In-vitro Reactivity and Antibacterial Activity of Agro-waste Derived Silicate and Phosphate Glasses

Two different categories of bioactive glasses prepared from biomass using SiO2 and P2O5 as glass formers are reported in this study. These glasses are prepared by melt-quench technique. The glasses are evaluated in-vitro for their bioactivity assessment with the help of simulated body fluid (SBF). The formation of hydroxyapatite (HAp) above the glass surface is taken as an indicator for the glasses to be bioactive. Hence, various experimental techniques like X-Ray diffraction, Scanning electron microscopy, Energy dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, and Microwave plasma atomic emission spectroscopy are employed to assess the formation of HAp layer above the glass surface. All these results confirmed the formation of HAp layer. Further, drug loading and antibacterial studies were carried out to investigate the application of glass samples as drug delivery vehicles and antibacterial agents, respectively. These investigations proved that the as-prepared glass samples have high drug loading efficiency and antibacterial activity.

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