Purpose in life promotes resilience to age-related brain burden in middle-aged adults

[1]  Á. Pascual-Leone,et al.  Associations between repetitive negative thinking and resting-state network segregation among healthy middle-aged adults , 2022, Frontiers in Aging Neuroscience.

[2]  S. Pilling,et al.  Associations between psychological intervention for anxiety disorders and risk of dementia: a prospective cohort study using national health-care records data in England. , 2022, The Lancet. Healthy longevity.

[3]  L. Barnes,et al.  Negative and Positive Psychosocial Factors in Relation to Cognitive Health in Older African Americans , 2022, Innovation in aging.

[4]  Á. Pascual-Leone,et al.  Sense of Coherence Mediates the Relationship Between Cognitive Reserve and Cognition in Middle-Aged Adults , 2022, Frontiers in Psychology.

[5]  Eric S. Kim,et al.  Ikigai and subsequent health and wellbeing among Japanese older adults: Longitudinal outcome-wide analysis , 2022, The Lancet regional health. Western Pacific.

[6]  J. Sepulcre,et al.  Connectomic-genetic signatures in the cerebral small vessel disease , 2022, Neurobiology of Disease.

[7]  R. Saunders,et al.  Positive psychological constructs and association with reduced risk of mild cognitive impairment and dementia in older adults: A systematic review and meta-analysis , 2022, Ageing Research Reviews.

[8]  E. Luders,et al.  Reduced age-related gray matter loss in the subgenual cingulate cortex in long-term meditators , 2021, Brain Imaging and Behavior.

[9]  A. Fagan,et al.  Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. , 2021, Brain : a journal of neurology.

[10]  N. Scarmeas,et al.  Mediterranean diet and risk for dementia and cognitive decline in a Mediterranean population , 2021, Journal of the American Geriatrics Society.

[11]  J. González-Mora,et al.  Larger whole brain grey matter associated with long-term Sahaja Yoga Meditation: A detailed area by area comparison , 2020, PloS one.

[12]  Klaus P. Ebmeier,et al.  Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline—Results From the Lifebrain Consortium , 2020, Cerebral cortex.

[13]  World Population Ageing 2019 , 2020 .

[14]  Naaheed Mukadam,et al.  Dementia prevention, intervention, and care: 2020 report of the Lancet Commission , 2020, The Lancet.

[15]  Eric S. Kim,et al.  Sense of purpose in life and five health behaviors in older adults. , 2020, Preventive medicine.

[16]  G. Chételat,et al.  Repetitive negative thinking is associated with amyloid, tau, and cognitive decline , 2020, Alzheimer's & dementia : the journal of the Alzheimer's Association.

[17]  Cassidy M. Fiford,et al.  CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease , 2020, Neurobiology of Aging.

[18]  Á. Pascual-Leone,et al.  The Barcelona Brain Health Initiative: Cohort description and first follow-up , 2020, PloS one.

[19]  Nicole M. Armstrong,et al.  Late-Life Physical and Cognitive Activities Independently Contribute to Brain and Cognitive Resilience. , 2020, Journal of Alzheimer's disease : JAD.

[20]  C. Jack,et al.  Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults , 2020, Neurology.

[21]  Eric Westman,et al.  Predicting Fazekas scores from automatic segmentations of white matter signal abnormalities , 2020, Aging.

[22]  Klaus P. Ebmeier,et al.  Self-reported sleep relates to hippocampal atrophy across the adult lifespan: results from the Lifebrain consortium , 2019, Sleep.

[23]  M. Braskie,et al.  White matter hypointensities and hyperintensities have equivalent correlations with age and CSF β‐amyloid in the nondemented elderly , 2019, Brain and behavior.

[24]  C. Barnes,et al.  Brain reserve, cognitive reserve, compensation, and maintenance: operationalization, validity, and mechanisms of cognitive resilience , 2019, Neurobiology of Aging.

[25]  D. Margulies,et al.  An improved neuroanatomical model of the default-mode network reconciles previous neuroimaging and neuropathological findings , 2019, Communications Biology.

[26]  Charles D. Smith,et al.  White Matter Hyperintensity Regression: Comparison of Brain Atrophy and Cognitive Profiles with Progression and Stable Groups , 2019, Brain sciences.

[27]  A. Mondul,et al.  Association Between Life Purpose and Mortality Among US Adults Older Than 50 Years , 2019, JAMA network open.

