论文信息 - An Integrated Approach to the Exposome

An Integrated Approach to the Exposome

The editorial by Lioy and Rappaport (2011) provides a timely addition to the discussion about the exposome and exposure science. We are encouraged by the recognition of the importance of combining measurements of personal exposure with measurements of biological markers of exposure. However, rather than focusing on two approaches (i.e., top-down vs. bottom-up), we advocate a fully integrated approach to measurement of the exposome.

Martie van Tongeren | John W. Cherrie | M. van Tongeren | J. Cherrie | M. V. van Tongeren

[1] N. Bayley. Bayley Scales of Infant Development , 1999 .

[2] Stephen M Rappaport,et al. Environment and Disease Risks , 2010, Science.

[3] C. Wild. Complementing the Genome with an “Exposome”: The Outstanding Challenge of Environmental Exposure Measurement in Molecular Epidemiology , 2005, Cancer Epidemiology Biomarkers & Prevention.

[4] Paolo Vineis,et al. The impact of new research technologies on our understanding of environmental causes of disease: the concept of clinical vulnerability , 2009, Environmental health : a global access science source.

[5] M. Hernán,et al. Causal knowledge as a prerequisite for confounding evaluation: an application to birth defects epidemiology. , 2002, American journal of epidemiology.

[6] R. Hornung,et al. Prenatal Bisphenol A Exposure and Early Childhood Behavior , 2009, Environmental health perspectives.

[7] Brian J. Bennett,et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease , 2011, Nature.

[8] D. Rice,et al. Does Rapid Metabolism Ensure Negligible Risk from Bisphenol A? , 2009, Environmental health perspectives.

[9] A Wolman,et al. The environment and disease. , 1976, Bulletin of the Pan American Health Organization.

[10] B. Brooks,et al. Behavior Rating Inventory of Executive Function – Preschool Version (BRIEF-P): Test Review and Clinical Guidelines for Use , 2010 .