The impacts of aviation emissions on human health through changes in air quality and UV irradiance

World-wide demand for air transportation is rising steadily. The air transportation network may be limited by aviation’s growing environmental impacts. These impacts take the form of climate impacts, noise impacts, and health impacts, the latter of which are addressed in this thesis. Aircraft emissions released into the atmosphere have an impact on human health. In the context of assessing the environmental impacts of aviation-related policies, costs and benefits on human health must be considered. Two different models were developed as tools to assess the impacts of aircraft emissions on human health. The first model estimates the changes in skin cancer incidences and mortalities due to changes in ozone column caused by aircraft NOx emissions. The second model estimates changes in health endpoints related to changes in ambient concentrations of particulate matter (PM2.5) by estimating changes in elemental carbon, primary and secondary organic PM, secondary sulfates, and secondary nitrates. The air quality model discussed herein is the second iteration in the development of a response surface model (RSM) based on a set of 25 simulations done with the Community Multiscale Air Quality model (CMAQ), a more complex atmospheric chemistry model. The increase in adult premature mortalities in the U.S. caused by air quality impacts of aviation emissions in year 2005 is estimated at 210 deaths per year (90% confidence interval: 130 340). This considers only those emissions that occur below 3000 feet above ground level as is consistent with

[1]  R. McKenzie,et al.  Changes in biologically active ultraviolet radiation reaching the Earth's surface. , 1998, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[2]  Natalie Dobie,et al.  Procedures for Emission Inventory Preparation: Volume IV: Mobile Sources , 1992 .

[3]  Dimitri N. Mavris,et al.  Architecture Study for the Aviation Environmental Portfolio Management Tool , 2006 .

[4]  Martin A. Weinstock,et al.  Nonmelanoma Skin Cancer Mortality , 1996 .

[5]  Douglas Allaire,et al.  Uncertainty assessment of complex models with application to aviation environmental systems , 2009 .

[6]  M. Thayer,et al.  The benefits of reducing the incidence of nonmelanoma skin cancers: A defensive expenditures approach , 1990 .

[7]  J. Scotto,et al.  Indications of future decreasing trends in skin‐melanoma mortality among whites in the United States , 1991, International journal of cancer.

[8]  E. Maibach,et al.  Economic Evaluation of the US Environmental Protection Agency's SunWise Program: Sun Protection Education for Young Children , 2008, Pediatrics.

[9]  S. Madronich,et al.  Trends in UV radiation , 1996 .

[10]  D. Byun,et al.  Review of the Governing Equations, Computational Algorithms, and Other Components of the Models-3 Community Multiscale Air Quality (CMAQ) Modeling System , 2006 .

[11]  K. Limaye,et al.  Nonmelanoma Skin Cancer: Part 2 , 2011 .

[12]  U. Epa Air Quality Criteria for Particulate Matter , 1996 .

[13]  J. Penner,et al.  Aviation and the Global Atmosphere , 1999 .

[14]  O. Jolliet,et al.  Defining intake fraction. , 2002, Environmental science & technology.

[15]  Julien Joseph Rojo,et al.  Future trends in local air quality impacts of aviation , 2007 .

[16]  A. Zuckerman,et al.  IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , 1995, IARC monographs on the evaluation of carcinogenic risks to humans.

[17]  E. D. Smith,et al.  Cost of Nonmelanoma Skin Cancer Treatment in the United States , 2001, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[18]  J. Longstreth,et al.  Melanoma mortality and exposure to ultraviolet radiation: An empirical relationship , 1991 .

[19]  T. Fears,et al.  Incidence of Nonmelanoma Skin Cancer in the United States. , 1984 .

[20]  F. D. de Gruijl,et al.  UV‐induced skin cancer in a hairless mouse model , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

[21]  R. Setlow Spectral regions contributing to melanoma: a personal view. , 1999, The journal of investigative dermatology. Symposium proceedings.

[22]  M. Herlyn,et al.  Recent advances in melanoma biology. , 2004, The oncologist.

[23]  S. Leeder,et al.  A population based study , 1993, The Medical journal of Australia.

[24]  W. Schoepp,et al.  The RAINS Model. Documentation of the model approachprepared for the RAINS peer review 2004 , 2004 .

[25]  Z. Šesták,et al.  Environmental Effects of Ozone Depletion: 1998 Assessment , 2001, Photosynthetica.

[26]  Steven R H Barrett,et al.  Global mortality attributable to aircraft cruise emissions. , 2010, Environmental science & technology.

[27]  R. Setlow The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[28]  Steven R Feldman,et al.  Treatment Patterns and Cost of Nonmelanoma Skin Cancer Management , 2006, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[29]  M. Weinstock,et al.  Nonmelanoma skin cancer mortality. A population-based study. , 1991, Archives of dermatology.

[30]  R. Burnett,et al.  Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. , 2002, JAMA.

