A novel opposition-based classifier for mass diagnosis in mammography images

In this paper, a novel opposition-based classifier has been developed which classifies breast masses into benign and malignant categories. An MLP network with a novel learning rule, called Opposite Weighted Back Propagation (OWBP), has been utilized as the classifier. The objective is increasing the convergence rate of MLP learning rules as well as improving the mass diagnostic performance. The input ROI, which is a suspected part of mammogram, is segmented manually by expert radiologists and subjected to some preprocessing stages such as histogram equalization, translation and scaling. Then, a group of features which are appropriate descriptors of mass shape, margin and density have been extracted from the preprocessed ROIs. The proposed features include circularity, Zernike moments, contrast, average gray level, NRL derivatives and SP. The proposed classifier has been trained with both traditional BP and OWBP learning rules and the performance have been evaluated. The system which utilizes OWPB learning rule yields a significantly faster training time than BP algorithm while the Az of the resulting CADx system is 0.944.

[1]  L. Bruce,et al.  Classifying mammographic mass shapes using the wavelet transform modulus-maxima method , 1999, IEEE Transactions on Medical Imaging.

[2]  Rangaraj M. Rangayyan,et al.  A review of computer-aided diagnosis of breast cancer: Toward the detection of subtle signs , 2007, J. Frankl. Inst..

[3]  Heng-Da Cheng,et al.  Approaches for automated detection and classification of masses in mammograms , 2006, Pattern Recognit..

[4]  Hamid R. Tizhoosh,et al.  Opposition-Based Learning: A New Scheme for Machine Intelligence , 2005, International Conference on Computational Intelligence for Modelling, Control and Automation and International Conference on Intelligent Agents, Web Technologies and Internet Commerce (CIMCA-IAWTIC'06).

[5]  Mario Ventresca,et al.  Oppositional Concepts in Computational Intelligence , 2008, Oppositional Concepts in Computational Intelligence.

[6]  Mario Ventresca,et al.  Improving the Convergence of Backpropagation by Opposite Transfer Functions , 2006, The 2006 IEEE International Joint Conference on Neural Network Proceedings.

[7]  J. Mottershead,et al.  Mode-shape recognition and finite element model updating using the Zernike moment descriptor , 2009 .

[8]  Fakhri Karray,et al.  Soft Computing and Tools of Intelligent Systems Design: Theory and Applications , 2004 .

[9]  M. Y. Mashor,et al.  Classification of Breast Lesions Using Artificial Neural Network , 2007 .

[10]  Ian W. Ricketts,et al.  The Mammographic Image Analysis Society digital mammogram database , 1994 .

[11]  Asoke K. Nandi,et al.  Development of tolerant features for characterization of masses in mammograms , 2009, Comput. Biol. Medicine.

[12]  Nikhil R. Pal,et al.  A multi-stage neural network aided system for detection of microcalcifications in digitized mammograms , 2008, Neurocomputing.