GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

[1]  Samuel W. Cushman,et al.  Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells , 2005, The Journal of cell biology.

[2]  K. Aoki,et al.  Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells. , 2005, Molecular biology of the cell.

[3]  M. Skalski,et al.  Inhibition of SNARE-mediated membrane traffic impairs cell migration. , 2005, Experimental cell research.

[4]  W. Guggino,et al.  Regulation of Cystic Fibrosis Transmembrane Regulator Trafficking and Protein Expression by a Rho Family Small GTPase TC10* , 2005, Journal of Biological Chemistry.

[5]  G. Rutter,et al.  Mechanisms of Dense Core Vesicle Recapture following “Kiss and Run” (“Cavicapture”) Exocytosis in Insulin-secreting Cells* , 2004, Journal of Biological Chemistry.

[6]  C. Coban,et al.  Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 , 2004, Nature Immunology.

[7]  D. Bredt,et al.  AMPA Receptor Synaptic Targeting Regulated by Stargazin Interactions with the Golgi-Resident PDZ Protein nPIST , 2004, The Journal of Neuroscience.

[8]  D. Steiner,et al.  Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[9]  M. Matsuda,et al.  RalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells. , 2004, Molecular biology of the cell.

[10]  J. Rothman,et al.  Imaging single membrane fusion events mediated by SNARE proteins. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[11]  K. Aoki,et al.  Spatio-temporal Regulation of Rac1 and Cdc42 Activity during Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells* , 2004, Journal of Biological Chemistry.

[12]  M. Matsuda,et al.  Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. , 2003, Molecular biology of the cell.

[13]  M. White,et al.  Ral GTPases Regulate Exocyst Assembly through Dual Subunit Interactions* , 2003, Journal of Biological Chemistry.

[14]  A. Saltiel,et al.  Insulin Signaling in Microdomains of the Plasma Membrane , 2003, Traffic.

[15]  Christopher G. Burd,et al.  The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization , 2003, The Journal of cell biology.

[16]  D. Hirsch,et al.  Arf and its many interactors. , 2003, Current opinion in cell biology.

[17]  M. Matsuda,et al.  Activity of Rho-family GTPases during cell division as visualized with FRET-based probes , 2003, The Journal of cell biology.

[18]  M. Kanzaki,et al.  Insulin Signaling: GLUT4 Vesicles Exit via the Exocyst , 2003, Current Biology.

[19]  G. Bokoch,et al.  Facilitation of Ca2+‐dependent exocytosis by Rac1‐GTPase in bovine chromaffin cells , 2003 .

[20]  Nicole Rusk,et al.  Control of Vesicular Trafficking by Rho GTPases , 2003, Current Biology.

[21]  Alan R. Saltiel,et al.  The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin , 2003, Nature.

[22]  D. Haber,et al.  DOCK4, a GTPase Activator, Is Disrupted during Tumorigenesis , 2003, Cell.

[23]  D. Bar-Sagi,et al.  Redox-dependent downregulation of Rho by Rac , 2003, Nature Cell Biology.

[24]  M. Matsuda,et al.  Mechanism of the spatio‐temporal regulation of Ras and Rap1 , 2003, The EMBO journal.

[25]  J. Rothman,et al.  The machinery and principles of vesicle transport in the cell , 2002, Nature Medicine.

[26]  R. Schekman SEC mutants and the secretory apparatus , 2002, Nature Medicine.

[27]  M. Matsuda,et al.  Activation of Rac and Cdc42 Video Imaged by Fluorescent Resonance Energy Transfer-Based Single-Molecule Probes in the Membrane of Living Cells , 2002, Molecular and Cellular Biology.

[28]  S. Munro,et al.  Vesicle tethering complexes in membrane traffic. , 2002, Journal of cell science.

[29]  M. Kanzaki,et al.  Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes. , 2002, Molecular biology of the cell.

[30]  Wei Guo,et al.  Ras family therapy: Rab, Rho and Ral talk to the exocyst. , 2002, Trends in cell biology.

