A comparison of three methods of wound closure following arthroplasty: a prospective, randomised, controlled trial.

We carried out a blinded prospective randomised controlled trial comparing 2-octylcyanoacrylate (OCA), subcuticular suture (monocryl) and skin staples for skin closure following total hip and total knee arthroplasty. We included 102 hip replacements and 85 of the knee.OCA was associated with less wound discharge in the first 24 hours for both the hip and the knee. However, with total knee replacement there was a trend for a more prolonged wound discharge with OCA. With total hip replacement there was no significant difference between the groups for either early or late complications. Closure of the wound with skin staples was significantly faster than with OCA or suture. There was no significant difference in the length of stay in hospital, Hollander wound evaluation score (cosmesis) or patient satisfaction between the groups at six weeks for either hips or knees. We consider that skin staples are the skin closure of choice for both hip and knee replacements.

[1]  P. Coulthard,et al.  Tissue adhesives for closure of sugical incisions (Review) , 2006 .

[2]  P. Coulthard,et al.  Tissue adhesives for closure of surgical incisions. , 2004, The Cochrane database of systematic reviews.

[3]  G. Rao,et al.  Clinical Experience with N-Butyl Cyanoacrylate Tissue Adhesive in Fungal Keratitis , 2003, Cornea.

[4]  K. Kawasaki,et al.  Temporary use of a customized, glued-on hard contact lens before penetrating keratoplasty for descemetocele or corneal perforation. , 2003, Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye.

[5]  R. Dinsmore,et al.  Subcuticular Closure versus Dermabond: A Prospective Randomized Trial , 2003, The American surgeon.

[6]  P. Arunachalam,et al.  A prospective comparison of tissue glue versus sutures for circumcision , 2003, Pediatric Surgery International.

[7]  R. Bhalla,et al.  Simple, painless, cosmetic closure of endaural incisions , 2003, The Journal of Laryngology & Otology.

[8]  D. Gouma,et al.  Randomized study of the effectiveness of closing laparoscopic trocar wounds with octylcyanoacrylate, adhesive papertape or poliglecaprone , 2002, The British journal of surgery.

[9]  A. Jacobsen,et al.  Comparing wound closure using tissue glue versus subcuticular suture for pediatric surgical incisions: a prospective, randomised trial , 2002, Pediatric Surgery International.

[10]  M. Bhandari,et al.  The Quality of Reporting of Randomized Trials in The Journal of Bone and Joint Surgery from 1988 through 2000 , 2002, The Journal of bone and joint surgery. American volume.

[11]  A. Singer,et al.  Closure of lacerations and incisions with octylcyanoacrylate: a multicenter randomized controlled trial. , 2002, Surgery.

[12]  N. Bromberg.  Cyanoacrylate tissue adhesive for treatment of refractory corneal ulceration. , 2002, Veterinary ophthalmology.

[13]  B. le Bail,et al.  Internal use of n-butyl 2-cyanoacrylate (Indermil) for wound closure: an experimental study. , 2001, Plastic and reconstructive surgery.

[14]  C. A. J. Shapiro,et al.  Tensile Strength of Wound Closure with Cyanoacrylate Glue , 2001, The American surgeon.

[15]  A. Shamiyeh,et al.  Prospective Randomized Blind Controlled Trial Comparing Sutures, Tape, and Octylcyanoacrylate Tissue Adhesive for Skin Closure After Phlebectomy , 2001, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[16]  L. Eichenfield,et al.  A prospective comparison of octyl cyanoacrylate tissue adhesive (dermabond) and suture for the closure of excisional wounds in children and adolescents. , 2001, Archives of dermatology.

[17]  D. Moher,et al.  The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials , 2001, Annals of Internal Medicine.

[18]  Douglas G. Altman,et al.  The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials , 2001, The Lancet.

[19]  M. Taravella,et al.  2-Octyl Cyanoacrylate Medical Adhesive in Treatment of a Corneal Perforation , 2001, Cornea.

[20]  G. Hallock.  Expanded Applications for Octyl-2-cyanoacrylate as a Tissue Adhesive , 2001, Annals of plastic surgery.

[21]  J. Kartush,et al.  Ossicular chain reconstruction using a new tissue adhesive. , 2000, The American journal of otology.

[22]  A. Singer,et al.  Octylcyanoacrylate for the treatment of contaminated partial-thickness burns in swine: a randomized controlled experiment. , 2000, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[23]  R. Goode,et al.  Efficacy of octyl-2-cyanoacrylate tissue glue in blepharoplasty. A prospective controlled study of wound-healing characteristics. , 1999, Archives of facial plastic surgery.

[24]  D. Won,et al.  An Alternate Technique to Close Neurosurgical Incisions Using Octylcyanoacrylate Tissue Adhesive , 1999, Pediatric Neurosurgery.

[25]  I. Taggart,et al.  Use of Tissue Glue in Field Situations , 1999, Journal of the Royal Army Medical Corps.

[26]  J. Gordon McComb,et al.  A Prospective Analysis of the Use of Octylcyanoacrylate Tissue Adhesive for Wound Closure in Pediatric Neurosurgery , 1999, Pediatric Neurosurgery.

[27]  P. Choong,et al.  Clinical pathways in hip and knee arthroplasty: a prospective randomised controlled study , 1999, The Medical journal of Australia.

[28]  D. Toriumi,et al.  Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery. , 1998, Plastic and reconstructive surgery.

[29]  J. Quinn,et al.  Octylcyanoacrylate tissue adhesive versus suture wound repair in a contaminated wound model. , 1997, Surgery.

[30]  V. Kratky,et al.  Cyanoacrylate Tissue Adhesive in Blepharoplasty , 1996, Ophthalmic plastic and reconstructive surgery.

[31]  J. Quinn,et al.  N-2-butylcyanoacrylate: risk of bacterial contamination with an appraisal of its antimicrobial effects. , 1995, The Journal of emergency medicine.

[32]  J E Hollander,et al.  Wound registry: development and validation. , 1995, Annals of emergency medicine.

[33]  I. Stiell,et al.  Appearance scales to measure cosmetic outcomes of healed lacerations. , 1995, The American journal of emergency medicine.

[34]  N. Niranjan,et al.  Superglue sealant for persistent leakage of cerebrospinal fluid. , 1993, Plastic and reconstructive surgery.

[35]  D. Toriumi,et al.  Variable Histotoxicity of Histoacryl When Used in a Subcutaneous Site: An Experimental Study , 1991 .

[36]  A. Shaikh,et al.  The ideal tissue adhesive in facial plastic and reconstructive surgery. , 1990, The Journal of otolaryngology.