A Computational Model of Motor Neuron Degeneration
暂无分享,去创建一个
[1] P. Pasinelli,et al. Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis. , 2014, Biochimica et biophysica acta.
[2] Mackenzie W. Mathis,et al. Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS , 2014, Neuron.
[3] Y. Kaneda,et al. Accumulation of cytosolic calcium induces necroptotic cell death in human neuroblastoma. , 2014, Cancer research.
[4] T. A. Ryan,et al. Activity-Driven Local ATP Synthesis Is Required for Synaptic Function , 2014, Cell.
[5] Peter Jonas,et al. Loose Coupling Between Ca2+ Channels and Release Sensors at a Plastic Hippocampal Synapse , 2014, Science.
[6] A. Chiò,et al. The metabolic signature of C9ORF72-related ALS: FDG PET comparison with nonmutated patients , 2014, European Journal of Nuclear Medicine and Molecular Imaging.
[7] N. Renier,et al. Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin , 2013, Neuron.
[8] P. Caroni,et al. Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival , 2013, Neuron.
[9] George S. B. Williams,et al. Mitochondrial calcium uptake , 2013, Proceedings of the National Academy of Sciences.
[10] George S. B. Williams,et al. NCLX: the mitochondrial sodium calcium exchanger. , 2013, Journal of molecular and cellular cardiology.
[11] Robert H. Brown,et al. Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability. , 2013, Journal of neurophysiology.
[12] Nick C Fox,et al. Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels , 2013, Neuron.
[13] J. Paul Bolam,et al. The energy cost of action potential propagation in dopamine neurons: clues to susceptibility in Parkinson's disease , 2013, Front. Comput. Neurosci..
[14] Kristen M. Naegle,et al. Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration , 2013, Cell.
[15] D. Attwell,et al. Synaptic Energy Use and Supply , 2012, Neuron.
[16] R. Rizzuto,et al. The mitochondrial Ca(2+) uniporter. , 2012, Cell calcium.
[17] David Attwell,et al. Oxidative Phosphorylation, Not Glycolysis, Powers Presynaptic and Postsynaptic Mechanisms Underlying Brain Information Processing , 2012, The Journal of Neuroscience.
[18] Janel O. Johnson,et al. Frequency of the C9orf72 hexanucleotide repeat expansion in patients with amyotrophic lateral sclerosis and frontotemporal dementia: a cross-sectional study , 2012, The Lancet Neurology.
[19] Christine Grienberger,et al. Imaging Calcium in Neurons , 2012, Neuron.
[20] Sherif M. Elbasiouny,et al. Contribution of intrinsic properties and synaptic inputs to motoneuron discharge patterns: a simulation study. , 2012, Journal of neurophysiology.
[21] Nagarajan Venkateswaran,et al. Energetics Based Spike Generation of a Single Neuron: Simulation Results and Analysis , 2012, Front. Neuroenerg..
[22] D. Friel,et al. Combined computational and experimental approaches to understanding the Ca(2+) regulatory network in neurons. , 2012, Advances in experimental medicine and biology.
[23] S. Ajroud‐Driss,et al. SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis. , 2011, Archives of neurology.
[24] E. Schon,et al. Mitochondria: The Next (Neurode)Generation , 2011, Neuron.
[25] A. Nose,et al. Differential Control of Presynaptic CaMKII Activation and Translocation to Active Zones , 2011, The Journal of Neuroscience.
[26] P. Nissen,et al. P-type ATPases. , 2011, Annual review of biophysics.
[27] Patrizia Sola,et al. Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS , 2011, Neuron.
[28] Erik Sahai,et al. Deficits in axonal transport precede ALS symptoms in vivo , 2010, Proceedings of the National Academy of Sciences.
[29] Simon B. Laughlin,et al. Action Potential Energy Efficiency Varies Among Neuron Types in Vertebrates and Invertebrates , 2010, PLoS Comput. Biol..
[30] C. Henderson,et al. Motor neuron diversity in development and disease. , 2010, Annual review of neuroscience.
[31] T. Sejnowski,et al. Metabolic cost as a unifying principle governing neuronal biophysics , 2010, Proceedings of the National Academy of Sciences.
[32] Takeo Kato,et al. Mutations of optineurin in amyotrophic lateral sclerosis , 2010, Nature.
[33] K. Mills,et al. Detecting fasciculations in amyotrophic lateral sclerosis: duration of observation required , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[34] L. Rowland. Ameliorating amyotrophic lateral sclerosis. , 2010, The New England journal of medicine.
[35] G. Perkins,et al. Mitochondrial fragmentation in neurodegeneration , 2008, Nature Reviews Neuroscience.
[36] S. Laughlin,et al. Energy limitation as a selective pressure on the evolution of sensory systems , 2008, Journal of Experimental Biology.
[37] Xun Hu,et al. TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis , 2008, Science.