[28]  Bratislav Misic,et al.  Loneliness and meaning in life are reflected in the intrinsic network architecture of the brain , 2019, Social cognitive and affective neuroscience.

[29]  Z. Bai,et al.  Acceptance and Commitment Therapy (ACT) to reduce depression: A systematic review and meta-analysis. , 2019, Journal of affective disorders.

[30]  A. Hofman,et al.  Inflammatory markers and the risk of dementia and Alzheimer's disease: A meta-analysis , 2018, Alzheimer's & Dementia.

[31]  C. DeCarli,et al.  Circulating cortisol and cognitive and structural brain measures , 2018, Neurology.

[32]  Alvaro Pascual-Leone,et al.  The Barcelona Brain Health Initiative: A Cohort Study to Define and Promote Determinants of Brain Health , 2018, Front. Aging Neurosci..

[33]  Miia Kivipelto,et al.  Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease , 2018, Nature Reviews Neurology.

[34]  J. Vos,et al.  The effects of psychological meaning-centered therapies on quality of life and psychological stress: A metaanalysis , 2018, Palliative and Supportive Care.

[35]  Y. Stern,et al.  Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance , 2018, Alzheimer's & Dementia.

[36]  W. Lichtenthal,et al.  Individual meaning‐centered psychotherapy for the treatment of psychological and existential distress: A randomized controlled trial in patients with advanced cancer , 2018, Cancer.

[37]  Á. Pascual-Leone,et al.  Meaning in life: resilience beyond reserve , 2018, Alzheimer's & Dementia.

[38]  Prashanthi Vemuri,et al.  Resistance vs resilience to Alzheimer disease , 2018, Neurology.

[39]  Hwajung Choi,et al.  Association Between Purpose in Life and Glucose Control Among Older Adults. , 2018, Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.

[40]  H. Völzke,et al.  Regional tract-specific white matter hyperintensities are associated with patterns of aging-related brain atrophy via vascular risk factors, but also independently , 2018, Alzheimer's & dementia.

[41]  Gagan S Wig,et al.  Segregated Systems of Human Brain Networks , 2017, Trends in Cognitive Sciences.

[42]  Brennan R. Payne,et al.  Purpose in life and cognitive functioning in adulthood , 2017, Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.

[43]  G. Rauchs,et al.  Reduced age-associated brain changes in expert meditators: a multimodal neuroimaging pilot study , 2017, Scientific Reports.

[44]  N. Scarmeas,et al.  Mediterranean diet and cognitive health: Initial results from the Hellenic Longitudinal Investigation of Ageing and Diet , 2017, PloS one.

[45]  Yuri Miyamoto,et al.  Psychological Resources and Glucoregulation in Japanese Adults: Findings From MIDJA , 2017, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[46]  J. Bean,et al.  Rey Auditory Verbal Learning Test, Rey AVLT , 2017 .

[47]  G. Chételat,et al.  Distinct effects of late adulthood cognitive and physical activities on gray matter volume , 2017, Brain Imaging and Behavior.

[48]  C. Reekum,et al.  Purposeful Engagement, Healthy Aging, and the Brain , 2016, Current Behavioral Neuroscience Reports.

[49]  K. Arfanakis,et al.  NEUROPATHOLOGIC CORRELATES OF WHITE MATTER HYPERINTENSITIES IN A COMMUNITY COHORT OF OLDER ADULTS , 2016, Alzheimer's & Dementia.

[50]  Christopher G. Davey,et al.  Mapping the self in the brain's default mode network , 2016, NeuroImage.

[51]  Christos Davatzikos,et al.  White matter hyperintensities and imaging patterns of brain ageing in the general population. , 2016, Brain : a journal of neurology.

[52]  G. Chételat,et al.  Cognitive reserve and lifestyle: moving towards preclinical Alzheimer’s disease , 2015, Front. Aging Neurosci..

[53]  J. Schneider,et al.  Purpose in Life and Cerebral Infarcts in Community-Dwelling Older People , 2015, Stroke.

[54]  K. Zakzanis,et al.  The neuropsychological profile of vascular cognitive impairment not demented: a meta-analysis. , 2015, Journal of neuropsychology.

[55]  Barry Rosenfeld,et al.  Meaning-centered group psychotherapy: an effective intervention for improving psychological well-being in patients with advanced cancer. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[56]  Diana I. Tamir,et al.  Mental simulation and meaning in life. , 2015, Journal of personality and social psychology.

