Blood Mercury Reporting in NHANES: Identifying Asian, Pacific Islander, Native American, and Multiracial Groups

Introduction Asians, Pacific Islanders, and Native Americans are a potentially high-risk group for dietary exposure to methylmercury through fish consumption. However, blood mercury levels in this group have not been identified in recent reports of the National Health and Nutrition Examination Survey (NHANES) for the years 1999–2002. Methods We used NHANES data from 1999–2002 to obtain population estimates of blood mercury levels among women of childbearing age classified as belonging to the “other” racial/ethnic group (Asian, Pacific Islander, Native American, and multiracial; n = 140). Blood mercury levels in this group were compared with those among all other women participants, classified as Mexican American, non-Hispanic black, non-Hispanic white, and “other” Hispanic. Results An estimated 16.59 ± 4.0% (mean ± SE) of adult female participants who self-identified as Asian, Pacific Islander, Native American, or multiracial (n = 140) had blood mercury levels ≥5.8 μg/L, and 27.26 ± 4.22% had levels ≥3.5 μg/L. Among remaining survey participants (n = 3,497), 5.08 ± 0.90% had blood mercury levels ≥5.8 μg/L, and 10.86 ± 1.45% had levels ≥3.5 μg/L. Conclusions Study subjects in NHANES who self-identified as Asian, Pacific Islander, Native American, or multiracial had a higher prevalence of elevated blood mercury than all other racial/ethnic participants in the survey. Future studies should address reasons for the high mercury levels in this group and explore possible interventions for lowering risk of methylmercury exposure in this population.

[1]  M. McDowell,et al.  Urinary mercury concentrations associated with dental restorations in adult women aged 16–49 years: United States, 1999–2000 , 2005, Occupational and Environmental Medicine.

[2]  H. Anderson,et al.  Fish consumption, advisory awareness, and hair mercury levels among women of childbearing age. , 2005, Environmental research.

[3]  Kari Seppänen,et al.  Mercury, Fish Oils, and Risk of Acute Coronary Events and Cardiovascular Disease, Coronary Heart Disease, and All-Cause Mortality in Men in Eastern Finland , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[4]  K. Mahaffey Mercury exposure: medical and public health issues. , 2005, Transactions of the American Clinical and Climatological Association.

[5]  Andrew Gorman,et al.  Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in amazon populations in Brazil: a cross-sectional study , 2004, Environmental health : a global access science source.

[6]  D. Rice The US EPA reference dose for methylmercury: sources of uncertainty. , 2004, Environmental research.

[7]  K. Mahaffey,et al.  Blood organic mercury and dietary mercury intake: National Health and Nutrition Examination Survey, 1999 and 2000. , 2004, Environmental health perspectives.

[8]  A. Beuter,et al.  Effect of chronic exposure to methylmercury on eye movements in Cree subjects , 2004, International archives of occupational and environmental health.

[9]  Blood mercury levels in young children and childbearing-aged women--United States, 1999-2002. , 2004, MMWR. Morbidity and mortality weekly report.

[10]  A. Stern,et al.  An assessment of the cord blood:maternal blood methylmercury ratio: implications for risk assessment. , 2003, Environmental health perspectives.

[11]  E. Silbergeld,et al.  Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus. , 2003, Environmental health perspectives.

[12]  N. Polissar,et al.  Asian American and Pacific Islander seafood consumption — a community-based study in King County, Washington , 2003, Journal of Exposure Analysis and Environmental Epidemiology.

[13]  E. Silbergeld,et al.  Environmental Health: A Global Access Science Source , 2003 .

[14]  E. Sheiner,et al.  Effect of occupational exposures on male fertility: literature review. , 2003, Industrial health.

[15]  B. Hamilton,et al.  Revised birth and fertility rates for the United States, 2000 and 2001. , 2003, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[16]  D. Rice,et al.  Methods and Rationale for Derivation of a Reference Dose for Methylmercury by the U.S. EPA , 2003, Risk analysis : an official publication of the Society for Risk Analysis.

