire’ in the brain provoking Alzheimer’s disease? , 2018, Nature.
[4] Till Acker,et al. DNA methylation-based classification of central nervous system tumours , 2018, Nature.
[5] F. Zipp,et al. EGFL7 reduces CNS inflammation in mouse , 2018, Nature Communications.
[6] Koji Ando,et al. A molecular atlas of cell types and zonation in the brain vasculature , 2018, Nature.
[7] Wei-Hao Liao,et al. Focused shockwave induced blood-brain barrier opening and transfection , 2018, Scientific Reports.
[8] M. Roussel,et al. Establishing a Preclinical Multidisciplinary Board for Brain Tumors , 2018, Clinical Cancer Research.
[9] N. Perrimon,et al. Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA) , 2017, Proceedings of the National Academy of Sciences.
[10] K. Cole,et al. Comprehensive Analysis of Hypermutation in Human Cancer , 2017, Cell.
[11] Steven D Chang,et al. Single-Cell RNAseq analysis of infiltrating neoplastic cells at the migrating front of human glioblastoma , 2017, bioRxiv.
[12] Kun Mu,et al. Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma , 2017, Cancer cell.
[13] Brian M Alexander,et al. Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE , 2017, Clinical Cancer Research.
[14] K. Brindle,et al. Brain Tumor Imaging. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[15] C. June,et al. Immunotherapy for Brain Tumors. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] M. Weller,et al. Vaccine-based immunotherapeutic approaches to gliomas and beyond , 2017, Nature Reviews Neurology.
[17] James D. Brenton,et al. Liquid biopsies come of age: towards implementation of circulating tumour DNA , 2017, Nature Reviews Cancer.
[18] D. Quail,et al. The Microenvironmental Landscape of Brain Tumors. , 2017, Cancer cell.
[19] F. Wong,et al. Brain Tumor Imaging , 2017, The Journal of Nuclear Medicine.
[20] E. De Carli,et al. [Immunotherapy in brain tumors]. , 2017, Annales de pathologie.
[21] K. Aldape,et al. The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants , 2016, Acta Neuropathologica.
[22] Mariella G. Filbin,et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma , 2016, Nature.
[23] G. Armstrong,et al. Hypothalamic-Pituitary Axis Dysfunction in Survivors of Childhood CNS Tumors: Importance of Systematic Follow-Up and Early Endocrine Consultation. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] K. Walsh,et al. Intellectual Outcome in Molecular Subgroups of Medulloblastoma. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[25] J. Prehn,et al. Advances in immunotherapy for the treatment of glioblastoma , 2016, Journal of Neuro-Oncology.
[26] B. Geoerger,et al. CNS tumoursThe first study of dabrafenib in pediatric patients with BRAF V600–mutant relapsed or refractory low-grade gliomas , 2016 .
[27] T. Merchant,et al. Long-Term Neurocognitive Functioning and Social Attainment in Adult Survivors of Pediatric CNS Tumors: Results From the St Jude Lifetime Cohort Study. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] Ian Law,et al. Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas. , 2016, Neuro-oncology.
[29] S. Cichon,et al. Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma , 2016, Clinical Cancer Research.
[30] In-Hee Lee,et al. Clonal evolution of glioblastoma under therapy , 2016, Nature Genetics.
[31] K. Hoang-Xuan,et al. Clinical trial of blood-brain barrier disruption by pulsed ultrasound , 2016, Science Translational Medicine.
[32] A. Viale,et al. Evaluating Cancer of the Central Nervous System Through Next-Generation Sequencing of Cerebrospinal Fluid , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] G. Reifenberger,et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary , 2016, Acta Neuropathologica.
[34] R. Stupp,et al. Corticosteroids compromise survival in glioblastoma. , 2016, Brain : a journal of neurology.
