Part I:Introduction Water-Lipid Interaction, Bozena B. Michniak, Philip W. Wertz Water-Keratin Interaction, Jean-Luc Leveque Stratum Corneum pH: and Ions - Distribution and Importance, Joachim W Fluhr, Lora Bankova, Peter Elias Occlusion, Jana Prassler, Joachim W Fluhr Part II: Transepidermal Water Loss and Barrier Function Transepidermal Water Loss Measurements in Dermato-Cosmetic Sciences, Vera Rogiers, E. Houben, K. De Paepe Ultrasound and Water in the Stratum Corneum, Stefania Seidenari, Giovanni Pellacani Standardization of Measurements and Guidelines, Grazia Primavera, Joachim W. Fluhr, Enzo Berardesca Transepidermal Water Loss (TEWL) and its Relation to Barrier Function and Skin Irritation, P.G.M. Van der Valk, M Kucharekova, R.A. Tupker Transepidermal Water Loss and Allergic Contact Dermatitis, Stefania Seidenari, Francesca Giusti Prediction of Irritancy, R.A. Tupker TEWL and Racial differences, Grazia Primavera, Enzo Berardesca Sensitive Skin and Transepidermal Water Loss (TEWL), Clarissa D. Villarama, Howard I. Maibach Transepidermal Water Loss and Barrier Function of Aging Human Skin, Klaus-P. Wilhelm, Marianne Brandt, Howard I. Maibach Atopic Dermatitis and Other Skin Diseases, Manige Fartasch Transepidermal Water Loss and Dry Skin, Marie Loden Bioengineering Correlates of the Sensitive Skin Syndrome: The Sensory Irritation Component, Robert Sinaiko, Howard I. Maibach Barrier Recovery, Silke M. Fuchs, Joachim W. Fluhr, Howard I. Maibach Testing the Efficacy of Moisturizer, Bemard Gabard Dynamic Measurements: POST, MAT and SDT, Grazia Primavera, Enzo Berardesca Part III: Water Content Assessment of Stratum Corneum Hydration: Corneometer CM 825, Gabriel Khazaka Hardware and Measuring Principles: The NOVATM DPM, Randy Wickett Hardware and Measuring Principles: The Computerized DermaLab(R) TEWL Probe, Gary L. Grove, Charles Zerweck Electrical Assessment of Skin Hydration: Standardization of Measurements and Guidelines, Grazia Primavera, Joachim W. Fluhr, Enzo Berardesca Hydration and Moisturizers, Marie Loden Infant Skin Hydration, Marty O. Visscher, Steven B. Hoath Hydration and Atopic Dermatitis, Chris Edwards Within and Beyond the Skin Barrier as Seen by Electrical Impedance , Stig Ollmar, Ingrid Nicander Hydration, Psoriasis and Ekzema: The Dry Surface-High Evaporative Water Loss Paradox, Jorgen Serup Hydration and Lipids , Philip W. Wertz, Bozena B. Michniak Xerotic Skin and Impairment of Barrier Function Associated to Itch, Gil Yosipovitch Testing and Efficacy of Barrier Creams, Hongbo Zhai, Howard I. Maibach Testing of Moisturizer, Marie Loden, Magnus Lindberg