Metabolic stages, mitochondria and calcium in hypoxic/ischemic brain damage.
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[1] T. Wieloch,et al. Ultrastructural changes in the hippocampal CA1 region following transient cerebral ischemia: evidence against programmed cell death , 2005, Experimental Brain Research.
[2] B. Siesjö,et al. The influence of insulin-induced hypoglycemia on the calcium transients accompanying reversible forebrain ischemia in the rat , 1990, Experimental Brain Research.
[3] A. Halestrap,et al. Cyclosporin A binding in mitochondrial cyclophilin inhibits the permeability transition pore and protects hearts from ischaemia/reperfusion injury , 2004, Molecular and Cellular Biochemistry.
[4] B. Siesjö,et al. Influence of hyperglycemia and of hypercapnia on cellular calcium transients during reversible brain ischemia , 2004, Experimental Brain Research.
[5] B. Siesjö,et al. Perturbation of cellular energy state in complete ischemia: Relationship to dissipative ion fluxes , 2004, Experimental Brain Research.
[6] D. Nicholls,et al. Interactions between mitochondrial bioenergetics and cytoplasmic calcium in cultured cerebellar granule cells. , 2003, Cell calcium.
[7] S. Mehta. The glucose paradox of cerebral ischaemia. , 2003, Journal of postgraduate medicine.
[8] G. Fiskum,et al. Cyclosporin A-insensitive Permeability Transition in Brain Mitochondria , 2003, Journal of Biological Chemistry.
[9] P. Bernardi,et al. Mitochondria and reperfusion injury , 2003, Basic Research in Cardiology.
[10] P. Marsden,et al. Lactate: A Preferred Fuel for Human Brain Metabolism in Vivo , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[11] D. Nicholls,et al. The Relationship between Free and Total Calcium Concentrations in the Matrix of Liver and Brain Mitochondria* , 2003, Journal of Biological Chemistry.
[12] Eng H. Lo,et al. Neurological diseases: Mechanisms, challenges and opportunities in stroke , 2003, Nature Reviews Neuroscience.
[13] R. Clark,et al. To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways , 2003, Progress in Neurobiology.
[14] T. Weatherby,et al. Heterogeneity of the calcium‐induced permeability transition in isolated non‐synaptic brain mitochondria , 2002, Journal of neurochemistry.
[15] Gary Fiskum,et al. Regulation of hydrogen peroxide production by brain mitochondria by calcium and Bax , 2002, Journal of neurochemistry.
[16] T. Wieloch,et al. Mitochondrial permeability transition in acute neurodegeneration. , 2002, Biochimie.
[17] K. Moley,et al. Hyperglycemia‐induced apoptotic cell death in the mouse blastocyst is dependent on expression of p53 , 2001, Molecular reproduction and development.
[18] B. Siesjö,et al. Acidosis promotes the permeability transition in energized mitochondria: implications for reperfusion injury. , 2001, Journal of neurotrauma.
[19] K. Csiszȧr,et al. Does long-term glucose infusion reduce brain damage after transient cerebral ischemia? , 2001, Brain Research.
[20] J. Troppmair,et al. Independent control of cell survival by Raf-1 and Bcl-2 at the mitochondria , 2001, Oncogene.
[21] Fengqin Gao,et al. Novel Role for JNK as a Stress-activated Bcl2 Kinase* , 2001, The Journal of Biological Chemistry.
[22] P. Bernardi,et al. Opening of the Mitochondrial Permeability Transition Pore Causes Depletion of Mitochondrial and Cytosolic NAD+and Is a Causative Event in the Death of Myocytes in Postischemic Reperfusion of the Heart* , 2001, The Journal of Biological Chemistry.
[23] W. Schwindt,et al. Electron microscopic investigation of rat brain after brief cardiac arrest , 2001, Acta Neuropathologica.
[24] Y. Tsujimoto,et al. VDAC regulation by the Bcl-2 family of proteins , 2000, Cell Death and Differentiation.
