The Soluble Interleukin‐6 Receptor a
暂无分享,去创建一个
[1] S. Rose-John,et al. Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells , 1994, The Journal of experimental medicine.
[2] S. Rose-John,et al. Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction. , 1994, Journal of immunology.
[3] P. Heinrich,et al. Soluble receptors for cytokines and growth factors: generation and biological function. , 1994, The Biochemical journal.
[4] P. Heinrich,et al. The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site. , 1994, Journal of immunology.
[5] G. Ciliberto,et al. Oncostatin M binds directly to gp130 and behaves as interleukin-6 antagonist on a cell line expressing gp130 but lacking functional oncostatin M receptors. , 1994, The Journal of biological chemistry.
[6] G. Ciliberto,et al. Interleukin‐6 deficient mice are protected from bone loss caused by estrogen depletion. , 1994, The EMBO journal.
[7] G. Ciliberto,et al. Generation of interleukin‐6 receptor antagonists by molecular‐modeling guided mutagenesis of residues important for gp130 activation. , 1994, The EMBO journal.
[8] S. Ziegler,et al. Proliferative responses and binding properties of hematopoietic cells transfected with low-affinity receptors for leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[9] S. Akira,et al. Cytokine signal transduction , 1994, Cell.
[10] P. Heinrich,et al. Development of a human interleukin-6 receptor antagonist. , 1994, The Journal of biological chemistry.
[11] D. Friend,et al. Multiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cells , 1994, Molecular and cellular biology.
[12] N. Udagawa,et al. Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[13] P. Heinrich,et al. Intracellular retention of interleukin-6 abrogates signaling. , 1993, The Journal of biological chemistry.
[14] P. Heinrich,et al. Differential shedding of the two subunits of the interleukin‐6 receptor , 1993, FEBS letters.
[15] G. Yancopoulos,et al. The alphas, betas, and kinases of cytokine receptor complexes , 1993, Cell.
[16] G. Yancopoulos,et al. Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. , 1993, Blood.
[17] P. Heinrich,et al. Recombinant soluble human interleukin-6 receptor. Expression in Escherichia coli, renaturation and purification. , 1993, European journal of biochemistry.
[18] P. Heinrich,et al. Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. , 1993, The Journal of biological chemistry.
[19] G. Yancopoulos,et al. LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. , 1993, Science.
[20] K. Yasukawa,et al. IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. , 1993, Science.
[21] D Eisenberg,et al. The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[22] M. Horowitz. Cytokines and estrogen in bone: anti-osteoporotic effects. , 1993, Science.
[23] P. Heinrich,et al. The soluble interleukin‐6 receptor is generated by shedding , 1993, European journal of immunology.
[24] P. Heinrich,et al. Protein kinase C activity is rate limiting for shedding of the interleukin-6 receptor. , 1992, Biochemical and biophysical research communications.
[25] L. D. Ward,et al. A major binding protein for leukemia inhibitory factor in normal mouse serum: identification as a soluble form of the cellular receptor. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[26] P. Heinrich,et al. Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins. , 1992, Journal of immunology.
[27] D. Fowlkes,et al. Identification of a receptor binding site in the carboxyl terminus of human interleukin-6. , 1992, The Journal of biological chemistry.
[28] K. Yasukawa,et al. Human soluble IL-6 receptor: its detection and enhanced release by HIV infection. , 1992, Journal of immunology.
[29] Comeau,et al. The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor. , 1992, Science.
[30] P. Heinrich,et al. Up‐regulation of the interleukin‐6‐signal transducing protein (gp130) by interleukin‐6 and dexamethasone in HepG2 cells , 1992, FEBS letters.
[31] T. Tedder. Cell-surface receptor shedding: a means of regulating function. , 1991, American journal of respiratory cell and molecular biology.
[32] T. Hirano,et al. Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells. , 1991, The Biochemical journal.
[33] P. Heinrich,et al. Evidence for the importance of a positive charge and an α‐helical structure of the C‐terminus for biological activity of human IL‐6 , 1991, FEBS letters.
[34] T. Hirano,et al. Molecular cloning and expression of an IL-6 signal transducer, gp130 , 1990, Cell.
[35] P. Heinrich,et al. The three carboxy‐terminal amino acids of human interleukin‐6 are essential for its biological activity , 1990, FEBS letters.
[36] F. D. Di Padova,et al. Structure-function analysis of human IL-6. Epitope mapping of neutralizing monoclonal antibodies with amino- and carboxyl-terminal deletion mutants. , 1990, Journal of immunology.
[37] T. Hirano,et al. Studies on the structure and regulation of the human hepatic interleukin-6 receptor. , 1990, European journal of biochemistry.
[38] T. Hirano,et al. Structure‐function analysis of human interleukin‐6 , 1990, FEBS letters.
[39] D. Wallach,et al. Soluble cytokine receptors are present in normal human urine , 1989, The Journal of experimental medicine.
[40] T. Hirano,et al. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130 , 1989, Cell.
[41] T. Taniguchi,et al. Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. , 1988, Science.
[42] S. Akira,et al. Interleukin-6 in biology and medicine. , 1993, Advances in immunology.