Statin therapy and sex hormones.

[1]  F. Montecucco,et al.  Statins: Epidrugs with effects on endothelial health? , 2020, European journal of clinical investigation.

[2]  A. Sahebkar,et al.  Effects of statins on brain tumors: a review. , 2020, Seminars in cancer biology.

[3]  T. Sathyapalan,et al.  The Effect of Statins through Mast Cells in the Pathophysiology of Atherosclerosis: a Review , 2020, Current Atherosclerosis Reports.

[4]  S. Banihani Effect of statin on semen quality characteristics , 2020, Andrologia.

[5]  T. Sathyapalan,et al.  The effects of statins on microglial cells to protect against neurodegenerative disorders: A mechanistic review , 2019, BioFactors.

[6]  R. Kronmal,et al.  Association between statin use and sex hormone in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort. , 2019, The Journal of clinical endocrinology and metabolism.

[7]  F. Jing,et al.  The Effect of Statins on Levels of Dehydroepiandrosterone (DHEA) in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis , 2019, Medical science monitor : international medical journal of experimental and clinical research.

[8]  E. Hefzy,et al.  Evaluation of prolonged use of statins on the clinical and biochemical abnormalities and ovulation dysfunction in single young women with polycystic ovary syndrome , 2018, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

[9]  C. A. Stamerra,et al.  Gender Differences in Epidemiology, Pathophysiology, and Treatment of Hypertension , 2018, Current Atherosclerosis Reports.

[10]  V. Raparelli,et al.  Comparison of Clinical Outcomes Between Genders Following Antihypertensive Therapy: A Meta-Analysis. , 2017, Current medicinal chemistry.

[11]  S. Basili,et al.  Treatment and Response to Statins: Gender-related Differences. , 2017, Current medicinal chemistry.

[12]  W. Arlt,et al.  MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease , 2017, European journal of endocrinology.

[13]  P. Giorgini,et al.  Gender differences in cardiovascular prophylaxis: Focus on antiplatelet treatment , 2017, Pharmacological research.

[14]  Jiajun Zhao,et al.  SIMVASTATIN DECREASES SEX HORMONE LEVELS IN MALE RATS. , 2017, Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.

[15]  E. Joe,et al.  Role of Statin Drugs for Polycystic Ovary Syndrome , 2016, Journal of family & reproductive health.

[16]  A. Guerrero,et al.  2015 Clinical Practice Guidelines for the Management of Dyslipidemia in the Philippines - Executive Summary , 2016, ASEAN heart journal : Official journal of the ASEAN Federation of Cardiology.

[17]  M. Pencina,et al.  Impact of statin therapy on plasma adiponectin concentrations: A systematic review and meta-analysis of 43 randomized controlled trial arms. , 2016, Atherosclerosis.

[18]  A. Sahebkar,et al.  The impact of statin therapy on plasma levels of von Willebrand factor antigen , 2015, Thrombosis and Haemostasis.

[19]  B. Stricker,et al.  Use of statins is associated with lower serum total and non-sex hormone-binding globulin-bound testosterone levels in male participants of the Rotterdam Study. , 2015, European Journal of Endocrinology.

[20]  A. Sahebkar,et al.  A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations , 2015, Scientific Reports.

[21]  Jennifer G. Robinson,et al.  2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. , 2014, Circulation.

[22]  J. Laskey,et al.  Statin drugs markedly inhibit testosterone production by rat Leydig cells in vitro: implications for men. , 2014, Reproductive toxicology.

[23]  Kun-jie Wang,et al.  The role of statins in erectile dysfunction: a systematic review and meta-analysis , 2014, Asian journal of andrology.

[24]  Joel Stein,et al.  Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association. , 2014, Circulation.

[25]  Ž. Reiner Statins in the primary prevention of cardiovascular disease , 2013, Nature Reviews Cardiology.

[26]  B. Cowling,et al.  The effect of statins on testosterone in men and women, a systematic review and meta-analysis of randomized controlled trials , 2013, BMC Medicine.

[27]  B. Stuckey,et al.  Statins for women with polycystic ovary syndrome not actively trying to conceive. , 2011, The Cochrane database of systematic reviews.

[28]  M. Taskinen,et al.  ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). , 2011, Atherosclerosis.

[29]  A. Kunselman,et al.  Effects of atorvastatin on vascular function, inflammation, and androgens in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial. , 2011, Fertility and sterility.

