QRS detection method based on fully convolutional networks for capacitive electrocardiogram

Abstract A capacitive electrocardiogram (cECG) signal is considered a promising alternative to a conventional contact electrocardiogram (ECG) signal because the cECG signal can serve the same purpose as the contact ECG signal but can be measured during daily life without causing a subject to feel uncomfortable. However, the cECG signal has a limitation in that detection of QRS complexes, which is a fundamental step to analyze heart condition, is not easy. That is because the cECG signal is sensitive to noise, especially motion noise. This paper proposes a method to detect QRS complexes in cECG signals degraded by motion noise. The proposed method is based on fully convolutional networks (FCNs) and mainly consists of three parts: the generation of ground-truth data, the FCN model, and postprocessing. A labeling process for generating the ground-truth data is proposed. Then, an FCN model that is suitable for cECG signals is proposed. The proposed FCN model uses filters of a large size to achieve a large receptive field, unlike the common FCN models used in image processing. The receptive field is sufficiently large to involve information about adjacent QRS complexes, such as the time interval between the QRS complexes and its variability. By considering the information, the proposed FCN model can reliably classify QRS complexes even in cECG signals degraded by motion noise. Additionally, postprocessing, which consists of an accumulation step and a non-maximum suppression step, is proposed to complement the proposed FCN model. In experiments with real data, the proposed method showed an average sensitivity of 96.94%, positive predictive value of 99.13%, and F1 score of 98.02%. These results demonstrate that the proposed method overcomes the limitation of a cECG signal and helps the cECG signal be widely utilized for medical or healthcare applications.

[1]  S. S. Mehta,et al.  SVM-based algorithm for recognition of QRS complexes in electrocardiogram , 2008 .

[2]  Lars S. Maier,et al.  First clinical evaluation of a novel capacitive ECG system in patients with acute myocardial infarction , 2011, Clinical Research in Cardiology.

[3]  Pablo Laguna,et al.  Drowsiness detection using heart rate variability , 2016, Medical & Biological Engineering & Computing.

[4]  P. Stein,et al.  Heart Rate Variability: Measurement and Clinical Utility , 2005, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[5]  Willis J. Tompkins,et al.  A Real-Time QRS Detection Algorithm , 1985, IEEE Transactions on Biomedical Engineering.

[6]  Peter Rossiter,et al.  Applying neural network analysis on heart rate variability data to assess driver fatigue , 2011, Expert Syst. Appl..

[7]  Arun Khosla,et al.  QRS detection using K-Nearest Neighbor algorithm (KNN) and evaluation on standard ECG databases , 2012, Journal of advanced research.

[8]  Stephan Heuer,et al.  Motion Artefacts in Capacitively Coupled ECG Electrodes , 2009 .

[9]  M. Sokolow,et al.  The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. , 1949, American heart journal.

[10]  Manuel Merino,et al.  Envelopment filter and K-means for the detection of QRS waveforms in electrocardiogram. , 2015, Medical engineering & physics.

[11]  M. Fullana,et al.  Self-implication and heart rate variability during simulated exposure to flight-related stimuli , 2004 .

[12]  Sang Woo Kim,et al.  Adaptive Noise Reduction Algorithm to Improve R Peak Detection in ECG Measured by Capacitive ECG Sensors , 2018, Sensors.

[13]  Steffen Leonhardt,et al.  The smart car seat: personalized monitoring of vital signs in automotive applications , 2011, Personal and Ubiquitous Computing.

[14]  Steffen Leonhardt,et al.  UnoViS: the MedIT public unobtrusive vital signs database , 2015, Health Information Science and Systems.

[15]  Masaaki Makikawa,et al.  ECG monitoring of a car driver using capacitively-coupled electrodes , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[16]  Steffen Leonhardt,et al.  ECG on the Road: Robust and Unobtrusive Estimation of Heart Rate , 2011, IEEE Transactions on Biomedical Engineering.

[17]  Nitish Srivastava,et al.  Dropout: a simple way to prevent neural networks from overfitting , 2014, J. Mach. Learn. Res..