[25] A. Buchan,et al. Apoptosis after experimental stroke: fact or fashion? , 2000, Journal of neurotrauma.
[26] G. Fiskum. Mitochondrial participation in ischemic and traumatic neural cell death. , 2000, Journal of neurotrauma.
[27] P. Stys,et al. Important role of reverse Na(+)-Ca(2+) exchange in spinal cord white matter injury at physiological temperature. , 2000, Journal of neurophysiology.
[28] P. Nicotera. Caspase Requirement for Neuronal Apoptosis and Neurodegeneration , 2000, IUBMB life.
[29] Guido Kroemer,et al. Mitochondrial control of cell death , 2000, Nature Medicine.
[30] B. Siesjö,et al. Characteristics of the Calcium‐Triggered Mitochondrial Permeability Transition in Nonsynaptic Brain Mitochondria , 2000, Journal of neurochemistry.
[31] S. Scheff,et al. Continuous Infusion of Cyclosporin A Postinjury Significantly Ameliorates Cortical Damage Following Traumatic Brain Injury , 2000, Experimental Neurology.
[32] Shuxin Li,et al. Mechanisms of Ionotropic Glutamate Receptor-Mediated Excitotoxicity in Isolated Spinal Cord White Matter , 2000, The Journal of Neuroscience.
[33] D. Andrews,et al. Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator , 2000, Oncogene.
[34] N. Sims,et al. Cyclosporin A‐Sensitive Changes in Mitochondrial Glutathione Are an Early Response to Intrastriatal NMDA or Forebrain Ischemia in Rats , 1999, Journal of neurochemistry.
[35] M. Tseng,et al. The Glucose Paradox in Cerebral Ischemia: New Insights , 1999, Annals of the New York Academy of Sciences.
[36] J. Hoek,et al. Functional Consequences of the Sustained or Transient Activation by Bax of the Mitochondrial Permeability Transition Pore* , 1999, The Journal of Biological Chemistry.
[37] M. Moskowitz,et al. Pathobiology of ischaemic stroke: an integrated view , 1999, Trends in Neurosciences.
[38] B. Siesjö,et al. Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia , 1999, Brain Research.
[39] T. Wieloch,et al. Blockade of the Mitochondrial Permeability Transition Pore Diminishes Infarct Size in the Rat after Transient Middle Cerebral Artery Occlusion , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[40] M. Blaustein,et al. Sodium/calcium exchange: its physiological implications. , 1999, Physiological reviews.
[41] S. Lipton,et al. Excitotoxins in Neuronal Apoptosis and Necrosis , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[42] G. Sutherland,et al. Electron Microscopic Evidence against Apoptosis as the Mechanism of Neuronal Death in Global Ischemia , 1999, The Journal of Neuroscience.
[43] U. Tuor,et al. Cerebral Ischemia Produces Laddered DNA Fragments Distinct from Cardiac Ischemia and Archetypal Apoptosis , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[44] P. Lipton,et al. Ischemic cell death in brain neurons. , 1999, Physiological reviews.
[45] P. Bernardi,et al. Mitochondrial transport of cations: channels, exchangers, and permeability transition. , 1999, Physiological reviews.
[46] R. Busto,et al. Cytochrome C Is Released from Mitochondria Into the Cytosol after Cerebral Anoxia or Ischemia , 1999, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[47] B. Siesjö,et al. Role and mechanisms of secondary mitochondrial failure. , 1999, Acta neurochirurgica. Supplement.
[48] T. Sugawara,et al. Mitochondrial release of cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. , 1999, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[49] L. Scorrano,et al. The mitochondrial permeability transition , 2022, BioFactors.
[50] S. Korsmeyer,et al. Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways , 1998, Nature Medicine.
[51] Ping-An Li,et al. Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat , 1998, Brain Research.
[52] G. Fiskum,et al. Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition , 1998, FEBS letters.
[53] M. Fujimura,et al. Cytosolic Redistribution of Cytochrome C after Transient Focal Cerebral Ischemia in Rats , 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[54] M. McKenna,et al. Lactate Transport by Cortical Synaptosomes from Adult Rat Brain: Characterization of Kinetics and Inhibitor Specificity , 1998, Developmental Neuroscience.
