Multiwall carbon nanotubes decorated with NiFe2O4 magnetic nanoparticles, a new catalyst for voltammetric determination of cefixime.

Multiwall carbon nanotubes were decorated with synthesized NiFe(2)O(4) magnetic nanoparticles. The new materials were characterized with different techniques such as transform infrared spectroscopy, transmission electron microscopy, atomic force microscopy and electrochemical impedance spectroscopy. The multiwall carbon nanotubes decorated with NiFe(2)O(4) magnetic nanoparticles was used as a new mediator for the voltammetric determination of cefixime. Under the optimum conditions at pH 8.0, the oxidation of cefixime was occurred at 850 mV at the surface of the modified electrode. Linear sweep voltammetry exhibited two wide linear dynamic ranges of 0.1-100 and 100-600 μmol L(-1) cefixime. The detection limit was found to be 0.02 μmol L(-1) cefixime. Finally, the modified electrode showed good sensitivity, selectivity and stability for the determination of cefixime in real samples.

[1]  A. MacGowan,et al.  HPLC assay of cefixime in serum and CSF. , 1993, The Journal of antimicrobial chemotherapy.

[2]  S. Maensiri,et al.  A simple route to synthesize nickel ferrite (NiFe2O4) nanoparticles using egg white , 2007 .

[3]  Galen D. Stucky,et al.  MESOPOROUS SILICATE SEQUESTRATION AND RELEASE OF PROTEINS , 1999 .

[4]  I. Al-Momani.  Spectrophotometric determination of selected cephalosporins in drug formulations using flow injection analysis. , 2001, Journal of pharmaceutical and biomedical analysis.

[5]  S. Ozkan,et al.  Anodic voltammetric behavior and determination of cefixime in pharmaceutical dosage forms and biological fluids. , 2005, Talanta.

[6]  R. Waldron.  Infrared Spectra of Ferrites , 1955 .

[7]  K. Modi,et al.  Study of elastic behaviour of magnesium ferri aluminates , 2006 .

[8]  P. Ajayan,et al.  Applications of Carbon Nanotubes , 2001 .

[9]  Lei Zhang,et al.  A review of anode catalysis in the direct methanol fuel cell , 2006 .

[10]  Hassan Karimi-Maleh,et al.  Characterization of Mn-nanoparticles decorated organo-functionalized SiO2–Al2O3 mixed-oxide as a novel electrochemical sensor: application for the voltammetric determination of captopril , 2011 .

[11]  Jean-Jacques Delaunay,et al.  Magnetic Thin Films of Cobalt Nanocrystals Encapsulated in Graphite-Like Carbon , 1997 .

[12]  Hongjie Dai,et al.  Metal-coated carbon nanotube tips for magnetic force microscopy , 2004 .

[13]  Xiaoyan Chen,et al.  Sensitive liquid chromatography-tandem mass spectrometry method for the determination of cefixime in human plasma: application to a pharmacokinetic study. , 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[14]  S. Erkoç,et al.  Titanium coverage on a single-wall carbon nanotube: molecular dynamics simulations , 2004 .

[15]  B. Rezaei,et al.  Modified glassy carbon electrode with multiwall carbon nanotubes as a voltammetric sensor for determination of noscapine in biological and pharmaceutical samples , 2008 .

[16]  Dimitrios Gournis,et al.  Attachment of Magnetic Nanoparticles on Carbon Nanotubes and Their Soluble Derivatives , 2005 .

[17]  A. Fattah,et al.  Quantitative determination of some thiazole cephalosporins through complexation with palladium (II) chloride. , 2000, Journal of pharmaceutical and biomedical analysis.

[18]  Stanislaus S. Wong,et al.  Effect of ozonolysis on the pore structure, surface chemistry, and bundling of single-walled carbon nanotubes. , 2008, Journal of colloid and interface science.

[19]  R. F. Jardim,et al.  Recoverable rhodium nanoparticles: Synthesis, characterization and catalytic performance in hydrogenation reactions , 2008 .

[20]  Vinod K. Gupta,et al.  Fullerene-C60-modified edge plane pyrolytic graphite electrode for the determination of dexamethasone in pharmaceutical formulations and human biological fluids. , 2009, Biosensors & bioelectronics.

[21]  Jing Sun,et al.  Self-assembly of magnetite beads along multiwalled carbon nanotubes via a simple hydrothermal process , 2007 .

[22]  D. Agbaba,et al.  HPTLC determination of ceftriaxone, cefixime and cefotaxime in dosage forms. , 1998, Journal of pharmaceutical and biomedical analysis.

[23]  Piet Bergveld,et al.  Biosensors, Fundamentals and Applications : Edited by A.P.F. Turner, I. Karube and G.S. Wilson, published by Oxford Science Publications, 77 pp., ISBN 0-19-854724-2. , 1988 .

[24]  B. Rezaei,et al.  Square wave voltammetric determination of Dexamethasone on a multiwalled carbon nanotube modified pencil electrode , 2011 .

[25]  Ling Bing Kong,et al.  High microwave permittivity of multiwalled carbon nanotube composites , 2004 .

[26]  Feng-sheng Li,et al.  Synthesis of Fe3O4/CNTs magnetic nanocomposites at the liquid–liquid interface using oleate as surfactant and reactant , 2009 .

[27]  Zhu Meifang,et al.  Decoration of carbon nanotubes with iron oxide , 2006 .

[28]  Double-wall carbon nanotubes: The outer shell may pattern the structure of the inner one , 2008 .

[29]  R. Kabiri,et al.  New nanocomposites containing metal nanoparticles, carbon nanotube and polymer , 2008 .

[30]  L. Bebawy,et al.  Fluorimetric determination of some antibiotics in raw material and dosage forms through ternary complex formation with terbium (Tb(3+)). , 2003, Journal of pharmaceutical and biomedical analysis.

[31]  Zhu Meifang,et al.  Novel carbon nanotube iron oxide magnetic nanocomposites , 2006 .

[32]  T. M. Reddy,et al.  Voltammetric behavior of cefixime and cefpodoxime proxetil and determination in pharmaceutical formulations and urine. , 2003, Journal of pharmaceutical and biomedical analysis.

[33]  E. Khamis,et al.  Use of Cerium (IV) in the Spectrophotometric and Spectrofluorimetric Determinations of Penicillins and Cephalosporins in Their Pharmaceutical Preparations , 2000 .

[34]  A. Allafchian,et al.  Characterization of MgFe_2O_4 Nanoparticles as a Novel Electrochemical Sensor: Application for the Voltammetric Determination of Ciprofloxacin , 2012, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[35]  Rajeev Jain,et al.  Voltammetric determination of cefixime in pharmaceuticals and biological fluids. , 2010, Analytical biochemistry.