A color-corrected strategy for information multiplexed Fourier ptychographic imaging

Abstract Fourier ptychography (FP) is a novel computational imaging technique that provides both wide field of view (FoV) and high-resolution (HR) imaging capacity for biomedical imaging. Combined with information multiplexing technology, wavelength multiplexed (or color multiplexed) FP imaging can be implemented by lighting up R/G/B LED units simultaneously. Furthermore, a HR image can be recovered at each wavelength from the multiplexed dataset. This enhances the efficiency of data acquisition. However, since the same dataset of intensity measurement is used to recover the HR image at each wavelength, the mean value in each channel would converge to the same value. In this paper, a color correction strategy embedded in the multiplexing FP scheme is demonstrated, which is termed as color corrected wavelength multiplexed Fourier ptychography (CWMFP). Three images captured by turning on a LED array in R/G/B are required as priori knowledge to improve the accuracy of reconstruction in the recovery process. Using the reported technique, the redundancy requirement of information multiplexed FP is reduced. Moreover, the accuracy of reconstruction at each channel is improved with correct color reproduction of the specimen.

[1]  Brendan Ames,et al.  Solving ptychography with a convex relaxation , 2014, New journal of physics.

[2]  Siyuan Dong,et al.  Spectral multiplexing and coherent-state decomposition in Fourier ptychographic imaging. , 2014, Biomedical optics express.

[3]  Yibo Zhang,et al.  Color calibration and fusion of lens-free and mobile-phone microscopy images for high-resolution and accurate color reproduction , 2016, Scientific Reports.

[4]  J R Fienup,et al.  Phase retrieval algorithms: a comparison. , 1982, Applied optics.

[5]  David George Voelz,et al.  Computational Fourier Optics: A MATLAB Tutorial , 2011 .

[6]  Kannan Ramchandran,et al.  Multiplexed coded illumination for Fourier Ptychography with an LED array microscope. , 2014, Biomedical optics express.

[7]  Qian Chen,et al.  Efficient positional misalignment correction method for Fourier ptychographic microscopy. , 2016, Biomedical optics express.

[8]  R. Gerchberg.  A practical algorithm for the determination of phase from image and diffraction plane pictures , 1972 .

[9]  Helen Mullaly.  A Wide Field , 1978 .

[10]  Guoan Zheng,et al.  Sparsely sampled Fourier ptychography. , 2014, Optics express.

[11]  Andreas Menzel,et al.  Probe retrieval in ptychographic coherent diffractive imaging. , 2009, Ultramicroscopy.

[12]  Qian Chen,et al.  Adaptive step-size strategy for noise-robust Fourier ptychographic microscopy. , 2016, Optics express.

[13]  J. Rodenburg,et al.  Information multiplexing in ptychography. , 2014, Ultramicroscopy.

[14]  R. Horstmeyer,et al.  Wide-field, high-resolution Fourier ptychographic microscopy , 2013, Nature Photonics.

[15]  Aydogan Ozcan,et al.  Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy , 2012, Nature Methods.

[16]  Qian Chen,et al.  Sampling criteria for Fourier ptychographic microscopy in object space and frequency space. , 2016, Optics express.

[17]  Guoan Zheng,et al.  Breakthroughs in Photonics 2013: Fourier Ptychographic Imaging , 2014, IEEE Photonics Journal.

[18]  Laura Waller,et al.  Experimental robustness of Fourier Ptychography phase retrieval algorithms , 2015, Optics express.

[19]  Qian Chen,et al.  Adaptive denoising method for Fourier ptychographic microscopy , 2017 .

[20]  Guoan Zheng,et al.  Embedded pupil function recovery for Fourier ptychographic microscopy. , 2014, Optics express.

[21]  Guoan Zheng,et al.  Fourier Ptychographic Imaging: A Matlab Tutorial , 2016 .

[22]  Qionghai Dai,et al.  Motion-corrected Fourier ptychography. , 2016, Biomedical optics express.

[23]  J. Rodenburg.  Ptychography and Related Diffractive Imaging Methods , 2008 .

[24]  Guoan Zheng,et al.  Adaptive system correction for robust Fourier ptychographic imaging. , 2013, Optics express.

[25]  Qionghai Dai,et al.  Fourier ptychographic microscopy using a generalized Anscombe transform approximation of the mixed Poisson-Gaussian likelihood. , 2017, Optics express.

[26]  J. Rodenburg,et al.  An annealing algorithm to correct positioning errors in ptychography. , 2012, Ultramicroscopy.

[27]  Chao Zuo,et al.  Resolution-enhanced Fourier ptychographic microscopy based on high-numerical-aperture illuminations , 2017, Scientific Reports.