Abstract Grid-To-Rod Fretting (GTRF) is one of the main causes of leaking fuel in a Pressurized Water Reactor (PWR). GTRF is caused by grid-to-rod gap, secondary flow, and axial/lateral turbulence caused pressure fluctuations within the fuel assembly, which produces rod vibration and wear. The cross flow and vortex shedding phenomenon produce low frequency vibration forces on fuel rods. In some plants, leaking fuel has been detected at the fuel inlet region of fuel assembly designs that do not have Protective Grid (P-grid) which, in addition to providing debris protection, also provides lateral stability against vibration. In order to understand the root cause of the fuel leaks, a thorough investigation of the flow field at the fuel inlet region is required. Leaking fuel has also been detected in the fuel inlet region in transition cores. In the transitional core arrangement, there are different fuel assembly designs next to each other. Due to the structure difference, there will be cross flow between fuel assemblies, which may be the initiating factor for fuel leaks. A method based on Computational Fluid Dynamics (CFD) has been developed in Westinghouse to predict the GTRF in the fuel inlet region. The fuel inlet region consists of the lower core plate, the bottom nozzle, the fuel rods, the thimble rods, the P-grid, and the bottom grid. This study employed CFD to investigate the unsteady forces on the fuel rods under typical reactor in-core conditions. Two fuel assembly (FA) inlet regions with and without the P-grid were simulated. The time history of the unsteady force components on fuel rods was recorded. Fast Fourier Transform (FFT) analyses were carried out for the force history. Compared to the data from operating plants, the new method predicted synchronized excitation forces on the rods that leaked in real operation. The CFD results also demonstrated the advantage of using the P-grid. GTRF at the fuel inlet region can be significantly reduced when the P-grid is used in Westinghouse fuel assembly designs.