Imaging Intramyocardial Microcirculatory Function Using Fast Computed Tomography

[1]  J. Levick,et al.  An Introduction to Cardiovascular Physiology , 2009 .

[2]  G. Heusch Coronary microembolization*1 , 2004 .

[3]  E. Ritman,et al.  Intramyocardial blood volume, perfusion and transit time in response to embolization of different sized microvessels. , 2003, Cardiovascular research.

[4]  Zeljko Bajzer,et al.  Quantification of Myocardial Microcirculatory Function with X‐ray CT , 2002, Annals of the New York Academy of Sciences.

[5]  A. Schmermund,et al.  Understanding the pathophysiology of the arterial wall: which method should we choose? Electron beam computed tomography , 2002 .

[6]  L. Lerman,et al.  Simvastatin preserves myocardial perfusion and coronary microvascular permeability in experimental hypercholesterolemia independent of lipid lowering. , 2002, Journal of the American College of Cardiology.

[7]  R. Erbel,et al.  Noninvasive assessment of microvascular function in arterial hypertension by transthoracic Doppler harmonic echocardiography. , 2002, Journal of the American College of Cardiology.

[8]  S M Grundy,et al.  Improving coronary heart disease risk assessment in asymptomatic people: role of traditional risk factors and noninvasive cardiovascular tests. , 2001, Circulation.

[9]  E L Ritman,et al.  Coronary microvascular functional reserve: quantification of long-term changes with electron-beam CT preliminary results in a porcine model. , 2001, Radiology.

[10]  A. Schmermund,et al.  Increased heterogeneity of coronary perfusion in patients with early coronary atherosclerosis. , 2001, American heart journal.

[11]  A. Schmermund,et al.  Abnormal Coronary Flow Velocity Reserve After Coronary Intervention Is Associated With Cardiac Marker Elevation , 2001, Circulation.

[12]  R. Balaban,et al.  Function, metabolic, and flow heterogeneity of the heart: the view is getting better. , 2001, Circulation research.

[13]  C. Napoli,et al.  Hypercholesterolemia impairs myocardial perfusion and permeability: role of oxidative stress and endogenous scavenging activity. , 2001, Journal of the American College of Cardiology.

[14]  A. M. Lefer,et al.  Vascular effects of HMG CoA-reductase inhibitors (statins) unrelated to cholesterol lowering: new concepts for cardiovascular disease. , 2001, Cardiovascular research.

[15]  L. Lerman,et al.  Simvastatin Preserves Coronary Endothelial Function in Hypercholesterolemia in the Absence of Lipid Lowering , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[16]  R. Erbel,et al.  Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation. , 2000, American journal of physiology. Heart and circulatory physiology.

[17]  T. Lüscher,et al.  Endothelins and Endothelin Receptor Antagonists: Therapeutic Considerations for a Novel Class of Cardiovascular Drugs , 2000, Circulation.

[18]  E. Ritman,et al.  Minimally Invasive Evaluation of Coronary Microvascular Function by Electron Beam Computed Tomography , 2000, Circulation.

[19]  G. Dell'omo,et al.  Simvastatin, capillary permeability, and acetylcholine‐mediated vasomotion in atherosclerotic, hypercholesterolemic men , 2000, Clinical pharmacology and therapeutics.

[20]  T. Lüscher,et al.  Coronary Heart Disease in Smokers: Vitamin C Restores Coronary Microcirculatory Function , 2000, Circulation.

[21]  J. Rumberger,et al.  Effects of acute and chronic angiotensin receptor blockade on myocardial vascular blood volume and perfusion in a pig model of coronary microembolization. , 2000, American journal of hypertension.

[22]  E. Topol,et al.  Recognition of the importance of embolization in atherosclerotic vascular disease. , 2000, Circulation.

[23]  Philip Greenland,et al.  Prevention Conference V Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Executive Summary , 2000 .

[24]  M. Kern,et al.  Abnormal coronary flow velocity reserve after coronary artery stenting in patients: role of relative coronary reserve to assess potential mechanisms. , 1999, Circulation.

[25]  D. Stepp,et al.  Regulation of shear stress in the canine coronary microcirculation. , 1999, Circulation.

[26]  A. Zeiher,et al.  A positive family history of premature coronary artery disease is associated with impaired endothelium-dependent coronary blood flow regulation. , 1999, Circulation.

[27]  O. Frazier,et al.  Transmyocardial revascularization with a carbon dioxide laser in patients with end-stage coronary artery disease. , 1999, The New England journal of medicine.

[28]  S. Grundy Primary prevention of coronary heart disease: integrating risk assessment with intervention. , 1999, Circulation.

[29]  T. Lyberg,et al.  Microembolization in pigs: effects on coronary blood flow and myocardial ischemic tolerance. , 1999, American journal of physiology. Heart and circulatory physiology.

