A mononuclear nonheme {FeNO}6 complex: synthesis and structural and spectroscopic characterization

X-ray structures of nonheme {FeNO}6 and iron(iii)-nitrito complexes bearing a tetraamido macrocyclic ligand are reported along with three different generation pathways.

[1]  N. Lehnert,et al.  Functional Mononitrosyl Diiron(II) Complex Mediates the Reduction of NO to N2O with Relevance for Flavodiiron NO Reductases. , 2017, Journal of the American Chemical Society.

[2]  N. Lehnert,et al.  Ferric Heme-Nitrosyl Complexes: Kinetically Robust or Unstable Intermediates? , 2017, Inorganic chemistry.

[3]  M. Kelm,et al.  Red Blood Cell Function and Dysfunction: Redox Regulation, Nitric Oxide Metabolism, Anemia , 2017, Antioxidants & redox signaling.

[4]  S. Kundu,et al.  Copper(II) Activation of Nitrite: Nitrosation of Nucleophiles and Generation of NO by Thiols. , 2017, Journal of the American Chemical Society.

[5]  K. Hodgson,et al.  L-Edge X-ray Absorption Spectroscopic Investigation of {FeNO}6: Delocalization vs Antiferromagnetic Coupling. , 2017, Journal of the American Chemical Society.

[6]  D. Richardson,et al.  A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity* , 2016, The Journal of Biological Chemistry.

[7]  T. Kurtikyan,et al.  Six-Coordinate Ferrous Nitrosyl Complex FeII(TTP)(PMe3)(NO) (TTP = meso-Tetra-p-tolylporphyrinato Dianion). , 2016, Inorganic chemistry.

[8]  S. DeBeer,et al.  Complete Series of {FeNO}(8), {FeNO}(7), and {FeNO}(6) Complexes Stabilized by a Tetracarbene Macrocycle. , 2016, Journal of the American Chemical Society.

[9]  C. Krebs,et al.  Structural and Spectroscopic Characterization of a High-Spin {FeNO}(6) Complex with an Iron(IV)-NO(-) Electronic Structure. , 2016, Angewandte Chemie.

[10]  H. P. Gunnlaugsson.  Spreadsheet based analysis of Mössbauer spectra , 2016 .

[11]  M. Gladwin,et al.  Strategies to increase nitric oxide signalling in cardiovascular disease , 2015, Nature Reviews Drug Discovery.

[12]  N. Lehnert,et al.  Heme-nitrosyls: electronic structure implications for function in biology. , 2015, Accounts of chemical research.

[13]  K. Karlin,et al.  Reactions of a heme-superoxo complex toward a cuprous chelate and •NO(g): CcO and NOD chemistry. , 2015, Journal of porphyrins and phthalocyanines.

[14]  T. Harrop.  New Insights on {FeNO}n (n = 7, 8) Systems as Enzyme Models and HNO Donors , 2015 .

[15]  Brian C. Sanders,et al.  NO2(-) activation and reduction to NO by a nonheme Fe(NO2)2 complex. , 2014, Journal of the American Chemical Society.

[16]  N. Lehnert,et al.  Model complexes of key intermediates in fungal cytochrome P450 nitric oxide reductase (P450nor). , 2014, Current opinion in chemical biology.

[17]  A. Schechter,et al.  A Flow Cytometric Analysis of the Inhibition of Platelet Reactivity Due to Nitrite Reduction by Deoxygenated Erythrocytes , 2014, PloS one.

[18]  M. N. Álvarez,et al.  Peroxynitrite, a potent macrophage‐derived oxidizing cytotoxin to combat invading pathogens , 2014, BioFactors.

[19]  W. Liaw,et al.  Nitrite activation to nitric oxide via one-fold protonation of iron(II)-O,O-nitrito complex: relevance to the nitrite reductase activity of deoxyhemoglobin and deoxyhemerythrin. , 2013, Journal of the American Chemical Society.

[20]  N. Lehnert,et al.  Characterization of a high-spin non-heme {FeNO}(8) complex: implications for the reactivity of iron nitroxyl species in biology. , 2013, Angewandte Chemie.

[21]  G. G. Martirosyan,et al.  Weak coordination of neutral S- and O-donor proximal ligands to a ferrous porphyrin nitrosyl. Characterization of 6-coordinate complexes at low T. , 2013, Journal of inorganic biochemistry.

