Antibodies to Deoxyribonucleic Acid Irradiated with Ultraviolet Light: Detection by Precipitins and Immunofluorescence

Two rabbits were immunized with a complex consisting of ultravioietirradiated DNA and methylated bovine serum albumin. Serum antibodies reacted only with irradiated DNA, and the serological reaction was shown by immuneprecipitation and immunofluorescence.