[35] A. Álvarez-Buylla,et al. The Adult Ventricular-Subventricular Zone (V-SVZ) and Olfactory Bulb (OB) Neurogenesis. , 2016, Cold Spring Harbor perspectives in biology.
[36] Qiulian Wu,et al. A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo. , 2016, Cancer research.
[37] Mark L. Greenberg,et al. Clinical and treatment factors determining long‐term outcomes for adult survivors of childhood low‐grade glioma: A population‐based study , 2016, Cancer.
[38] M. Roussel,et al. Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype. , 2016, Cancer cell.
[39] W. Banks,et al. From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery , 2016, Nature Reviews Drug Discovery.
[40] S. Razavi,et al. Immune Evasion Strategies of Glioblastoma , 2016, Front. Surg..
[41] Roland Eils,et al. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs , 2016, Cell.
[42] Gary D. Bader,et al. Divergent clonal selection dominates medulloblastoma at recurrence , 2016, Nature.
[43] C. Stewart,et al. Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature , 2016, Clinical Pharmacokinetics.
[44] Emily J. Girard,et al. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. , 2015, Cell reports.
[45] Jonathan Kipnis,et al. Revisiting the Mechanisms of CNS Immune Privilege. , 2015, Trends in immunology.
[46] J. Rich,et al. Cancer stem cells in glioblastoma , 2015, Genes & development.
[47] Traci M. Blonquist,et al. Polymorphisms in Genes Related to Oxidative Stress Are Associated With Inferior Cognitive Function After Therapy for Childhood Acute Lymphoblastic Leukemia. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[48] D. Ellison,et al. An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes , 2015, Nature Genetics.
[49] Gelareh Zadeh,et al. Glioblastoma: pathology, molecular mechanisms and markers , 2015, Acta Neuropathologica.
[50] Gary D Bader,et al. Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. , 2015, Cancer cell.
[51] M. Chintagumpala,et al. Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss , 2015, Nature Genetics.
[52] Christopher S. Bjornsson,et al. It takes a village: constructing the neurogenic niche. , 2015, Developmental cell.
[53] Malcolm A. Smith,et al. Remaining challenges in childhood cancer and newer targeted therapeutics. , 2015, Pediatric clinics of North America.
[54] Helmut Kettenmann,et al. The role of microglia and macrophages in glioma maintenance and progression , 2015, Nature Neuroscience.
[55] S. Fields,et al. Deep mutational scanning: a new style of protein science , 2014, Nature Methods.
[56] Gary D Bader,et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma , 2014, Nature.
[57] J. Joyce,et al. Therapeutic targeting of tumor-associated macrophages and microglia in glioblastoma. , 2014, Immunotherapy.
[58] Li Ding,et al. C11ORF95-RELA FUSIONS DRIVE ONCOGENIC NF-KB SIGNALING IN EPENDYMOMA. , 2014 .
[59] Shawn M. Gillespie,et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma , 2014, Science.
[60] K. Hoang-Xuan,et al. Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma. , 2014, The New England journal of medicine.
[61] Li Ding,et al. C11orf95-RELA fusions drive oncogenic NF-κB signaling in ependymoma , 2014, Nature.
[62] K. Aldape,et al. A randomized trial of bevacizumab for newly diagnosed glioblastoma. , 2014, The New England journal of medicine.
[63] Shein-Chung Chow,et al. Adaptive clinical trial design. , 2014, Annual review of medicine.
[64] D. Quail,et al. Microenvironmental regulation of tumor progression and metastasis , 2014 .
[65] Carmen L. Wilson,et al. Chemotherapy-related neuropathic symptoms and functional impairment in adult survivors of extracranial solid tumors of childhood: results from the St. Jude Lifetime Cohort Study. , 2013, Archives of physical medicine and rehabilitation.
[66] Scott L. Pomeroy,et al. Medulloblastomics: the end of the beginning , 2012, Nature Reviews Cancer.
[67] D. Brat,et al. Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma , 2012, Science.