[55] T. Wieloch,et al. Cyclosporin A, But Not FK 506, Protects Mitochondria and Neurons against Hypoglycemic Damage and Implicates the Mitochondrial Permeability Transition in Cell Death , 1998, The Journal of Neuroscience.
[56] S. Kuroda,et al. Calcium metabolism of focal and penumbral tissues in rats subjected to transient middle cerebral artery occlusion , 1998, Experimental Brain Research.
[57] G. Kroemer,et al. The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins , 1998, The Journal of experimental medicine.
[58] J. Farber,et al. The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition* , 1998, The Journal of Biological Chemistry.
[59] B. Siesjö,et al. Calcium in ischemic cell death. , 1998, Stroke.
[60] N. Sims,et al. Ischemia in Rats , 2002 .
[61] I. Silver,et al. Oxygen and ion concentrations in normoxic and hypoxic brain cells. , 1998, Advances in experimental medicine and biology.
[62] K. Nagata. [Brain energy metabolism]. , 1997, Nihon rinsho. Japanese journal of clinical medicine.
[63] P. Stys,et al. Mechanisms of calcium and sodium fluxes in anoxic myelinated central nervous system axons , 1997, Neuroscience.
[64] B. Kristal,et al. Mitochondrial Permeability Transition in the Central Nervous System: Induction by Calcium Cycling‐Dependent and ‐Independent Pathways , 1997, Journal of neurochemistry.
[65] G Fiskum,et al. Neuroprotective effects of acetyl-L-carnitine after stroke in rats. , 1997, Annals of emergency medicine.
[66] S. Kuroda,et al. Release of mitochondrial aspartate aminotransferase (mAST) following transient focal cerebral ischemia suggests the opening of a mitochondrial permeability transition pore , 1997 .
[67] J. Turrens. Superoxide Production by the Mitochondrial Respiratory Chain , 1997, Bioscience reports.
[68] B. Siesjö,et al. Changes in ionic fluxes during cerebral ischaemia. , 1997, International review of neurobiology.
[69] B. Siesjö,et al. Extracellular potassium in a neocortical core area after transient focal ischemia. , 1997, Stroke.
[70] N. Sims,et al. Alterations in the glutathione content of mitochondria following short-term forebrain ischemia in rats , 1996, Neuroscience Letters.
[71] P. Magistretti,et al. Selective Distribution of Lactate Dehydrogenase Isoenzymes in Neurons and Astrocytes of Human Brain , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[72] B. Siesjö,et al. Calcium-related damage in ischemia. , 1996, Life sciences.
[73] Charles Tator,et al. Normal and abnormal calcium homeostasis in neurons: a basis for the pathophysiology of traumatic and ischemic central nervous system injury. , 1996, Neurosurgery.
[74] Paolo Bernardi,et al. The permeability transition pore as a mitochondrial calcium release channel: A critical appraisal , 1996, Journal of bioenergetics and biomembranes.
[75] B. Siesjö,et al. Acidosis-related damage. , 1996, Advances in neurology.
[76] I. Silver,et al. Calcium handling by hippocampal neurons under physiologic and pathologic conditions. , 1996, Advances in neurology.
[77] I. Silver,et al. The Effect of pH on Glycolysis and Phosphofructokinase Activity in Cultured Cells and Synaptosomes , 1995, Journal of neurochemistry.
[78] O. Lindvall,et al. Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat. , 1995, Acta physiologica Scandinavica.
[79] Á. Almeida,et al. Effect of Reperfusion Following Cerebral Ischaemia on the Activity of the Mitochondrial Respiratory Chain in the Gerbil Brain , 1995, Journal of neurochemistry.
[80] F. Tegtmeier,et al. Journal of Cerebral Blood Flow and Metabolism Ion Channel Involvement in Anoxic Depolarization Induced by Cardiac Arrest in Rat Brain , 2022 .
