Molecular imprinting: at the edge of the third millennium.

Molecularly imprinted polymers (MIPs) represent a new class of materials that have artificially created receptor structures (1-3). Since their discovery in 1972, MIPs have attracted considerable interest from scientists and engineers involved with the development of chromatographic adsorbents, membranes, sensors and enzyme and receptor mimics.

[1]  F. Arnold,et al.  A glucose-sensing polymer , 1997, Nature Biotechnology.

[2]  Michael J. Whitcombe,et al.  A NEW METHOD FOR THE INTRODUCTION OF RECOGNITION SITE FUNCTIONALITY INTO POLYMERS PREPARED BY MOLECULAR IMPRINTING : SYNTHESIS AND CHARACTERIZATION OF POLYMERIC RECEPTORS FOR CHOLESTEROL , 1995 .

[3]  K Mosbach,et al.  Imprinted polymer-based sensor system for herbicides using differential-pulse voltammetry on screen-printed electrodes. , 1999, Analytical chemistry.

[4]  K. Timmis,et al.  Bioprotection of microbial communities from toxic phenol mixtures by a genetically designed pseudomonad , 1997, Nature Biotechnology.

[5]  O. Niwa,et al.  Interdigitated array microelectrodes as electrochemical sensors , 1997 .

[6]  Barbara Wandelt,et al.  Fluorescent Functional Recognition Sites through Molecular Imprinting. A Polymer-Based Fluorescent Chemosensor for Aqueous cAMP. , 1998 .

[7]  Ian A. Nicholls,et al.  Receptor and transport properties of imprinted polymer membranes – a review , 1999 .

[8]  T. Kamiya.  Flame retardants : Halogen debate sizzles but has little impact , 1998 .

[9]  B. Sellergren,et al.  Analysis of nicotine and its oxidation products in nicotine chewing gum by a molecularly imprinted solid-phase extraction. , 1998, Analytical chemistry.

[10]  C. Crabb.  Biosensors enliven the science of detection , 1998 .

[11]  Frances H. Arnold,et al.  Metal-coordination interactions in the template-mediated synthesis of substrate-selective polymers recognition of bis(imidazole) substrates by copper(II) iminodiacetate containing polymers , 1992 .

[12]  K. Shea,et al.  Evaluation of Binding and Origins of Specificity of 9-Ethyladenine Imprinted Polymers , 1997 .

[13]  H. González-Navarro,et al.  Improving lipase activity in solvent-free media by interfacial activation-based molecular bioimprinting , 1997 .

[14]  K Mosbach,et al.  Mimics of the binding sites of opioid receptors obtained by molecular imprinting of enkephalin and morphine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[15]  Klaus Mosbach,et al.  Drug assay using antibody mimics made by molecular imprinting , 1993, Nature.

[16]  K. Uchiyama,et al.  Capillary electrochromatographic separation of amino acid enantiomers using on-column prepared molecularly imprinted polymer. , 1997, Journal of pharmaceutical and biomedical analysis.

[17]  I. Karube,et al.  Selective piezoelectric odor sensors using molecularly imprinted polymers , 1999 .

[18]  Ronald Rogers.  Membrane materials market to grow steadily , 1998 .

[19]  A. El'skaya,et al.  Fluorescence detection of β-estradiol using a molecularly imprinted polymer , 2000 .

[20]  Franz L. Dickert,et al.  Molecularly Imprinted Sensor Layers for the Detection of Polycyclic Aromatic Hydrocarbons in Water , 1999 .

[21]  I. Karube,et al.  Optical detection of chloramphenicol using molecularly imprinted polymers. , 1997, Analytical chemistry.

[22]  Cameron Alexander,et al.  Bacteria-Mediated Lithography of Polymer Surfaces , 1996 .

[23]  O. Wolfbeis,et al.  Application of non-specific fluorescent dyes for monitoring enantio-selective ligand binding to molecularly imprinted polymers , 1999 .

[24]  L. M. Toth,et al.  Enhancement of uranyl adsorption capacity and selectivity on silica sol-gel glasses via molecular imprinting , 1997 .

[25]  Sergey A. Piletsky,et al.  Selective recognition of atrazine by molecularly imprinted polymer membranes. Development of conductometric sensor for herbicides detection , 1999 .

[26]  O. Uy,et al.  Polymer-based lanthanide luminescent sensor for detection of the hydrolysis product of the nerve agent Soman in water. , 1999, Analytical chemistry.

[27]  R. L. D'aquinc.  Biocatalysis makes headway in chemical , 1999 .

[28]  Stellan Hjertén,et al.  Gels mimicking antibodies in their selective recognition of proteins , 1997 .

[29]  K. Shea,et al.  Discrimination between Enantiomers of Structurally Related Molecules: Separation of Benzodiazepines by Molecularly Imprinted Polymers , 2000 .

[30]  M. Muldoon,et al.  Molecularly imprinted solid phase extraction of atrazine from beef liver extracts. , 1997, Analytical chemistry.

[31]  O. Wolfbeis,et al.  A spreader-bar approach to molecular architecture: formation of stable artificial chemoreceptors. , 1999, Angewandte Chemie.

[32]  J. Haginaka,et al.  An Unexpected Molecular Imprinting Effect for a Polyaromatic Hydrocarbon, Anthracene, Using Uniform Size Ethylene Dimethacrylate Particles , 1999 .