[68] Gilbert Vezina,et al. Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[69] Tzong-Shiue Yu,et al. A restricted cell population propagates glioblastoma growth following chemotherapy , 2012, Nature.
[70] M. Giovannini,et al. WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum , 2012, Development.
[71] David T. W. Jones,et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma , 2012, Nature.
[72] S. Scherer,et al. Clonal Selection Drives Genetic Divergence of Metastatic Medulloblastoma , 2012, Nature.
[73] J. Stockman,et al. Everolimus for Subependymal Giant-Cell Astrocytomas in Tuberous Sclerosis , 2012 .
[74] Tzong-Shiue Yu,et al. A restricted cell population propagates glioblastoma growth after chemotherapy , 2012 .
[75] W. Yung,et al. An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma. , 2011, Cancer cell.
[76] R. Gilbertson,et al. Mapping Cancer Origins , 2011, Cell.
[77] James B. Mitchell,et al. Detecting response of rat C6 glioma tumors to radiotherapy using hyperpolarized [1‐13C]pyruvate and 13C magnetic resonance spectroscopic imaging , 2011, Magnetic resonance in medicine.
[78] B. Barres,et al. Pericytes are required for blood–brain barrier integrity during embryogenesis , 2010, Nature.
[79] F. Ginhoux,et al. Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.
[80] A. Byars,et al. Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. , 2010, The New England journal of medicine.
[81] Yiai Tong,et al. Subtypes of medulloblastoma have distinct developmental origins , 2010, Nature.
[82] Amar Gajjar,et al. Cross-species genomics matches driver mutations and cell compartments to model ependymoma , 2010, Nature.
[83] Susan M. Chang,et al. Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[84] Arnold Kriegstein,et al. The glial nature of embryonic and adult neural stem cells. , 2009, Annual review of neuroscience.
[85] F. Turkheimer,et al. A new model for prediction of drug distribution in tumor and normal tissues: pharmacokinetics of temozolomide in glioma patients. , 2009, Cancer research.
[86] B. Scheithauer,et al. The 2007 WHO classification of tumours of the central nervous system , 2007, Acta Neuropathologica.
[87] E. Gerstner,et al. Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigm. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[88] I. Bayazitov,et al. A perivascular niche for brain tumor stem cells. , 2007, Cancer cell.
[89] E. Hansson,et al. Astrocyte–endothelial interactions at the blood–brain barrier , 2006, Nature Reviews Neuroscience.
[90] Douglas C. Miller,et al. Multiagent chemotherapy and deferred radiotherapy in infants with malignant brain tumors: a report from the Children's Cancer Group. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[91] Amar Gajjar,et al. Radial glia cells are candidate stem cells of ependymoma. , 2005, Cancer cell.
[92] T. Davis,et al. The Blood-Brain Barrier/Neurovascular Unit in Health and Disease , 2005, Pharmacological Reviews.
[93] L. D.,et al. Brain tumors , 2005, Psychiatric Quarterly.
[94] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[95] B. Scheithauer,et al. Microglia in brain tumors , 2002, Glia.
[96] D. Steindler,et al. Human cortical glial tumors contain neural stem‐like cells expressing astroglial and neuronal markers in vitro , 2002, Glia.
[97] R. Sposto,et al. Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group. , 2001, Medical and pediatric oncology.
[98] L. Rorke,et al. Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group Study. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[99] M. Scott,et al. Altered neural cell fates and medulloblastoma in mouse patched mutants. , 1997, Science.
[100] G. Reaman,et al. Correlation of P-glycoprotein expression and function in childhood acute leukemia: a children's cancer group study. , 1996, Blood.
[101] S. Leeder,et al. A population based study , 1993, The Medical journal of Australia.
[102] M E Cohen,et al. Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. , 1993, The New England journal of medicine.
[103] S. Segawa,et al. End of the beginning , 1990, Nature.
[104] J. Sneep,et al. With a summary , 1945 .