A survey of nephrologists' views on preemptive transplantation.

BACKGROUND AND OBJECTIVES Despite emerging evidence that preemptive transplantation is the best treatment modality for patients reaching end-stage renal disease (ESRD), it is underutilized. Nephrologists' views on preemptive transplantation are explored herein. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS A web-based survey elicited barriers to preemptive transplantation as perceived by nephrologists as well as demographic and practice variables associated with a favorable attitude toward preemptive transplantation. RESULTS Four hundred seventy-six of 5,901 eligible nephrologists responded (8% participation rate). Seventy-one percent of respondents agreed that preemptive transplantation is the best treatment modality for eligible chronic kidney disease (CKD) patients reaching ESRD, 69% reported that late referrals did not allow enough time for patients to be evaluated for preemptive transplantation, and 50% stated that there was too much delay between a patient's referral and the time the patient was seen at the transplant center. Nephrologists agreed to a lesser extent that they should be held accountable for CKD patients' education (26%) and preemptive transplant referrals (23%). The most important patient factors considered when deciding not to discuss preemptive transplant were poor health status (70%), lack of compliance (69%), other medical problems (51%), being too old (40%), lack of prescription coverage (37%), and lack of health insurance to cover the costs of the procedure (36%). CONCLUSIONS Surveyed nephrologists consider preemptive transplantation as the optimal treatment modality for eligible patients. Late referral, patient health and insurance status, and delayed transplant center evaluation are perceived as major barriers to preemptive transplantation.

[1]  R. Howard,et al.  Increasing Live Donor Kidney Transplantation: A Randomized Controlled Trial of a Home‐Based Educational Intervention , 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[2]  N. Powe,et al.  Identification and referral of patients with progressive CKD: a national study. , 2006, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[3]  A. Howard Long-term posttransplantation care: the expanding role of community nephrologists. , 2006, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[4]  A. Waterman,et al.  Living Donation Decision Making: Recipients' Concerns and Educational Needs , 2006, Progress in transplantation.

[5]  Y. Becker,et al.  Preemptive transplantation for patients with diabetes-related kidney disease. , 2006, Archives of internal medicine.

[6]  M. Joffe,et al.  Rates of completion of the medical evaluation for renal transplantation. , 2005, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[7]  F. Weng,et al.  A comparison of persons who present for preemptive and nonpreemptive kidney transplantation. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[8]  A. Cass,et al.  Late referral to a nephrologist reduces access to renal transplantation. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[9]  M. Weir,et al.  Preemptive Renal Transplantation: Why Not? , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[10]  Stephen Sutton,et al.  Using the Internet to conduct surveys of health professionals: a valid alternative? , 2003, Family practice.

[11]  C. Mullins,et al.  Exploring Donors' and Recipients' Attitudes about Living Donor Kidney Transplantation , 2003 .

[12]  A. Waterman,et al.  One organ donation, three perspectives: experiences of donors, recipients, and third parties with living kidney donation. , 2003 .

[13]  I. Sirois,et al.  Soluble Fas: a novel predictor of atherosclerosis in dialysis patients. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[14]  C. Mullins,et al.  Patients' attitudes about living donor transplantation and living donor nephrectomy. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[15]  H. Meier‐Kriesche,et al.  Waiting time on dialysis as the strongest modifiable risk factor for renal transplant outcomes: A Paired Donor Kidney Analysis1 , 2002, Transplantation.

[16]  Nancy Fink,et al.  The Timing of Specialist Evaluation in Chronic Kidney Disease and Mortality , 2002, Annals of Internal Medicine.

[17]  P. Roderick,et al.  Late referral for end-stage renal disease: a region-wide survey in the south west of England. , 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[18]  J. Avorn,et al.  Delayed nephrologist referral and inadequate vascular access in patients with advanced chronic kidney failure. , 2002, Journal of clinical epidemiology.

[19]  B. Kasiske,et al.  Preemptive kidney transplantation: the advantage and the advantaged. , 2002, Journal of the American Society of Nephrology : JASN.

[20]  Hyung L. Kim,et al.  Practice trends in the management of prostate disease by family practice physicians and general internists: an internet-based survey. , 2002, Urology.

[21]  Z. Massy,et al.  Longer duration of predialysis nephrological care is associated with improved long-term survival of dialysis patients. , 2001, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[22]  E. Gordon Patients' decisions for treatment of end-stage renal disease and their implications for access to transplantation. , 2001, Social science & medicine.

[23]  D. Dunn,et al.  2,500 Living Donor Kidney Transplants: A Single-Center Experience , 2001, Annals of surgery.

[24]  T. Koyanagi,et al.  Pre‐emptive renal transplantation in children , 2001, International journal of urology : official journal of the Japanese Urological Association.

[25]  M. Joffe,et al.  Effect of the use or nonuse of long-term dialysis on the subsequent survival of renal transplants from living donors. , 2001, The New England journal of medicine.

[26]  R. Clayman,et al.  Use of new technology in endourology and laparoscopy by american urologists: internet and postal survey. , 2000, Urology.

[27]  A. Levin Consequences of late referral on patient outcomes. , 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[28]  F. Port,et al.  Effect of waiting time on renal transplant outcome. , 2000, Kidney international.

[29]  A. Matas,et al.  PRE-EMPTIVE TRANSPLANTS FOR PATIENTS WITH RENAL FAILURE: An Argument Against Waiting Until Dialysis , 2000, Transplantation.

[30]  C. Hollowell,et al.  Internet and postal survey of endourologic practice patterns among American urologists. , 2000, The Journal of urology.

[31]  B. Chavers,et al.  Pretransplant dialysis status and outcome of renal transplantation in North American children: a NAPRTCS Study. North American Pediatric Renal Transplant Cooperative Study. , 2000, Transplantation.

[32]  E. Gordon,et al.  Patient-nephrologist discussions about kidney transplantation as a treatment option. , 2000, Advances in renal replacement therapy.

[33]  D. Dillman Mail and internet surveys , 1999 .

[34]  Bayley Ew,et al.  Perceptions of kidney transplant by persons with end stage renal disease. , 1999 .

[35]  C. Short,et al.  Pre-emptive kidney transplantation: the attractive alternative. , 1998, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[36]  G. Thiel Living kidney donor transplantation – new dimensions , 1998, Transplant international : official journal of the European Society for Organ Transplantation.

[37]  P. Cochat,et al.  Outcome of preemptive renal transplantation and pretransplantation dialysis in children , 1997, Pediatric Nephrology.

[38]  P. Kuo,et al.  Increased living donor volunteer rates with a formal recipient family education program. , 1997, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[39]  C. Gray,et al.  Preemptive cadaveric renal transplantation--clinical outcome. , 1996, Transplantation.

[40]  C. V. van Buren,et al.  Preemptive transplantation--an analysis of benefits and hazards in 85 cases. , 1991, Transplantation.

[41]  David B Matchar,et al.  Relationship between nephrologist care and progression of chronic kidney disease. , 2007, North Carolina medical journal.

[42]  G. Eknoyan,et al.  Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. , 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[43]  D. Stablein,et al.  North American Pediatric Renal Transplant Cooperative Study , 2003 .

[44]  M. Joffe,et al.  Dialysis prior to living donor kidney transplantation and rates of acute rejection. , 2003, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[45]  R V Patel,et al.  Practice patterns in the treatment of female urinary incontinence: a postal and internet survey. , 2001, Urology.

[46]  L. Agodoa,et al.  United States Renal Data System (USRDS). , 2000, Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia.

[47]  R. Schindler,et al.  Hypertension and allograft nephropathy--cause, consequence, or both? , 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.