(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the β1-adrenoceptor
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K. Fong | I. Yang | P. Molenaar | J. Lynham | A. Kaumann | F. Russell | G. Rabnott | D. Sarsero | Li Li
[1] K. Fong,et al. Conservation of the cardiostimulant effects of (-)-norepinephrine across Ser49Gly and Gly389Arg beta(1)-adrenergic receptor polymorphisms in human right atrium in vitro. , 2002, Journal of the American College of Cardiology.
[2] R. Olshen,et al. A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. , 2002, American journal of human genetics.
[3] A. Grace,et al. Comparison of the affinity of β‐blockers for two states of the β1‐adrenoceptor in ferret ventricular myocardium , 2002 .
[4] L. Groop,et al. Polymorphism in the &bgr;1-Adrenergic Receptor Gene and Hypertension , 2001, Circulation.
[5] J. Port,et al. Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure. , 2001, Journal of molecular and cellular cardiology.
[6] R. Kim,et al. Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo. , 2001, Pharmacogenetics.
[7] P. Insel,et al. In-vivo studies do not support a major functional role for the Gly389Arg beta 1-adrenoceptor polymorphism in humans. , 2001, Pharmacogenetics.
[8] J. Granneman,et al. The putative β4-adrenergic receptor is a novel state of the β1-adrenergic receptor , 2001 .
[9] M. Börjesson,et al. A novel polymorphism in the gene coding for the beta(1)-adrenergic receptor associated with survival in patients with heart failure. , 2000, European heart journal.
[10] P. Karczewski,et al. Both &bgr;2- and &bgr;1-Adrenergic Receptors Mediate Hastened Relaxation and Phosphorylation of Phospholamban and Troponin I in Ventricular Myocardium of Fallot Infants, Consistent With Selective Coupling of &bgr;2-Adrenergic Receptors to Gs-Protein , 2000 .
[11] Ernst-GeorgKrause,et al. Both β2- and β1-Adrenergic Receptors Mediate Hastened Relaxation and Phosphorylation of Phospholamban and Troponin I in Ventricular Myocardium of Fallot Infants, Consistent With Selective Coupling of β2-Adrenergic Receptors to Gs-Protein , 2000 .
[12] B. Fu,et al. The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects. , 2000, Clinical science.
[13] R. Hetzer,et al. β1-Adrenoceptor gene variations: a role in idiopathic dilated cardiomyopathy? , 2000, Journal of Molecular Medicine.
[14] J. Granneman,et al. β1-Adrenergic Receptors Mediate β3-Adrenergic-Independent Effects of CGP 12177 in Brown Adipose Tissue , 2000 .
[15] P. Molenaar,et al. Putative β4‐adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (−)‐[3H]‐CGP 12177 binding , 1999, British journal of pharmacology.
[16] R. Summers,et al. Desensitization and resensitization of β1‐ and putative β4‐adrenoceptor mediated responses occur in parallel in a rat model of cardiac failure , 1999 .
[17] U. Ravens,et al. β4-Adrenoceptors are more effective than β1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes , 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.
[18] L. Tiret,et al. Characterization of a Unique Genetic Variant in the β1-adrenoceptor Gene and Evaluation of its Role in Idiopathic Dilated Cardiomyopathy , 1999 .
[19] D. A. Mason,et al. A Gain-of-function Polymorphism in a G-protein Coupling Domain of the Human β1-Adrenergic Receptor* , 1999, The Journal of Biological Chemistry.
[20] S. Ball,et al. Common polymorphisms of β1-adrenoceptor: identification and rapid screening assay , 1999, The Lancet.
[21] Ernst-GeorgKrause,et al. Activation of β2-Adrenergic Receptors Hastens Relaxation and Mediates Phosphorylation of Phospholamban, Troponin I, and C-Protein in Ventricular Myocardium From Patients With Terminal Heart Failure , 1999 .
