Role of connexin 43 in the maintenance of spontaneous activity in the guinea pig prostate gland

BACKGROUND AND PURPOSE To investigate the role of connexin 43 in the maintenance of spontaneous activity in prostate tissue from young and old guinea pigs.

[1]  A. Gurney,et al.  Kit positive cells in the guinea pig bladder. , 2001, The Journal of urology.

[2]  R. Lang,et al.  alpha(1)-adrenoceptor modulation of spontaneous electrical waveforms in the guinea-pig prostate. , 2009, European journal of pharmacology.

[3]  R. Garfield,et al.  Studies of connexin 43 and cell-to-cell coupling in cultured human uterine smooth muscle. , 1992, American journal of obstetrics and gynecology.

[4]  P. Walsh,et al.  The development of human benign prostatic hyperplasia with age. , 1984, The Journal of urology.

[5]  R. Ruch.  The role of gap junctional intercellular communication in neoplasia. , 1994, Annals of clinical and laboratory science.

[6]  H. Coleman,et al.  Glycyrrhetinic derivatives inhibit hyperpolarization in endothelial cells of guinea pig and rat arteries. , 2002, American journal of physiology. Heart and circulatory physiology.

[7]  D. Spray,et al.  Physiology and pharmacology of gap junctions. , 1985, Annual review of physiology.

[8]  R. Ruch,et al.  Gap‐junction disassembly and connexin 43 dephosphorylation induced by 18β‐glycyrrhetinic acid , 1996, Molecular carcinogenesis.

[9]  H. Bansal,et al.  Our Modified Technique of Total Posterior Reconstruction in Open Retropubic Radical Prostatectomy , 2009, Current Urology.

[10]  J A Peters,et al.  Guide to Receptors and Channels (GRAC), 3rd edition , 2008, British journal of pharmacology.

[11]  N. Gilula,et al.  Developmental regulation and structural organization of connexins in epidermal gap junctions. , 1994, Developmental biology.

[12]  D. S. Coffey,et al.  Etiology and disease process of benign prostatic hyperplasia , 1989, The Prostate. Supplement.

[13]  R. Lang,et al.  Inositol trisphosphate‐dependent Ca2+ stores and mitochondria modulate slow wave activity arising from the smooth muscle cells of the guinea pig prostate gland , 2009, British journal of pharmacology.

[14]  N. Gilula,et al.  Multiple gap junction genes are utilized during rat skin and hair development. , 1992, Development.

[15]  S. Ward,et al.  Cellular and molecular basis for electrical rhythmicity in gastrointestinal muscles. , 1999, Annual review of physiology.

[16]  T. Roskams,et al.  Interstitial cells in the human prostate: A new therapeutic target? , 2003, The Prostate.

[17]  S. Yamada,et al.  Alpha-1 adrenoceptors in human prostate: characterization and alteration in benign prostatic hypertrophy. , 1987, The Journal of pharmacology and experimental therapeutics.

[18]  E. Daniel,et al.  Slow-wave activity in colon: role of network of submucosal interstitial cells of Cajal. , 1991, The American journal of physiology.

[19]  R. Lang,et al.  Spontaneous electrical waveforms in aging guinea pig prostates. , 2009, The Journal of urology.

[20]  B. Geiger,et al.  Molecular interactions in the submembrane plaque of cell-cell and cell-matrix adhesions. , 1995, Acta anatomica.

[21]  T. Larson.  Current treatment options for benign prostatic hyperplasia and their impact on sexual function. , 2003, Urology.

[22]  R. Lang,et al.  Spontaneous electrical activity in the prostate gland , 2006, Autonomic Neuroscience.

[23]  H. Coleman,et al.  K+ currents underlying the action of endothelium‐derived hyperpolarizing factor in guinea‐pig, rat and human blood vessels , 2001, The Journal of physiology.

[24]  R. Lang,et al.  Spontaneous slow wave and contractile activity of the guinea pig prostate. , 2002, The Journal of urology.

[25]  E. Daniel,et al.  Do gap junctions play a role in nerve transmissions as well as pacing in mouse intestine? , 2007, American journal of physiology. Gastrointestinal and liver physiology.

[26]  E. Daniel,et al.  Role of gap junctions in structural arrangements of interstitial cells of Cajal and canine ileal smooth muscle. , 1998, American journal of physiology. Gastrointestinal and liver physiology.

[27]  H. Habermann,et al.  Alterations in gap junction protein expression in human benign prostatic hyperplasia and prostate cancer. , 2001, The Journal of urology.

[28]  Guide to Receptors and Channels (GRAC), 4th edition , 2009, British journal of pharmacology.

[29]  S. Ward,et al.  Effects of the gap junction blocker glycyrrhetinic acid on gastrointestinal smooth muscle cells. , 2005, American journal of physiology. Gastrointestinal and liver physiology.

[30]  D C Spray,et al.  Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells. , 1991, Biophysical journal.

[31]  S. Ward,et al.  Morphological and physiological evidence for interstitial cell of Cajal‐like cells in the guinea pig gallbladder , 2007, The Journal of physiology.

[32]  Weixin Zhao,et al.  Increased connexin43-mediated intercellular communication in a rat model of bladder overactivity in vivo. , 2003, American journal of physiology. Regulatory, integrative and comparative physiology.

[33]  R. Lang,et al.  Prostatic Interstitial Cells in Ageing Guinea Pig Prostates , 2008, Current Urology.

[34]  P. Puri,et al.  Immunolocalization of the gap junction protein Connexin43 in the interstitial cells of Cajal in the normal and Hirschsprung's disease bowel. , 2000, Journal of pediatric surgery.