[38] Dick F. Stegeman,et al. Firing pattern of fasciculations in ALS , 2008, Neurology.
[39] M. Iwata,et al. Mitochondrial Alterations in the Spinal Cord of Patients With Sporadic Amyotrophic Lateral Sclerosis , 2007, Journal of neuropathology and experimental neurology.
[40] P. Gardiner,et al. Frequency–current relationships of rat hindlimb α‐motoneurones , 2006 .
[41] P. Gardiner,et al. Frequency-current relationships of rat hindlimb alpha-motoneurones. , 2006, The Journal of physiology.
[42] Giorgio A Ascoli,et al. Developmental changes in spinal motoneuron dendrites in neonatal mice , 2005, The Journal of comparative neurology.
[43] M. Swash,et al. Cramps, muscle pain, and fasciculations , 2004, Neurology.
[44] Terrence J. Sejnowski,et al. Synthesis of models for excitable membranes, synaptic transmission and neuromodulation using a common kinetic formalism , 1994, Journal of Computational Neuroscience.
[45] S. Dimauro,et al. Mitochondrial respiratory-chain diseases. , 2003, The New England journal of medicine.
[46] Kelvin E Jones,et al. A modelling study of locomotion‐induced hyperpolarization of voltage threshold in cat lumbar motoneurones , 2002, The Journal of physiology.
[47] Paul Bach-y-Rita,et al. The cost of an action potential , 2000, Journal of Neuroscience Methods.
[48] Margaret A. Johnson,et al. Mitochondrial enzyme activity in amyotrophic lateral sclerosis: Implications for the role of mitochondria in neuronal cell death , 1999, Annals of neurology.
[49] D. Kernell,et al. Discharge properties of motoneurones: How are they matched to the properties and use of their muscle units? , 1999, Journal of Physiology-Paris.
[50] P. Pohl,et al. The size of the unstirred layer as a function of the solute diffusion coefficient. , 1998, Biophysical journal.
[51] M. Berridge. Neuronal Calcium Signaling , 1998, Neuron.
[52] J C Pearson,et al. Distribution of 5‐hydroxytryptamine‐immunoreactive boutons on α‐motoneurons in the lumbar spinal cord of adult cats , 1998, The Journal of comparative neurology.
[53] M. Swash,et al. Fasciculation potentials: A study of amyotrophic lateral sclerosis and other neurogenic disorders , 1998, Muscle & nerve.
[54] M. Swash,et al. Fasciculations: what do we know of their significance? , 1997, Journal of the Neurological Sciences.
[55] Nicholas T. Carnevale,et al. The NEURON Simulation Environment , 1997, Neural Computation.
[56] B. Locke,et al. The effects of temperature, pH, and magnesium on the diffusion coefficient of ATP in solutions of physiological ionic strength. , 1996, Biochimica et biophysica acta.
[57] D. Clapham,et al. Calcium signaling , 1995, Cell.
[58] R. Layzer. The origin of muscle fasciculations and cramps , 1994, Muscle & nerve.
[59] M D Binder,et al. Computer simulations of motoneuron firing rate modulation. , 1993, Journal of neurophysiology.
[60] E. Marder,et al. Activity-dependent regulation of conductances in model neurons. , 1993, Science.
[61] A. Hodgkin,et al. A quantitative description of membrane current and its application to conduction and excitation in nerve , 1990, Bulletin of mathematical biology.
[62] W. N. Ross,et al. Changes in intracellular calcium during neuron activity. , 1989, Annual review of physiology.
[63] R. Burke,et al. Membrane area and dendritic structure in type‐identified triceps surae alpha motoneurons , 1987, The Journal of comparative neurology.
[64] R. Broadwell,et al. The neuronal endoplasmic reticulum: Its cytochemistry and contribution to the endomembrane system. II. Axons and terminals , 1984, The Journal of comparative neurology.
[65] L. Kurland,et al. Fine Structural Study of Neurofibrillary Changes in a Family with Amyotrophic Lateral Sclerosis , 1984, Journal of neuropathology and experimental neurology.
[66] R. Broadwell,et al. The neuronal endoplasmic reticulum: its cytochemistry and contribution to the endomembrane system. I. Cell bodies and dendrites. , 1983, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[67] G Roth,et al. The origin of fasciculations , 1982, Annals of neurology.
[68] R. Burke. Motor unit types: functional specializations in motor control , 1980, Trends in Neurosciences.
[69] W. Crill,et al. Voltage‐sensitive outward currents in cat motoneurones. , 1980, The Journal of physiology.
[70] W. Brown. Functional compensation of human motor units in health and disease. , 1973, Journal of the neurological sciences.
[71] C. Terzuolo,et al. Membrane currents in spinal motoneurons associated with the action potential and synaptic activity. , 1962, Journal of neurophysiology.
[72] D. Denny-Brown,et al. FIBRILLATION AND FASCICULATION IN VOLUNTARY MUSCLE , 1938 .