Hurdles in therapy with regulatory T cells
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Andrew Bushell | Anja ten Brinke | Giovanna Lombardi | Rosa Bacchetta | James A. Hutchinson | Manuela Battaglia | A. ten Brinke | J. Madrigal | S. Sánchez-Ramón | E. Geissler | M. Battaglia | M. Roncarolo | G. Lombardi | B. Sawitzki | P. Trzonkowski | A. Bushell | D. Berglund | E. Martínez-Cáceres | R. Bacchetta | S. Gregori | N. Cools | C. Hilkens | Maria Grazia Roncarolo | Nathalie Cools | Birgit Sawitzki | Edward K. Geissler | J. Hutchinson | David Berglund | Piotr Trzonkowski | Hermann Richard Bohnenkamp | Silvia Gregori | S. Marieke van Ham | Catharien Hilkens | J. Alejandro Madrigal | Natalia Marek-Trzonkowska | Eva M. Martinez-Caceres | Silvia Sanchez-Ramon | Aurore Saudemont | H. Bohnenkamp | N. Marek-Trzonkowska | A. Saudemont | S. Marieke van Ham
[1] A. Secchi,et al. Generation of Donor-specific T Regulatory Type 1 Cells From Patients on Dialysis for Cell Therapy After Kidney Transplantation , 2015, Transplantation.
[2] E. Bonifacio,et al. Adoptive transfer of allogeneic regulatory T cells into patients with chronic graft-versus-host disease. , 2015, Cytotherapy.
[3] P. Witkowski,et al. Islet cell transplant and the incorporation of Tregs , 2014, Current opinion in organ transplantation.
[4] Lydia Villa-Komaroff,et al. Purification of regulatory T cells with the use of a fully enclosed high-speed microfluidic system. , 2014, Cytotherapy.
[5] P. Harden,et al. Demethylation of the TSDR Is a Marker of Squamous Cell Carcinoma in Transplant Recipients , 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[6] James A. Hutchinson,et al. Laser Ablation–Inductively Coupled Plasma Mass Spectrometry: An Emerging Technology for Detecting Rare Cells in Tissue Sections , 2014, The Journal of Immunology.
[7] B. Falini,et al. HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse. , 2014, Blood.
[8] W. Młynarski,et al. Therapy of type 1 diabetes with CD4(+)CD25(high)CD127-regulatory T cells prolongs survival of pancreatic islets - results of one year follow-up. , 2014, Clinical immunology.
[9] R. Lechler,et al. PTU-122 A Gmp Treg Expansion Protocol Restores Treg Suppressor Function In End-stage Liver Disease; Implications For Adoptive Transfer Therapy , 2014, Gut.
[10] H. Volk,et al. Novel GMP‐Compatible Protocol Employing an Allogeneic B Cell Bank for Clonal Expansion of Allospecific Natural Regulatory T Cells , 2014, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[11] J. Wagner,et al. Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression. , 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[12] M. Roncarolo,et al. Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells , 2013, Front. Immunol..
[13] H. Volk,et al. Generation of highly effective and stable murine alloreactive Treg cells by combined anti‐CD4 mAb, TGF‐β, and RA treatment , 2013, European journal of immunology.
[14] Qizhi Tang,et al. Regulatory T-cell therapy in transplantation: moving to the clinic. , 2013, Cold Spring Harbor perspectives in medicine.
[15] A. Lares,et al. Clinical Grade Manufacturing of Human Alloantigen‐Reactive Regulatory T Cells for Use in Transplantation , 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[16] C. Meisel,et al. Standardization of whole blood immune phenotype monitoring for clinical trials: panels and methods from the ONE study , 2013, Transplantation research.
[17] E. Geissler,et al. Single cell tracking of gadolinium labeled CD4+ T cells by laser ablation inductively coupled plasma mass spectrometry. , 2013, Analytical chemistry.
[18] Graham M Lord,et al. Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation. , 2013, Clinical journal of the American Society of Nephrology : CJASN.
[19] M. Karlsson,et al. Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials , 2013, Clinical and experimental immunology.
[20] J. Wagner,et al. Adoptive transfer of umbilical cord blood-derived regulatory T cells and early viral reactivation. , 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[21] R. Lechler,et al. Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations , 2013, Haematologica.
[22] J. Siebert,et al. Clinical application of regulatory T cells in type 1 diabetes , 2013, Pediatric diabetes.
[23] Ling-jia Wang,et al. Impact of culture medium on CD4(+) CD25(high)CD127(lo/neg) Treg expansion for the purpose of clinical application. , 2013, International immunopharmacology.
[24] Michael Ringel,et al. What matters most in commercial success: first-in-class or best-in-class? , 2013, Nature Reviews Drug Discovery.
[25] Clelia Di Serio,et al. Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells , 2013, Nature Medicine.
[26] A. Rudensky,et al. Regulatory T cells: recommendations to simplify the nomenclature , 2013, Nature Immunology.