[81] Á. Almeida,et al. Changes of Respiratory Chain Activity in Mitochondrial and Synaptosomal Fractions Isolated from the Gerbil Brain After Graded Ischaemia , 1995, Journal of neurochemistry.
[82] A. Halestrap,et al. Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. , 1995, The Biochemical journal.
[83] E. Griffiths. Mitochondrial non-specific poresremain closed during cardiac ischaemia, , 1995 .
[84] N. Sims,et al. The Calcium Content of Mitochondria from Brain Subregions Following Short‐Term Forebrain Ischemia and Recirculation in the Rat , 1994, Journal of neurochemistry.
[85] P. Bernardi,et al. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane , 1994, Journal of bioenergetics and biomembranes.
[86] S. Heales,et al. Effects of 1‐Methyl‐4‐Phenylpyridinium on Isolated Rat Brain Mitochondria: Evidence for a Primary Involvement of Energy Depletion , 1994, Journal of neurochemistry.
[87] R. Rosenthal,et al. Postischemic inhibition of cerebral cortex pyruvate dehydrogenase. , 1994, Free radical biology & medicine.
[88] I. Silver,et al. Ions and energy in mammalian brain , 1994, Progress in Neurobiology.
[89] B. Siesjö,et al. The influence of pH on cellular calcium influx during ischemia , 1994, Brain Research.
[90] B. Siesjö,et al. Acidosis Induced by Hypercapnia Exaggerates Ischemic Brain Damage , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[91] R. Rosenthal,et al. Inhibition of postcardiac arrest brain protein oxidation by acetyl-L-carnitine. , 1993, Free radical biology & medicine.
[92] Charles Tator,et al. Secondary Ca2+ overload indicates early neuronal injury which precedes staining with viability indicators , 1993, Brain Research.
[93] B. Siesjö,et al. Coupling of cellular energy state and ion homeostasis during recovery following brain ischemia , 1993, Brain Research.
[94] N. Sims,et al. Journal of Cerebral Blood Flow and Metabolism Selective Reductions in the Activity of the Pyruvate Dehydrogenase Complex in Mitochondria Isolated from Brain Subregions following Forebrain Ischemia in Rats , 2022 .
[95] I. Silver,et al. Ion Homeostasis in Rat Brain in vivo: Intra- and Extracellular [Ca2+] and [H+] in the Hippocampus during Recovery from Short-Term, Transient Ischemia , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[96] B. Siesjö. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. , 1992, Journal of neurosurgery.
[97] R. Rosenthal,et al. Prevention of Postischemic Canine Neurological Injury Through Potentiation of Brain Energy Metabolism by Acetyl‐L‐Carnitine , 1992, Stroke.
[98] B. Siesjö,et al. Influence of Ischemia on Blood—Brain and Blood—CSF Calcium Transport , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[99] Y. Yonekawa,et al. Changes in major phospholipids of mitochondria during postischemic reperfusion in rat brain. , 1992, Journal of neurosurgery.
[100] Anders Ekholm,et al. Extra‐ and Intracellular pH in the Brain During Ischaemia, Related to Tissue Lactate Content in Normo‐and Hypercapnic rats , 1992, The European journal of neuroscience.
[101] W. Pulsinelli,et al. The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[102] S. Emoto,et al. Recovery of Postischemic Brain Metabolism and Function Following Treatment with a Free Radical Scavenger and Platelet‐Activating Factor Antagonists , 1991, Journal of neurochemistry.
[103] R. Myers,et al. Delayed decreases in specific brain mitochondrial electron transfer complex activities and cytochrome concentrations following anoxia/ischemia , 1990, Journal of the Neurological Sciences.
[104] B. Siesjö,et al. Phosphorylase a and Labile Metabolites During Anoxia: Correlation to Membrane Fluxes of K+ and Ca2+ , 1990, Journal of neurochemistry.
[105] N. Diemer,et al. N-methyl-D-aspartate and non-N-methyl-D-aspartate antagonists in global cerebral ischemia. , 1990, Stroke.