[22]  J. Pereira,et al.  Nitrite reduction mediated by heme models. Routes to NO and HNO? , 2013, Journal of the American Chemical Society.

[23]  J. Pereira,et al.  Mechanisms of Nitric Oxide Reactions Mediated by Biologically Relevant Metal Centers , 2013 .

[24]  Michael D. Pluth,et al.  Reversible binding of nitric oxide to an Fe(III) complex of a tetra-amido macrocycle. , 2012, Chemical communications.

[25]  S. Lippard,et al.  Generation, translocation, and action of nitric oxide in living systems. , 2011, Chemistry & biology.

[26]  M. Gladwin,et al.  The Nitrate–Nitrite–Nitric Oxide Pathway in Mammals , 2011 .

[27]  K. Aigner,et al.  Nitrite and Nitrate in Human Health and Disease , 2011 .

[28]  K. Karlin,et al.  Bioinspired heme, heme/nonheme diiron, heme/copper, and inorganic NOx chemistry: *NO((g)) oxidation, peroxynitrite-metal chemistry, and *NO((g)) reductive coupling. , 2010, Inorganic chemistry.

[29]  J. K. Hurst,et al.  The role of nitrite ion in phagocyte function--perspectives and puzzles. , 2009, Archives of biochemistry and biophysics.

[30]  D. Richardson,et al.  The bacterial respiratory nitric oxide reductase. , 2009, Biochemical Society transactions.

[31]  W. Liaw,et al.  Dinitrosyl iron complexes (DNICs) bearing O-bound nitrito ligand: reversible transformation between the six-coordinate {Fe(NO)2}9 [(1-MeIm)2(eta(2)-ONO)Fe(NO)2] (g = 2.013) and four-coordinate {Fe(NO)2}9 [(1-MeIm)(ONO)Fe(NO)2] (g = 2.03). , 2009, Journal of the American Chemical Society.

[32]  F. Neese,et al.  Calibration of modern density functional theory methods for the prediction of 57Fe Mössbauer isomer shifts: meta-GGA and double-hybrid functionals. , 2009, Inorganic chemistry.

[33]  Anthony L. Spek,et al.  Structure validation in chemical crystallography , 2009, Acta crystallographica. Section D, Biological crystallography.

[34]  N. Lehnert,et al.  Electronic structure of six-coordinate iron(III)-porphyrin NO adducts: the elusive iron(III)-NO(radical) state and its influence on the properties of these complexes. , 2008, Journal of the American Chemical Society.

[35]  P. Dedon,et al.  Kinetic analysis of intracellular concentrations of reactive nitrogen species. , 2008, Chemical research in toxicology.

[36]  Dong Wang,et al.  (TAML)FeIV O complex in aqueous solution: synthesis and spectroscopic and computational characterization. , 2008, Inorganic chemistry.

[37]  P. Moënne‐Loccoz.  Spectroscopic characterization of heme iron-nitrosyl species and their role in NO reductase mechanisms in diiron proteins. , 2007, Natural product reports.

[38]  Keith O. Hodgson,et al.  PySpline: A Modern, Cross‐Platform Program for the Processing of Raw Averaged XAS Edge and EXAFS Data , 2007 .

[39]  Arani Chanda,et al.  Chemical and Spectroscopic Evidence for an FeV-Oxo Complex , 2007, Science.

[40]  L. Liaudet,et al.  Nitric oxide and peroxynitrite in health and disease. , 2007, Physiological reviews.

[41]  Alexei S Soares,et al.  Crystal structures of the nitrite and nitric oxide complexes of horse heart myoglobin. , 2006, Journal of inorganic biochemistry.

[42]  R. O. Poyton,et al.  Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: implications for oxygen sensing and hypoxic signaling in eukaryotes. , 2006, Cell metabolism.

[43]  K. Hodgson,et al.  Sulfur K-edge XAS and DFT calculations on nitrile hydratase: geometric and electronic structure of the non-heme iron active site. , 2006, Journal of the American Chemical Society.

[44]  Malte Kelm,et al.  The emerging biology of the nitrite anion , 2005, Nature chemical biology.

[45]  W. Zumft,et al.  Nitric oxide reductases of prokaryotes with emphasis on the respiratory, heme-copper oxidase type. , 2005, Journal of inorganic biochemistry.

[46]  P. R. Gardner.  Nitric oxide dioxygenase function and mechanism of flavohemoglobin, hemoglobin, myoglobin and their associated reductases. , 2005, Journal of inorganic biochemistry.

