Impaired immune and acute-phase responses in interleukin-6-deficient mice

[1]  G. Yancopoulos,et al.  The alphas, betas, and kinases of cytokine receptor complexes , 1993, Cell.

[2]  R. Zinkernagel,et al.  Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes , 1993, Nature.

[3]  T. Mak,et al.  Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection , 1993, Cell.

[4]  A. Ramsay,et al.  A case for cytokines as effector molecules in the resolution of virus infection. , 1993, Immunology today.

[5]  R. Simmons,et al.  Reactive nitrogen intermediates suppress the primary immunologic response to Listeria. , 1993, Journal of immunology.

[6]  A. Bradley,et al.  Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. , 1993, Science.

[7]  R. Zinkernagel,et al.  Immune response in mice that lack the interferon-gamma receptor. , 1993, Science.

[8]  E. Unanue,et al.  Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. , 1993, Journal of immunology.

[9]  S. Akira,et al.  Interleukin-6 and its receptor: a paradigm for cytokines. , 1992, Science.

[10]  P. Morrissey,et al.  Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[11]  D. Solter,et al.  Gene expression during preimplantation mouse development. , 1992, Genes & development.

[12]  L. Moldawer,et al.  Type I IL-1 receptor blockade exacerbates murine listeriosis. , 1992, Journal of immunology.

[13]  M. Eichelberger,et al.  Roles of alpha beta and gamma delta T cell subsets in viral immunity. , 1992, Annual review of immunology.

[14]  S. Kaufmann,et al.  Immunity to intracellular bacteria. , 1992, Memorias do Instituto Oswaldo Cruz.

[15]  T. Kündig,et al.  Antiviral protection by CD8+ versus CD4+ T cells. CD8+ T cells correlating with cytotoxic activity in vitro are more efficient in antivaccinia virus protection than CD4-dependent IL. , 1991, Journal of immunology.

[16]  F. Liew,et al.  Nonspecific defence mechanism: the role of nitric oxide. , 1991, Immunology today.

[17]  J. Snick,et al.  Interleukin-6: an overview. , 1990, Annual review of immunology.

[18]  R. Zinkernagel,et al.  Impaired Generation of Anti‐Viral Cytotoxicity against Lymphocytic Choriomeningitis and Vaccinia Virus in Mice Treated with CD4‐Specific Monoclonal Antibody , 1989, Scandinavian journal of immunology.

[19]  J. Miyazaki,et al.  IgG1 plasmacytosis in interleukin 6 transgenic mice. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[20]  T. Kishimoto,et al.  The biology of interleukin-6. , 1989, Blood.

[21]  C. Nathan,et al.  Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. , 1988, Journal of immunology.

[22]  C. Uyttenhove,et al.  T cell growth and differentiation induced by interleukin-HP1/IL-6, the murine hybridoma/plasmacytoma growth factor , 1988, The Journal of experimental medicine.

[23]  T. Hirano,et al.  B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes , 1988, The Journal of experimental medicine.

[24]  H. Baumann [481 Electrophoretic analysis of acute-phase plasma proteins , 1988 .

[25]  C. Uyttenhove,et al.  Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[26]  M. Glibetić,et al.  Mouse α1-protease inhibitor is not an acute phase reactant , 1986, Archives of Biochemistry and Biophysics.

[27]  R M Zinkernagel,et al.  Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[28]  R. North Opinions: The Concept of the Activated Macrophage , 1978 .

[29]  R. Blanden,et al.  Cell‐Mediated Immunity to Bacterial Infection in the Mouse. Thymus‐Derived Cells as Effectors of Acquired Resistance to Listeria monocytogenes , 1972, Scandinavian journal of immunology.