[30]  H. Hodis,et al.  Effect of statins on estrogen and androgen levels in postmenopausal women treated with estradiol , 2011, Climacteric : the journal of the International Menopause Society.

[31]  A. Duleba,et al.  Statins inhibit growth of human theca-interstitial cells in PCOS and non-PCOS tissues independently of cholesterol availability. , 2010, The Journal of clinical endocrinology and metabolism.

[32]  E. Crawford,et al.  Effect of Statins on Serum Prostate-specific Antigen Levels. , 2010, Urology.

[33]  G. Balercia,et al.  The effect of statin therapy on testosterone levels in subjects consulting for erectile dysfunction. , 2010, The journal of sexual medicine.

[34]  Ž. Reiner,et al.  Endogenous steroid sex hormones and atherosclerosis of retinal arteries in men. , 2009, Medical science monitor : international medical journal of experimental and clinical research.

[35]  T. Erol,et al.  Does Atorvastatin Affect Androgen Levels in Men in the Era of Very-low LDL Targeting Therapy? , 2008, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

[36]  T. Travison,et al.  Do Statins Affect Androgen Levels in Men? Results from the Boston Area Community Health Survey , 2007, Cancer Epidemiology Biomarkers & Prevention.

[37]  A. Duleba,et al.  Simvastatin improves biochemical parameters in women with polycystic ovary syndrome: results of a prospective, randomized trial. , 2006, Fertility and sterility.

[38]  A. Jula,et al.  Does simvastatin affect mood and steroid hormone levels in hypercholesterolemic men? A randomized double-blind trial , 2003, Psychoneuroendocrinology.

[39]  S. Reis,et al.  Cholesterol-lowering medication, cholesterol level, and reproductive hormones in women: the Women's Ischemia Syndrome Evaluation (WISE). , 2002, The American journal of medicine.

[40]  T. Ushiroyama,et al.  Beneficial effects of pravastatin in peri- and postmenopausal hyperlipidemic women: a 5-year study on serum lipid and sex hormone levels. , 2001, Maturitas.

[41]  A. Dobs,et al.  Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia. , 2000, Metabolism: clinical and experimental.

[42]  C. Foresta,et al.  Simvastatin influences testicular steroidogenesis in human. , 1993, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[43]  H. Honjo,et al.  Menopause and hyperlipidemia: pravastatin lowers lipid levels without decreasing endogenous estrogens. , 1992, Clinical therapeutics.

[44]  A. Hofman,et al.  Determinants of disease and disability in the elderly: The Rotterdam elderly study , 1991, European Journal of Epidemiology.

[45]  T. Benraad,et al.  The HMG-CoA reductase inhibitor simvastatin suppresses human testicular testosterone synthesis in vitro by a selective inhibitory effect on 17-ketosteroid-oxidoreductase enzyme activity , 1991, The Journal of Steroid Biochemistry and Molecular Biology.

[46]  J. Goldstein,et al.  Regulation of the mevalonate pathway , 1990, Nature.

[47]  R. Grummer,et al.  A review of lipoprotein cholesterol metabolism: importance to ovarian function. , 1988, Journal of animal science.

[48]  Jonathan E. Dickerson,et al.  Supplementary webappendix , 2013 .

[49]  C. Frei,et al.  Statins and male sexual health: a retrospective cohort analysis. , 2015, The journal of sexual medicine.

[50]  C. Frei,et al.  The association of statin use and gonado-sexual function in women: a retrospective cohort analysis. , 2015, The journal of sexual medicine.

[51]  T. Urech,et al.  Gender disparities in evidence-based statin therapy in patients with cardiovascular disease. , 2015, The American journal of cardiology.

[52]  S. Stanley,et al.  Simvastatin Reduces Steroidogenesis by Inhibiting Cyp17a1 Gene Expression in Rat Ovarian Theca-Interstitial Cells1 , 2012, Biology of reproduction.

[53]  E. Kilpatrick,et al.  The effect of atorvastatin in patients with polycystic ovary syndrome: a randomized double-blind placebo-controlled study. , 2009, The Journal of clinical endocrinology and metabolism.

[54]  Prof. Dr. med. M. Böhm,et al.  Does statin therapy influence steroid hormone synthesis? , 2004, Zeitschrift für Kardiologie.

[55]  P. Lulli,et al.  Atorvastatin treatment does not affect gonadal and adrenal hormones in type 2 diabetes patients with mild to moderate hypercholesterolemia. , 2003, Journal of atherosclerosis and thrombosis.