EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling

[1]  Lishen Ren,et al.  EYA2 upregulates miR-93 to promote tumorigenesis of breast cancer by targeting and inhibiting the STING signaling pathway. , 2021, Carcinogenesis.

[2]  Wei Li,et al.  LINC00669 insulates the JAK/STAT suppressor SOCS1 to promote nasopharyngeal cancer cell proliferation and invasion , 2020, Journal of experimental & clinical cancer research : CR.

[3]  S. Ramanathan,et al.  Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma , 2020, BMC Cancer.

[4]  A. Gonzalez-Perez,et al.  A compendium of mutational cancer driver genes , 2020, Nature Reviews Cancer.

[5]  Lili Yan,et al.  Correlation of PD-L1 and SOCS3 Co-expression with the Prognosis of Hepatocellular Carcinoma Patients , 2020, Journal of Cancer.

[6]  A. Goldberg,et al.  cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases , 2020, Proceedings of the National Academy of Sciences.

[7]  S. Rebouissou,et al.  Advances in molecular classification and precision oncology in hepatocellular carcinoma. , 2020, Journal of hepatology.

[8]  Xiaofan Ding,et al.  Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas. , 2019, Gastroenterology.

[9]  Jing-Wei Zhu,et al.  Expression and prognostic value of HER-2/neu, STAT3 and SOCS3 in hepatocellular carcinoma. , 2019, Clinics and research in hepatology and gastroenterology.

[10]  Hui Zhou,et al.  C1QTNF1-AS1 regulates the occurrence and development of hepatocellular carcinoma by regulating miR-221-3p/SOCS3 , 2019, Hepatology International.

[11]  Weihua Ren,et al.  MicroRNA-196a/-196b regulate the progression of hepatocellular carcinoma through modulating the JAK/STAT pathway via targeting SOCS2 , 2019, Cell Death and Disease.

[12]  E. Katsuyama,et al.  Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells , 2019, Scientific Reports.

[13]  Kongming Wu,et al.  EYA2 Correlates With Clinico-Pathological Features of Breast Cancer, Promotes Tumor Proliferation, and Predicts Poor Survival , 2019, Front. Oncol..

[14]  Jianhua Lin,et al.  miR-219a-5p represses migration and invasion of osteosarcoma cells via targeting EYA2 , 2018, Artificial cells, nanomedicine, and biotechnology.

[15]  A. Iavarone,et al.  A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas , 2018, Nature Communications.

[16]  A. Medvedev,et al.  [Ubiquitin-independent protein degradation in proteasomes]. , 2018, Biomeditsinskaia khimiia.

[17]  Zhaoming Li,et al.  EYA2 promotes lung cancer cell proliferation by downregulating the expression of PTEN , 2017, Oncotarget.

[18]  Ah Ram Lee,et al.  Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5′-UTR of TRIM22 , 2017, Gut.

[19]  H. Bian,et al.  A three-caller pipeline for variant analysis of cancer whole-exome sequencing data , 2017, Molecular medicine reports.

[20]  L. Roberts,et al.  Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances , 2016, F1000Research.

[21]  Chun‐Hsiang Wang,et al.  Current trends and recent advances in diagnosis, therapy, and prevention of hepatocellular carcinoma. , 2015, Asian Pacific journal of cancer prevention : APJCP.

[22]  X. Guan,et al.  The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update , 2014, Protein & Cell.

[23]  A. Maitra,et al.  Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth , 2014, Oncotarget.

[24]  N. Nicola,et al.  Inhibition of IL-6 family cytokines by SOCS3. , 2014, Seminars in immunology.

[25]  Lin Li,et al.  Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma , 2013, Genome research.

[26]  Min Jae Lee,et al.  Tau degradation: The ubiquitin–proteasome system versus the autophagy-lysosome system , 2013, Progress in Neurobiology.

[27]  R. Hegde,et al.  The Eyes Absent proteins in development and disease , 2012, Cellular and Molecular Life Sciences.

[28]  Bin Tean Teh,et al.  Exome sequencing of liver fluke–associated cholangiocarcinoma , 2012, Nature Genetics.

[29]  J. Bromberg,et al.  Targeting the interleukin-6/Jak/stat pathway in human malignancies. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[30]  H. Ford,et al.  Eya2 Is Required to Mediate the Pro-Metastatic Functions of Six1 Via the Induction of TGF-β Signaling, Epithelial-Mesenchymal Transition, and Cancer Stem Cell Properties , 2011, Oncogene.

[31]  D. Jun,et al.  Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells. , 2011, Biochemical pharmacology.

[32]  J. Mallet,et al.  SOCS3-Mediated Blockade of JAK/STAT3 Signaling Pathway Reveals Its Major Contribution to Spinal Cord Neuroinflammation and Mechanical Allodynia after Peripheral Nerve Injury , 2010, The Journal of Neuroscience.

[33]  I. Rebay,et al.  Interactions with the Abelson tyrosine kinase reveal compartmentalization of eyes absent function between nucleus and cytoplasm. , 2009, Developmental cell.

[34]  R. Beyer,et al.  Regulation of liver regeneration and hepatocarcinogenesis by suppressor of cytokine signaling 3 , 2008, The Journal of experimental medicine.

[35]  I. Rebay,et al.  The eyes absent family of phosphotyrosine phosphatases: properties and roles in developmental regulation of transcription. , 2007, Annual review of biochemistry.

[36]  Terence P. Speed,et al.  The Comparative Roles of Suppressor of Cytokine Signaling-1 and -3 in the Inhibition and Desensitization of Cytokine Signaling* , 2006, Journal of Biological Chemistry.

[37]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[38]  G. Mardon,et al.  Dachshund and Eyes Absent Proteins Form a Complex and Function Synergistically to Induce Ectopic Eye Development in Drosophila , 1997, Cell.