[17]  J. Hightower,et al.  Mercury levels in high-end consumers of fish. , 2002, Environmental health perspectives.

[18]  C. Haines,et al.  Infertility, blood mercury concentrations and dietary seafood consumption: a case-control study. , 2003, BJOG : an international journal of obstetrics and gynaecology.

[19]  Frans J Kok,et al.  Mercury, fish oils, and the risk of myocardial infarction. , 2002, The New England journal of medicine.

[20]  J. Nielsen,et al.  Mercury-induced autoimmunity in mice. , 2002, Environmental health perspectives.

[21]  J. C. Hansen,et al.  Neurobehavioral performance of Inuit children with increased prenatal exposure to methylmercury , 2002, International journal of circumpolar health.

[22]  J. Jacobson,et al.  Prenatal exposure of the northern Québec Inuit infants to environmental contaminants. , 2001, Environmental health perspectives.

[23]  S. Yim,et al.  Whole blood mercury concentrations in subfertile males in Hong Kong , 2001, The Australian & New Zealand journal of obstetrics & gynaecology.

[24]  T. Lakka,et al.  Fish Oil–Derived Fatty Acids, Docosahexaenoic Acid and Docosapentaenoic Acid, and the Risk of Acute Coronary Events: The Kuopio Ischaemic Heart Disease Risk Factor Study , 2000, Circulation.

[25]  Jesse McKinnon,et al.  The Asian and Pacific Islander Population in the United States: Population Characteristics, March 1999. Current Population Reports. , 2000 .

[26]  T. Lakka,et al.  Mercury accumulation and accelerated progression of carotid atherosclerosis: a population-based prospective 4-year follow-up study in men in eastern Finland. , 2000, Atherosclerosis.

[27]  P. Bjerregaard,et al.  Organochlorines and heavy metals in pregnant women from the Disko Bay area in Greenland. , 2000, The Science of the total environment.

[28]  J. Olsen,et al.  Long-term follow-up of cognitive outcome after breech presentation at birth. , 1999, Epidemiology.

[29]  T. Kitano,et al.  An analysis of subjective complaints in a population living in a methylmercury-polluted area. , 1999, Environmental research.

[30]  E Budtz-Jørgensen,et al.  Prenatal methylmercury exposure as a cardiovascular risk factor at seven years of age. , 1999, Epidemiology.

[31]  A. Maseri,et al.  Marked elevation of myocardial trace elements in idiopathic dilated cardiomyopathy compared with secondary cardiac dysfunction. , 1999, Journal of the American College of Cardiology.

[32]  U. Lindh,et al.  Metal-specific lymphocytes: biomarkers of sensitivity in man. , 1999, Neuro endocrinology letters.

[33]  V. Stejskal,et al.  The role of metals in autoimmunity and the link to neuroendocrinology. , 1999, Neuro endocrinology letters.

[34]  F. Larribe,et al.  Preliminary evidence of neurotoxicity associated with eating fish from the Upper St. Lawrence River Lakes. , 1998, Neurotoxicology.

[35]  M. Dickman,et al.  Mercury and organochlorine exposure from fish consumption in Hong Kong. , 1998, Chemosphere.

[36]  L. Goldman,et al.  Biological monitoring for mercury within a community with soil and fish contamination. , 1997, Environmental health perspectives.

[37]  F. Noël,et al.  Varying mercury exposure with varying food source in a James Bay Cree community. , 1996, Arctic medical research.

[38]  J. Bernier,et al.  Immunotoxicity of heavy metals in relation to Great Lakes. , 1995, Environmental health perspectives.

[39]  J. Salonen,et al.  Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. , 1995, Circulation.

[40]  P. Bigazzi Autoimmunity and Heavy Metals , 1994, Lupus.

[41]  J. Ruedy,et al.  Methyl mercury exposure in northern Quebec. II. Neurologic findings in children. , 1983, American journal of epidemiology.