[57]  Denise C. Park,et al.  Decreased segregation of brain systems across the healthy adult lifespan , 2014, Proceedings of the National Academy of Sciences.

[58]  Eric S. Kim,et al.  Purpose in life and use of preventive health care services , 2014, Proceedings of the National Academy of Sciences.

[59]  S. Irwin,et al.  Meaning-Centered Psychotherapy: A Form of Psychotherapy for Patients With Cancer , 2014, Current Psychiatry Reports.

[60]  John O. Willis,et al.  Wechsler Adult Intelligence Scale–Fourth Edition , 2014 .

[61]  C. Ryff.  Psychological Well-Being Revisited: Advances in the Science and Practice of Eudaimonia , 2013, Psychotherapy and Psychosomatics.

[62]  Penny Dade,et al.  Encyclopedia of Autism Spectrum Disorders , 2013 .

[63]  Joshua A. Hicks,et al.  The Experience of Meaning in Life , 2013 .

[64]  Eric S. Kim,et al.  Purpose in life and reduced risk of myocardial infarction among older U.S. adults with coronary heart disease: a two-year follow-up , 2013, Journal of Behavioral Medicine.

[65]  David A Bennett,et al.  Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age. , 2012, Archives of general psychiatry.

[66]  M. Quintana,et al.  Spanish normative studies in a young adult population (NEURONORMA young adults project): Methods and characteristics of the sample , 2012 .

[67]  M. Greicius,et al.  Decoding subject-driven cognitive states with whole-brain connectivity patterns. , 2012, Cerebral cortex.

[68]  Y. B. Wah,et al.  Power comparisons of Shapiro-Wilk , Kolmogorov-Smirnov , Lilliefors and Anderson-Darling tests , 2011 .

[69]  D. Bennett,et al.  Purpose in life is associated with a reduced risk of incident disability among community-dwelling older persons. , 2010, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[70]  H. Markus,et al.  The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis , 2010, BMJ : British Medical Journal.

[71]  David A Bennett,et al.  Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. , 2010, Archives of general psychiatry.

[72]  Akiko Tamakoshi,et al.  Associations of ikigai as a positive psychological factor with all-cause mortality and cause-specific mortality among middle-aged and elderly Japanese people: findings from the Japan Collaborative Cohort Study. , 2009, Journal of psychosomatic research.

[73]  David A Bennett,et al.  Purpose in Life Is Associated With Mortality Among Community-Dwelling Older Persons , 2009, Psychosomatic medicine.

[74]  Sandra Black,et al.  Understanding White Matter Disease: Imaging-Pathological Correlations in Vascular Cognitive Impairment , 2009, Stroke.

[75]  T. Golde.  Alzheimer's Research & Therapy , 2009 .

[76]  D. Schacter,et al.  The Brain's Default Network , 2008, Annals of the New York Academy of Sciences.

[77]  Justin L. Vincent,et al.  Disruption of Large-Scale Brain Systems in Advanced Aging , 2007, Neuron.

[78]  A. Hofman,et al.  Incidental findings on brain MRI in the general population. , 2007, The New England journal of medicine.

[79]  Burton H Singer,et al.  Plasma interleukin-6 and soluble IL-6 receptors are associated with psychological well-being in aging women. , 2007, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[80]  Richard J. Davidson,et al.  Psychological Well-Being and Ill-Being: Do They Have Distinct or Mirrored Biological Correlates? , 2006, Psychotherapy and Psychosomatics.

[81]  S. Rubin,et al.  Inflammatory markers and cognition in well-functioning African-American and white elders , 2003, Neurology.

[82]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[83]  U. Lundberg,et al.  Is low cortisol release an indicator of positive health , 2002 .

[84]  A Hofman,et al.  Hypertension and cerebral white matter lesions in a prospective cohort study. , 2002, Brain : a journal of neurology.

[85]  C. Keyes,et al.  The structure of psychological well-being revisited. , 1995, Journal of personality and social psychology.

[86]  Carol D. Ryff,et al.  Beyond Ponce de Leon and Life Satisfaction: New Directions in Quest of Successful Ageing , 1989 .

[87]  C. Ryff.  Happiness is everything, or is it? Explorations on the meaning of psychological well-being. , 1989 .

[88]  S. Shapiro,et al.  An Analysis of Variance Test for Normality (Complete Samples) , 1965 .

[89]  T. Hora,et al.  Existential psychotherapy. , 1962, Current psychiatric therapies.