[106] T. Gunter,et al. Mechanisms by which mitochondria transport calcium. , 1990, The American journal of physiology.
[107] R. Myers,et al. Journal of Cerebral Blood Flow and Metabolism Delayed Onset of Neurologic Deterioration following Anoxia/ischemia Coincides with Appearance of Impaired Brain Mitochondrial Respiration and Decreased Cytochrome Oxidase Activity , 2022 .
[108] I A Silver,et al. Intracellular and extracellular changes of [Ca2+] in hypoxia and ischemia in rat brain in vivo , 1990, The Journal of general physiology.
[109] T. Wieloch,et al. Pyruvate Dehydrogenase Activity in the Rat Cerebral Cortex following Cerebral Ischemia , 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[110] I. Silver,et al. ATP and Brain Function , 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[111] N. Sims,et al. Altered Mitochondrial Respiration in Selectively Vulnerable Brain Subregions Following Transient Forebrain Ischemia in the Rat , 1987, Journal of neurochemistry.
[112] G. Mies,et al. Calcium in the mitochondria following brief ischemia of gerbil brain , 1987, Neuroscience Letters.
[113] B. Siesjö,et al. Ischemia in normo- and hyperglycemic rats: effects on brain water and electrolytes. , 1987, Stroke.
[114] B. Siesjö,et al. Journal of Cerebral Blood Flow and Metabolism Calcium Accumulation and Neuronal Damage in the Rat Hippocampus following Cerebral Ischemia Operative Procedures , 2022 .
[115] B. Siesjö,et al. Changes in Extra- and Intracellular pH in the Brain during and following Ischemia in Hyperglycemic and in Moderately Hypoglycemic Rats , 1986, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[116] A. Hansen,et al. Effect of anoxia on ion distribution in the brain. , 1985, Physiological reviews.
[117] L. Symon,et al. Extracellular pH, Potassium, and Calcium Activities in Progressive Ischaemia of Rat Cortex , 1984, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[118] A. Hansen,et al. Extracellular pH Changes during Spreading Depression and Cerebral Ischemia: Mechanisms of Brain pH Regulation , 1984, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[119] W. Moody,et al. Effects of intracellular H+ on the electrical properties of excitable cells. , 1984, Annual review of neuroscience.
[120] C. Nicholson. Dynamics of the brain cell microenvironment. , 1980, Neurosciences Research Program bulletin.
[121] B. Siesjö,et al. Rate of energy utilization in the cerebral cortex of rats. , 1975, Acta physiologica Scandinavica.
[122] B. Siesjö,et al. Influence of complete ischemia on glycolytic metabolites, citric acid cycle intermediates, and associated amino acids in the rat cerebral cortex. , 1974, Brain research.
[123] B. Siesjö,et al. Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia. , 1974, Brain research.
[124] R. Ratcheson,et al. Cerebral metabolic state following complete compression ischemia. , 1974, Brain research.
[125] O. H. Lowry,et al. CEREBRAL CARBOHYDRATE METABOLISM DURING ACUTE HYPOXIA AND RECOVERY 1 , 1972, Journal of neurochemistry.
[126] J J Pysh,et al. Variations in mitochondrial structure and content of neurons and neuroglia in rat brain: an electron microscopic study. , 1972, Brain research.
[127] O. H. Lowry,et al. The role of phosphofructokinase in metabolic regulation. , 1964, Advances in enzyme regulation.
[128] O. H. Lowry,et al. EFFECT OF ISCHEMIA ON KNOWN SUBSTRATES AND COFACTORS OF THE GLYCOLYTIC PATHWAY IN BRAIN. , 1964, The Journal of biological chemistry.
[129] R. A. Lovell,et al. THE α‐AMINOBUTYRIC ACID AND FACTOR I CONTENT OF BRAIN * , 1963 .
[130] R. A. Lovell,et al. THE GAMMA-AMINOBUTYRIC ACID AND FACTOR I CONTENT OF BRAIN. , 1963, Journal of neurochemistry.