[22] P. Karczewski,et al. Activation of (cid:98) 2 -Adrenergic Receptors Hastens Relaxation and Mediates Phosphorylation of Phospholamban, Troponin I, and C-Protein in Ventricular Myocardium From Patients With Terminal Heart Failure , 1998 .
[23] P. Molenaar,et al. Validity of (−)‐[3H]‐CGP 12177A as a radioligand for the ‘putative β4‐adrenoceptor’ in rat atrium , 1998, British journal of pharmacology.
[24] P. Molenaar,et al. Modulation of human cardiac function through 4 β-adrenoceptor populations , 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.
[25] J. Lynham,et al. Stimulation of cyclic AMP‐dependent protein kinase in rat atria by (–;)‐CGP 12177 through an atypical β‐adrenoceptor , 1997, British journal of pharmacology.
[26] P. Molenaar,et al. Differences between the third cardiac β‐adrenoceptor and the colonic β3‐adrenoceptor in the rat , 1996 .
[27] L. Sanders,et al. Chronic β1-adrenoceptor blockade sensitises the H1 and H2 receptor systems in human atrium: role of cyclic nucleotides , 1996, Naunyn-Schmiedeberg's Archives of Pharmacology.
[28] A. Kaumann. (—)‐CGP 12177‐induced increase of human atrial contraction through a putative third β‐adrenoceptor , 1996, British journal of pharmacology.
[29] R. Hershberger,et al. Pharmacologic and hemodynamic effects of combined beta-agonist stimulation and phosphodiesterase inhibition in the failing human heart. , 1995, Chest.
[30] O. Brodde. Beta 1- and beta 2-adrenoceptors in the human heart: properties, function, and alterations in chronic heart failure. , 1991, Pharmacological reviews.
[31] M. Brown,et al. Selective j31-Adrenoceptor Blockade Enhances Positive Inotropic Responses toEndogenous Catecholamines Mediated Through j2-Adrenoceptors inHumanAtrial Myocardium , 1990 .
[32] A. Kaumann. Is there a third heart β-adrenoceptor? , 1989 .
[33] M. Brown,et al. A comparison of the effects of adrenaline and noradrenaline on human heart: the role of beta 1- and beta 2-adrenoceptors in the stimulation of adenylate cyclase and contractile force. , 1989, European heart journal.
[34] Shirley A. Miller,et al. A simple salting out procedure for extracting DNA from human nucleated cells. , 1988, Nucleic acids research.
[35] S. Jamieson,et al. Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure. , 1986, Circulation research.
[36] S. Jamieson,et al. β1‐ and β2‐Adrenergic‐Receptor Subpopulations in Nonfailing and Failing Human Ventricular Myocardium: Coupling of Both Receptor Subtypes to Muscle Contraction and Selective β1‐Receptor Down‐Regulation in Heart Failure , 1986 .
[37] A. Kaumann,et al. The affinity of (−)-propranolol for β1- and β1-autoreceptors of human heart , 1985, Naunyn-Schmiedeberg's Archives of Pharmacology.
[38] M. Lohse,et al. Abolition of (-)-CGP 12177-evoked cardiostimulation in double β1/β2-adrenoceptor knockout mice. Obligatory role of β1-adrenoceptors for putative β4-adrenoceptor pharmacology , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.
[39] A. Kaumann. Gs protein-coupled receptors in human heart , 2000 .
[40] D. A. Mason,et al. Racial differences in the frequencies of cardiac β1‐adrenergic receptor polymorphisms: Analysis of c145A>G and c1165G>C , 1999, Human mutation.
[41] F. Müller,et al. Phosphodiesterase inhibition and positive inotropy in failing human myocardium. , 1992, Basic Research in Cardiology.
[42] P. Winship,et al. POLYMORPHISM , 1945, Physics and Chemistry of Molecular Assemblies.
[43] A. Kaumann,et al. The affinity of (-)-propranolol for beta 1- and beta 2-adrenoceptors of human heart. Differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (-)-noradrenaline and (-)-adrenaline. , 1985, Naunyn-Schmiedeberg's archives of pharmacology.