Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients.
暂无分享,去创建一个
D. Sargent | S. Thibodeau | R. Goldberg | N. Foster | J. Laurie | F. Sinicrope | T. Witzig | A. French | K. Halling | R. Rego | Betsy La Plant
[1] D. Sargent,et al. Prognostic value of proliferation, apoptosis, defective DNA mismatch repair, and p53 overexpression in patients with resected Dukes' B2 or C colon cancer: a North Central Cancer Treatment Group Study. , 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[2] R. Wolff,et al. Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. , 2005, Gastroenterology.
[3] S. Kakar,et al. Mucinous carcinoma of the colon: correlation of loss of mismatch repair enzymes with clinicopathologic features and survival , 2004, Modern Pathology.
[4] B. Iacopetta,et al. CpG island methylator phenotype is an independent predictor of survival benefit from 5-fluorouracil in stage III colorectal cancer. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[5] Daniel J Sargent,et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. , 2003, The New England journal of medicine.
[6] C. Compton,et al. Characterization of sporadic colon cancer by patterns of genomic instability. , 2003, Cancer research.
[7] W. Lingle,et al. Centrosome amplification and the development of cancer , 2002, Oncogene.
[8] M. Leppert,et al. Prognostic significance of p53 mutations in colon cancer at the population level , 2002, International journal of cancer.
[9] D. Sargent,et al. Investigation of the prognostic and predictive value of thymidylate synthase, p53, and Ki-67 in patients with locally advanced colon cancer. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[10] D. Sargent,et al. Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] J. Herman,et al. Low-level microsatellite instability in most colorectal carcinomas. , 2002, Cancer research.
[12] D. Schaid,et al. The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. , 2001, American journal of human genetics.
[13] L. Aaltonen,et al. Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. , 2000, Gastroenterology.
[14] M. Perucho,et al. Late onset and high incidence of colon cancer of the mutator phenotype with hypermethylated hMLH1 gene in women. , 2000, Gastroenterology.
[15] A. de la Chapelle,et al. Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers. , 2000, The American journal of pathology.
[16] Carolyn Compton,et al. American Joint Committee on Cancer prognostic factors consensus conference , 2000, Cancer.
[17] S. Bull,et al. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer. , 2000, The New England journal of medicine.
[18] B. Iacopetta,et al. p53 Gene Mutation, Microsatellite Instability and Adjuvant Chemotherapy: Impact on Survival of 388 Patients with Dukes’ C Colon Carcinoma , 2000, Oncology.
[19] K. Endo,et al. Computerized nuclear morphometry is a useful technique for evaluating the high metastatic potential of colorectal adenocarcinoma , 1999, Cancer.
[20] L. Aaltonen,et al. Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[21] D. Schaid,et al. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. , 1999, Journal of the National Cancer Institute.
[22] F. Sinicrope,et al. Apoptotic and mitotic indices predict survival rates in lymph node-negative colon carcinomas. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[23] C. Boland,et al. Mismatch repair proficiency and in vitro response to 5-fluorouracil. , 1999, Gastroenterology.
[24] S Srivastava,et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. , 1998, Cancer research.
[25] S N Thibodeau,et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. , 1998, Cancer research.
[26] D. Schaid,et al. Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. , 1998, Cancer research.
[27] Bert Vogelstein,et al. Mutations of mitotic checkpoint genes in human cancers , 1998, Nature.
[28] A. Børresen-Dale,et al. Different genetic pathways to proximal and distal colorectal cancer influenced by sex‐related factors , 1997, International journal of cancer.
[29] K. Kinzler,et al. Genetic instability in colorectal cancers , 1997, Nature.
[30] K. Kinzler,et al. Lessons from Hereditary Colorectal Cancer , 1996, Cell.
[31] L. Aaltonen,et al. Better survival rates in patients with MLH1-associated hereditary colorectal cancer. , 1996, Gastroenterology.
[32] A. Rustgi,et al. DNA mismatch repair and cancer. , 1995, Gastroenterology.
[33] P. Grambsch,et al. Proportional hazards tests and diagnostics based on weighted residuals , 1994 .
[34] B. Vogelstein,et al. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. , 1994, The American journal of pathology.
[35] L. Aaltonen,et al. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. , 1993, Cancer research.
[36] Darryl Shibata,et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis , 1993, Nature.
[37] S N Thibodeau,et al. Microsatellite instability in cancer of the proximal colon. , 1993, Science.
[38] H. Wieand,et al. DNA ploidy and cell kinetic measurements as predictors of recurrence and survival in stages B2 and C colorectal adenocarcinoma , 1991, Cancer.
[39] J. Hardcastle,et al. The influence of tumour cell DNA content on survival in colorectal cancer: a detailed analysis. , 1990, British Journal of Cancer.
[40] S. Cha,et al. Colorectal cancer. Dukes' stage, tumor site, preoperative plasma CEA level, and patient prognosis related to tumor DNA ploidy pattern. , 1987, Archives of surgery.
[41] J. Arends,et al. Retrospective analysis of the prognostic significance of DNA content and proliferative activity in large bowel carcinoma. , 1987, Cancer research.
[42] J. Chmiel,et al. Prognostic implications of proliferative activity and DNA aneuploidy in colonic adenocarcinomas. , 1987, Laboratory investigation; a journal of technical methods and pathology.
[43] I W Taylor,et al. Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. , 1983, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[44] F. A. Coller,et al. THE PROGNOSTIC SIGNIFICANCE OF DIRECT EXTENSION OF CARCINOMA OF THE COLON AND RECTUM , 1954, Annals of surgery.
[45] A. Jemal,et al. Cancer Statistics, 2004 , 2004, CA: a cancer journal for clinicians.
[46] W. Bodmer,et al. Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait. , 2002, Cancer research.
[47] R. Gafà,et al. Prognostic significance of DNA ploidy in patients with stage II and stage III colon carcinoma , 1998, Cancer.
[48] D. Cox. Regression Models and Life-Tables , 1972 .