[31]  A. Saltiel,et al.  Insulin signaling pathways in time and space. , 2002, Trends in cell biology.

[32]  G. Cutting,et al.  A Golgi-associated PDZ Domain Protein Modulates Cystic Fibrosis Transmembrane Regulator Plasma Membrane Expression* , 2002, The Journal of Biological Chemistry.

[33]  T. Noda,et al.  Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. , 2001, Biochemical and biophysical research communications.

[34]  A. Miyawaki,et al.  Spatio-temporal images of growth-factor-induced activation of Ras and Rap1 , 2001, Nature.

[35]  A. Ridley Rho Proteins: Linking Signaling with Membrane Trafficking , 2001, Traffic.

[36]  Makoto Kanzaki,et al.  Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10 , 2001, Nature.

[37]  Marino Zerial,et al.  Rab proteins as membrane organizers , 2001, Nature Reviews Molecular Cell Biology.

[38]  Richard H. Scheller,et al.  SNARE-mediated membrane fusion , 2001, Nature Reviews Molecular Cell Biology.

[39]  David Michaelson,et al.  Differential Localization of Rho Gtpases in Live Cells , 2001, The Journal of cell biology.

[40]  J. Settleman,et al.  Rho family GTPases: more than simple switches. , 2000, Trends in cell biology.

[41]  F. Hughson,et al.  Membrane Tethering and Fusion in the Secretory and Endocytic Pathways , 2000, Traffic.

[42]  A. Hall,et al.  Rho GTPases and their effector proteins. , 2000, The Biochemical journal.

[43]  R. Cerione,et al.  Cdc42 and Rac Stimulate Exocytosis of Secretory Granules by Activating the Ip3/Calcium Pathway in Rbl-2h3 Mast Cells , 2000, The Journal of cell biology.

[44]  M. Matsuda,et al.  Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins. , 1999, Biochimica et biophysica acta.

[45]  P. Chavrier,et al.  The role of ARF and Rab GTPases in membrane transport. , 1999, Current opinion in cell biology.

[46]  J. Goldberg Structural and Functional Analysis of the ARF1–ARFGAP Complex Reveals a Role for Coatomer in GTP Hydrolysis , 1999, Cell.

[47]  P. Novick,et al.  The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis , 1999, The EMBO journal.

[48]  A. Parmeggiani,et al.  EF-Tu, a GTPase odyssey. , 1998, Biochimica et biophysica acta.

[49]  G. Joberty,et al.  Distinct cellular effects and interactions of the Rho-family GTPase TC10 , 1998, Current Biology.

[50]  M. Bretscher,et al.  Membrane traffic during cell locomotion. , 1998, Current opinion in cell biology.

[51]  W. Nelson,et al.  Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases , 1998, The Journal of cell biology.

[52]  A. Ridley,et al.  A Role for Cdc42 in Macrophage Chemotaxis , 1998, The Journal of cell biology.

[53]  L. Van Aelst,et al.  Rho GTPases and signaling networks. , 1997, Genes & development.

[54]  P. Novick,et al.  The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. , 1996, The EMBO journal.

[55]  J. Norman,et al.  The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways. , 1996, Molecular biology of the cell.

[56]  M. Shibuya,et al.  DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane , 1996, Molecular and cellular biology.

[57]  Y. Jan,et al.  Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion. , 1994, Genes & development.

[58]  John G. Collard,et al.  Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins , 1994, Cell.

[59]  M. Shibuya,et al.  C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[60]  M. Moran,et al.  Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases , 1990, Nature.

[61]  A. Iwamatsu,et al.  The exocyst complex binds the small GTPase RalA to mediate filopodia formation , 2002, Nature Cell Biology.

[62]  C. Rossé,et al.  The exocyst is a Ral effector complex , 2002, Nature Cell Biology.

[63]  K. Mikoshiba,et al.  A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications , 2002, Nature Biotechnology.

[64]  K. Kaibuchi,et al.  Small GTP-binding proteins. , 1992, International review of cytology.