[18]  Sule Yücelbas,et al.  Automatic sleep staging based on SVD, VMD, HHT and morphological features of single-lead ECG signal , 2018, Expert Syst. Appl..

[19]  Marko Sarlija,et al.  A convolutional neural network based approach to QRS detection , 2017, Proceedings of the 10th International Symposium on Image and Signal Processing and Analysis.

[20]  John G. Webster,et al.  Driven-right-leg circuit design , 1983, IEEE Transactions on Biomedical Engineering.

[21]  Tsuyoshi Kato,et al.  Capacitive Sensing of Electrocardiographic Potential Through Cloth From the Dorsal Surface of the Body in a Supine Position: A Preliminary Study , 2007, IEEE Transactions on Biomedical Engineering.

[22]  Stephan Heuer,et al.  Motion artefact correction for capacitive ECG measurement , 2009, 2009 IEEE Biomedical Circuits and Systems Conference.

[23]  S. Leonhardt,et al.  Non-contact ECG monitoring for automotive application , 2008, 2008 5th International Summer School and Symposium on Medical Devices and Biosensors.

[24]  M. Makikawa,et al.  ECG Measurement Using Capacitive Coupling Electrodes for Man-Machine Emotional Communication , 2007, 2007 IEEE/ICME International Conference on Complex Medical Engineering.

[25]  Steffen Leonhardt,et al.  Automatic electrode selection in unobtrusive capacitive ECG measurements , 2012, 2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS).

[26]  Sarabjeet Singh Mehta,et al.  Development of SVM based classification techniques for the delineation of wave components in 12-lead electrocardiogram , 2008, Biomed. Signal Process. Control..

[27]  John G. Webster,et al.  Medical Instrumentation: Application and Design , 1997 .

[28]  David Menotti,et al.  ECG arrhythmia classification based on optimum-path forest , 2013, Expert Syst. Appl..

[29]  Pornchai Phukpattaranont,et al.  QRS detection algorithm based on the quadratic filter , 2015, Expert Syst. Appl..

[30]  S. Poornachandra,et al.  Wavelet-based denoising using subband dependent threshold for ECG signals , 2008, Digit. Signal Process..

[31]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[32]  Sang-Woo Kim,et al.  Recognition of Slab Identification Numbers using a Fully Convolutional Network , 2018 .

[33]  Rik Vullings,et al.  Motion Artifacts in Capacitive ECG Measurements: Reducing the Combined Effect of DC Voltages and Capacitance Changes Using an Injection Signal , 2015, IEEE Transactions on Biomedical Engineering.

[34]  Geoffrey E. Hinton,et al.  Rectified Linear Units Improve Restricted Boltzmann Machines , 2010, ICML.

[35]  P. Schauerte,et al.  The Reliability and Accuracy of a Noncontact Electrocardiograph System for Screening Purposes , 2012, Anesthesia and analgesia.

[36]  G.B. Moody,et al.  The impact of the MIT-BIH Arrhythmia Database , 2001, IEEE Engineering in Medicine and Biology Magazine.

[37]  Pawe Pawiak,et al.  Novel methodology of cardiac health recognition based on ECG signals and evolutionary-neural system , 2018 .

[38]  Sandeep Raj,et al.  Sparse representation of ECG signals for automated recognition of cardiac arrhythmias , 2018, Expert Syst. Appl..

[39]  Seung Hun Kim,et al.  Reduction of Motion Artifacts and Improvement of R Peak Detecting Accuracy Using Adjacent Non-Intrusive ECG Sensors , 2016, Sensors.

[40]  Yong Gyu Lim,et al.  ECG measurement on a chair without conductive contact , 2006, IEEE Transactions on Biomedical Engineering.

[41]  Américo Oliveira,et al.  Retinal vessel segmentation based on Fully Convolutional Neural Networks , 2018, Expert Syst. Appl..

[42]  S. S. Mehta,et al.  K-means algorithm for the detection and delineation of QRS-complexes in Electrocardiogram , 2010 .