[27] P. Svingen,et al. Regulatory T cell kinetics in the peripheral blood of patients with Crohn's disease. , 2013, Human immunology.
[28] C. Loddenkemper,et al. A Converse 4-1BB and CD40 Ligand Expression Pattern Delineates Activated Regulatory T Cells (Treg) and Conventional T Cells Enabling Direct Isolation of Alloantigen-Reactive Natural Foxp3+ Treg , 2012, The Journal of Immunology.
[29] A. Foussat,et al. Safety and efficacy of antigen-specific regulatory T-cell therapy for patients with refractory Crohn's disease. , 2012, Gastroenterology.
[30] E. Geissler. The ONE Study compares cell therapy products in organ transplantation: introduction to a review series on suppressive monocyte-derived cells , 2012, Transplantation research.
[31] H. Volk,et al. Permanent CNI Treatment for Prevention of Renal Allograft Rejection in Sensitized Hosts Can Be Replaced by Regulatory T Cells , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[32] W. Młynarski,et al. Administration of CD4+CD25highCD127− Regulatory T Cells Preserves β-Cell Function in Type 1 Diabetes in Children , 2012, Diabetes Care.
[33] P. Witkowski,et al. The Time is Crucial for Ex Vivo Expansion of T Regulatory Cells for Therapy , 2011, Cell transplantation.
[34] R. Lechler,et al. In Vivo SPECT Reporter Gene Imaging of Regulatory T Cells , 2011, PloS one.
[35] M. Edinger,et al. Regulatory T cells in stem cell transplantation: strategies and first clinical experiences. , 2011, Current opinion in immunology.
[36] M. Hara,et al. Coating Human Pancreatic Islets With CD4+CD25highCD127− Regulatory T Cells as a Novel Approach for the Local Immunoprotection , 2011, Annals of surgery.
[37] M. Battaglia,et al. Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes. , 2011, Seminars in immunology.
[38] R. Lechler,et al. Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells , 2011, Science Translational Medicine.
[39] B. Falini,et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. , 2011, Blood.
[40] J. Wagner,et al. Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. , 2011, Blood.
[41] E. Hauben,et al. Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. , 2010, Blood.
[42] K. Wood,et al. In vivo Prevention of Transplant Arteriosclerosis by ex vivo Expanded Human Regulatory T Cells , 2010, Nature Medicine.
[43] J. Myśliwska,et al. First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cells. , 2009, Clinical immunology.
[44] James L Riley,et al. Human T regulatory cell therapy: take a billion or so and call me in the morning. , 2009, Immunity.
[45] J. Myśliwska,et al. Ex vivo expansion of CD4+CD25+ T regulatory cells for immunosuppressive therapy , 2009, Cytometry. Part A : the journal of the International Society for Analytical Cytology.
[46] N. Litjens,et al. Impaired immune responses and antigen-specific memory CD4+ T cells in hemodialysis patients. , 2008, Journal of the American Society of Nephrology : JASN.
[47] K. Kretschmer,et al. DNA methylation controls Foxp3 gene expression , 2008, European journal of immunology.
[48] M. Battaglia,et al. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans , 2007, Nature Reviews Immunology.
[49] D. Busch,et al. Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens. , 2007 .
[50] P. Lipsky,et al. Deficient CD4+CD25high T Regulatory Cell Function in Patients with Active Systemic Lupus Erythematosus1 , 2007, The Journal of Immunology.
[51] S. Sánchez-Ramón,et al. Interferon beta-1a therapy enhances CD4+ regulatory T-cell function: An ex vivo and in vitro longitudinal study in relapsing−remitting multiple sclerosis , 2007, Journal of Neuroimmunology.
[52] A. Akbar,et al. Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo , 2006 .
[53] D. Klatzmann,et al. Ex Vivo-Expanded CD4+CD25+ Immunoregulatory T Cells Prevent Graft-versus-Host-Disease by Inhibiting Activation/Differentiation of Pathogenic T Cells1 , 2006, The Journal of Immunology.
[54] C. Meisel,et al. Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study. , 2005, Clinical chemistry.
[55] C. Baecher-Allan,et al. Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+CD25+ T cells. , 2005, Clinical immunology.
[56] J. Serody,et al. L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. , 2004, Blood.
[57] J. Myśliwska,et al. CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction. , 2004, Clinical immunology.
[58] R. Andreesen,et al. Large scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells , 2004, Cancer Cell International.
[59] H. Waldmann,et al. Regulating the immune response to transplants. a role for CD4+ regulatory cells? , 2001, Immunity.
[60] M. Toda,et al. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.
[61] R. Gershon,et al. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. , 1970, Immunology.
[62] M. Battaglia,et al. Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications. , 2014, Current topics in microbiology and immunology.
[63] REPORT FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT AND THE COUNCIL , 2011 .
[64] D. Klatzmann,et al. Ex Vivo-Expanded CD4 CD25 Immunoregulatory T Cells Prevent Graft-versus-Host-Disease by Inhibiting Activation/ Differentiation of Pathogenic T Cells , 2005 .