[47]  A. Daiber,et al.  Nitric oxide reductase (P450nor) from Fusarium oxysporum. , 2005, Journal of inorganic biochemistry.

[48]  L. Que,et al.  Nonheme FeIVO complexes that can oxidize the C-H bonds of cyclohexane at room temperature. , 2004, Journal of the American Chemical Society.

[49]  P. Mascharak,et al.  Thermally induced stoichiometric and catalytic O-atom transfer by a non-heme iron(III)-nitro complex: first example of reversible [Fe-NO]7<-->FeIII-NO2 transformation in the presence of dioxygen. , 2003, Angewandte Chemie.

[50]  M. Sibi,et al.  Enantioselective conjugate radical addition to beta-acyloxy acrylate acceptors: an approach to acetate aldol-type products. , 2003, Angewandte Chemie.

[51]  P. Mascharak,et al.  Iron nitrosyls of a pentadentate ligand containing a single carboxamide group: syntheses, structures, electronic properties, and photolability of NO. , 2003, Inorganic chemistry.

[52]  T. J. Collins.  TAML oxidant activators: a new approach to the activation of hydrogen peroxide for environmentally significant problems. , 2002, Accounts of chemical research.

[53]  B. Wittenberg,et al.  Truncated hemoglobin HbN protects Mycobacterium bovis from nitric oxide , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[54]  Ivan M Lorkovic,et al.  Mechanistic aspects of the reactions of nitric oxide with transition-metal complexes. , 2002, Chemical reviews.

[55]  D. Lee,et al.  Crystal structures of cytochrome P450nor and its mutants (Ser286-->Val, Thr) in the ferric resting state at cryogenic temperature: a comparative analysis with monooxygenase cytochrome P450s. , 2000, Journal of inorganic biochemistry.

[56]  W. Scheidt,et al.  Synthesis, Molecular Structures, and Properties of Six-Coordinate [Fe(OEP)(L)(NO)]+ Derivatives: Elusive Nitrosyl Ferric Porphyrins , 1999 .

[57]  J. Zweier,et al.  Evaluation of the magnitude and rate of nitric oxide production from nitrite in biological systems. , 1998, Archives of biochemistry and biophysics.

[58]  K. Hodgson,et al.  A Multiplet Analysis of Fe K-Edge 1s → 3d Pre-Edge Features of Iron Complexes , 1997 .

[59]  L. Ignarro.  3 – Nitric Oxide as a Communication Signal in Vascular and Neuronal Cells , 1996 .

[60]  A. Becke.  Density-functional thermochemistry. III. The role of exact exchange , 1993 .

[61]  K. Hodgson,et al.  X-ray absorption, Moessbauer, and EPR studies of the dinuclear iron center in the hydroxylase component of methane monooxygenase , 1991 .

[62]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[63]  K. Suslick,et al.  Photochemical Reduction of Nitrate and Nitrite by Manganese and Iron Porphyrins , 1991 .

[64]  B. Freeman,et al.  Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[65]  A. Becke,et al.  Density-functional exchange-energy approximation with correct asymptotic behavior. , 1988, Physical review. A, General physics.

[66]  G. George,et al.  A 13-element Ge detector for fluorescence EXAFS , 1988 .

[67]  Parr,et al.  Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density. , 1988, Physical review. B, Condensed matter.

[68]  D. Evans,et al.  Water-soluble hexadentate Schiff-base ligands as sequestrating agents for iron(III) and gallium(III) , 1988 .

[69]  J. Perdew,et al.  Density-functional approximation for the correlation energy of the inhomogeneous electron gas. , 1986, Physical review. B, Condensed matter.

[70]  R. A. Scott.  [23] Measurement of metal-ligand distances by EXAFS , 1985 .

[71]  K. Hodgson,et al.  Polarized x-ray absorption spectra of oriented plastocyanin single crystals. Investigation of methionine-copper coordination , 1982 .

[72]  K. Hodgson,et al.  A systematic x-ray absorption study of molybdenum complexes. The accuracy of structural information from extended x-ray absorption fine structure , 1978 .

[73]  J. Enemark,et al.  Principles of structure, bonding, and reactivity for metal nitrosyl complexes , 1974 .

[74]  J. Loliger,et al.  Paramagnetic moment measurements by nmr. A micro technique , 1972 .

[75]  D. F. Evans.  400. The determination of the paramagnetic susceptibility of substances in solution by nuclear magnetic resonance , 1959 .