[31]  S. Madronich Implications of recent total atmospheric ozone measurements for biologically active ultraviolet radiation reaching the Earth's surface , 1992 .

[32]  U. Epa,et al.  Regulatory Impact Analysis for the Final Clean Air Interstate Rule , 2005 .

[33]  Genital and nongenital nonmelanoma skin cancer: more epidemiological studies are needed. , 2007, The Journal of investigative dermatology.

[34]  Sasha Madronich,et al.  UV radiation in the natural and perturbed atmosphere , 1993 .

[35]  A. Nenes,et al.  ISORROPIA: A New Thermodynamic Equilibrium Model for Multiphase Multicomponent Inorganic Aerosols , 1998 .

[36]  Jean Y. Tang,et al.  Novel Hedgehog pathway targets against basal cell carcinoma. , 2007, Toxicology and applied pharmacology.

[37]  David Pearce,et al.  VALUING RISKS TO LIFE AND HEALTH Towards Consistent Transfer Estimates in the European Union and Accession States , 2000 .

[38]  D. Byun Science algorithms of the EPA Models-3 community multi-scale air quality (CMAQ) modeling system , 1999 .

[39]  P. Crutzen A discussion of the chemistry of some minor constituents in the stratosphere and troposphere , 1973 .

[40]  M. Karagas,et al.  Increase in incidence rates of basal cell and squamous cell skin cancer in New Hampshire, USA , 1999, International journal of cancer.

[41]  D. Fahey,et al.  Ozone production in the rural troposphere and the implications for regional and global ozone distributions , 1987 .

[42]  S. Madronich,et al.  Skin cancer and UV radiation , 1993, Nature.

[43]  A. Ziegler,et al.  Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[44]  B. Thiers Ultraviolet Radiation and Skin Cancer: Molecular Mechanisms , 2006 .

[45]  M. Gauss,et al.  Impact of aircraft NO x emissions on the atmosphere – tradeoffs to reduce the impact , 2005 .

[46]  J. Goldsmith Effects on Human Health , 1986 .

[47]  S. Pandis,et al.  Effect of NOx on secondary organic aerosol concentrations. , 2008, Environmental science & technology.

[48]  Keith P. Shine,et al.  Impact of perturbations to nitrogen oxide emissions from global aviation , 2008 .

[49]  J. Halton On the efficiency of certain quasi-random sequences of points in evaluating multi-dimensional integrals , 1960 .

[50]  Martin A Weinstock,et al.  Nonmelanoma skin cancer mortality (1988-2000): the Rhode Island follow-back study. , 2004, Archives of dermatology.

[51]  David S. Lee,et al.  Transport impacts on atmosphere and climate: Metrics , 2010 .

[52]  Anu Vedantham,et al.  Aviation and the Global Atmosphere: A Special Report of IPCC Working Groups I and III , 1999 .

[53]  J. C. van der Leun,et al.  Estimate of the wavelength dependency of ultraviolet carcinogenesis in humans and its relevance to the risk assessment of a stratospheric ozone depletion. , 1994 .

[54]  U. Epa,et al.  Final Regulatory Impact Analysis: Control of Emissions from Nonroad Diesel Engines , 1998 .

[55]  J. Simon,et al.  A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[56]  Gert Kelfkens,et al.  OZONE DEPLETION AND INCREASE IN ANNUAL CARCINOGENIC ULTRAVIOLET DOSE , 1990, Photochemistry and photobiology.

[57]  F. Noonan,et al.  The effects on human health from stratospheric ozone depletion and its interactions with climate change , 2007, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[58]  John D. Spengler,et al.  Spatial patterns of mobile source particulate matter emissions-to-exposure relationships across the United States , 2007 .

[59]  C. Wey Human Health Effects of Ozone Depletion From Stratospheric Aircraft , 2001 .

[60]  T. Dragani,et al.  Libri Ricevuti: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , 1992 .

[61]  A. Mona,et al.  Ultraviolet carcinogenesis in nonmelanoma skin cancer. Part I: incidence rates in relation to geographic locations and in migrant populations. , 2004 .

[62]  Tudor Maşek,et al.  A response surface model of the air quality impacts of aviation , 2008 .

[63]  F. Gruijl,et al.  Reply to the ‘Comment on “The effects on human health from stratospheric ozone depletion and its interactions with climate change”’ by W. B. Grant, J. Moan and J. Reichrath, Photochem. Photobiol. Sci., 2007, b6, DOI: 10.1039/b705482c , 2007 .

[64]  T. Fears,et al.  Estimating increases in skin cancer morbidity due to increases in ultraviolet radiation exposure. , 1983, Cancer investigation.

[65]  E. Lebret,et al.  Aircraft noise around a large international airport and its impact on general health and medication use , 2004, Occupational and Environmental Medicine.

[66]  Christopher J Sequeira An assessment of the health implications of aviation emissions regulations , 2008 .