Incidence and types of preventable adverse events in elderly patients: population based review of medical records

Abstract Objectives: To determine the incidence and types of preventable adverse events in elderly patients. Design: Review of random sample of medical records in two stage process by nurses and physicians to detect adverse events. Two study investigators then judged preventability. Setting: Hospitals in US states of Utah and Colorado, excluding psychiatric and Veterans Administration hospitals. Subjects: 15 000 hospitalised patients discharged in 1992. Main outcome measures: Incidence of preventable adverse events (number of preventable events per 100 discharges) in elderly patients (65 years old) and non-elderly patients (16-64 years). Results: When results were extrapolated to represent all discharges in 1992 in both states, non-elderly patients had 8901 adverse events (incidence 2.80% (SE 0.18%)) compared with 7419 (5.29% (0.37%)) among elderly patients (P=0.001). Non-elderly patients had 5038 preventable adverse events (incidence 1.58% (0.14%)) compared with 4134 (2.95% (0.28%)) in elderly patients (P=0.001). Elderly patients had a higher incidence of preventable events related to medical procedures (such as thoracentesis, cardiac catheterisation) (0.69% (0.14%) v 0.13% (0.04%)), preventable adverse drug events (0.63% (0.14%) v 0.17% (0.05%)), and preventable falls (0.10% (0.06%) v 0.01% (0.02%)). In multivariate analyses, adjusted for comorbid illnesses and case mix, age was not an independent predictor of preventable adverse events. Conclusion: Preventable adverse events were more common among elderly patients, probably because of the clinical complexity of their care rather than age based discrimination. Preventable adverse drug events, events related to medical procedures, and falls were especially common in elderly patients and should be targets for efforts to prevent errors.

[1]  N. Laird,et al.  Incidence of Adverse Drug Events and Potential Adverse Drug Events: Implications for Prevention , 1995 .

[2]  L. Kohn,et al.  To Err Is Human : Building a Safer Health System , 2007 .

[3]  D. Jahnigen,et al.  Iatrogenic Disease in Hospitalized Elderly Veterans , 1982, Journal of the American Geriatrics Society.

[4]  C. Wild Building a safer health system , 2001 .

[5]  T. Brennan,et al.  Incidence and types of adverse events and negligent care in Utah and Colorado. , 2000, Medical care.

[6]  A. Egberts,et al.  Adverse drug events in hospitalized patients A comparison of doctors, nurses and patients as sources of reports , 1999, European Journal of Clinical Pharmacology.

[7]  T. Brennan,et al.  The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. , 1991, The New England journal of medicine.

[8]  P T Davis Adverse drug events in hospitalized patients. , 1997, JAMA.

[9]  D. Classen,et al.  Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality. , 1997, JAMA.

[10]  J. McCulloch,et al.  CHAPTER 7 – Implications for Prevention , 1972 .

[11]  E. Marcantonio,et al.  How should clinical care of the aged differ? , 1997, The Lancet.

[12]  M. Sager,et al.  Adverse drug events in hospitalized elderly. , 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

[13]  P. Diggle Analysis of Longitudinal Data , 1995 .

[14]  D I Clemmer,et al.  Hospital falls: a persistent problem. , 1985, American journal of public health.

[15]  P M Gertman,et al.  Iatrogenic illness on a general medical service at a university hospital* , 1981, Quality and Safety in Health Care.

[16]  H. Cohen,et al.  Hospital-acquired complications in a randomized controlled clinical trial of a geriatric consultation team. , 1987, JAMA.

[17]  T. Brennan,et al.  INCIDENCE OF ADVERSE EVENTS AND NEGLIGENCE IN HOSPITALIZED PATIENTS , 2008 .