[30]  M. Bell,et al.  Validation of minimally invasive measurement of myocardial perfusion using electron beam computed tomography and application in human volunteers , 1999, Heart.

[31]  E L Ritman,et al.  Measurement of in vivo myocardial microcirculatory function with electron beam CT. , 1999, Journal of computer assisted tomography.

[32]  R. Schwartz,et al.  Coronary artery apoptosis in experimental hypercholesterolemia. , 1999, Atherosclerosis.

[33]  J. Isner,et al.  Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. , 1998, Circulation.

[34]  A. Deussen,et al.  Blood flow heterogeneity in the heart , 1998, Basic Research in Cardiology.

[35]  R. D. de Winter,et al.  Immediate and long-term effect of balloon angioplasty or stent implantation on the absolute and relative coronary blood flow velocity reserve. , 1998, Circulation.

[36]  A. Heagerty,et al.  Endothelial dysfunction in human intramyocardial small arteries in atherosclerosis and hypercholesterolemia. , 1998, American journal of physiology. Heart and circulatory physiology.

[37]  C. Bloor,et al.  Exercise training in swine promotes growth of arteriolar bed and capillary angiogenesis in heart. , 1998, Journal of applied physiology.

[38]  L. Kuo,et al.  LDLs impair vasomotor function of the coronary microcirculation: role of superoxide anions. , 1998, Circulation research.

[39]  Erik L. Ritman,et al.  Temporospatial Heterogeneity of Myocardial Perfusion and Blood Volume in the Porcine Heart Wall , 1998, Annals of Biomedical Engineering.

[40]  R. Erbel,et al.  Current concepts of coronary flow reserve for clinical decision making during cardiac catheterization. , 1998, American heart journal.

[41]  R. Passariello,et al.  Magnetic resonance imaging evaluation of myocardial perfusion. , 1998, The American journal of cardiology.

[42]  A R Jayaweera,et al.  Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. , 1998, Circulation.

[43]  R. Gibbons,et al.  Coronary endothelial dysfunction in humans is associated with myocardial perfusion defects. , 1997, Circulation.

[44]  R. Schwartz,et al.  Enhanced endothelin-mediated coronary vasoconstriction and attenuated basal nitric oxide activity in experimental hypercholesterolemia. , 1997, Circulation.

[45]  M. Feldman,et al.  Myocardial contrast echocardiography can be used to quantify intramyocardial blood volume: new insights into structural mechanisms of coronary autoregulation. , 1997, Circulation.

[46]  W. Chilian Coronary microcirculation in health and disease. Summary of an NHLBI workshop. , 1997, Circulation.

[47]  A. Zeiher,et al.  Alterations of coronary blood flow and myocardial perfusion in hypercholesterolaemia. , 1996, Heart.

[48]  P. H. van der Voort,et al.  Measurement of fractional flow reserve to assess the functional severity of coronary-artery stenoses. , 1996, The New England journal of medicine.

[49]  K. Hamaoka,et al.  Coronary arterial flow-velocity dynamics in children with angiographically normal coronary arteries. , 1995, Circulation.

[50]  E L Ritman,et al.  Microvascular blood volume-to-flow relationships in porcine heart wall: whole body CT evaluation in vivo. , 1995, The American journal of physiology.

[51]  M. J. Davis,et al.  Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation. , 1995, Circulation.

[52]  Y. T. Lee,et al.  Early change of vascular permeability in hypercholesterolemic rabbits. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[53]  Ying Wang,et al.  Regional myocardial blood volume and flow: First‐pass MR imaging with polylysine‐Gd‐DTPA , 1995, Journal of magnetic resonance imaging : JMRI.

[54]  M. Winniford,et al.  Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. , 1995, Circulation.

[55]  M. Bell,et al.  Quantification of global and regional renal blood flow with electron beam computed tomography. , 1994, American journal of hypertension.

[56]  E. Ritman Myocardial Capillary Permeability to Iohexol: Evaluation with Fast X-Ray Computed Tomography , 1994, Investigative radiology.

[57]  M. Sugimachi,et al.  Reduction in serum cholesterol with pravastatin improves endothelium-dependent coronary vasomotion in patients with hypercholesterolemia. , 1994, Circulation.

[58]  E L Ritman,et al.  Measurement of renal perfusion and blood flow with fast computed tomography. , 1994, Circulation research.

[59]  James P. Martucci,et al.  Short-term cholesterol lowering decreases size and severity of perfusion abnormalities by positron emission tomography after dipyridamole in patients with coronary artery disease. A potential noninvasive marker of healing coronary endothelium. , 1994, Circulation.

[60]  R. Weiss,et al.  Quantitation of absolute regional myocardial perfusion using cine computed tomography. , 1994, Journal of the American College of Cardiology.

[61]  A. Clough,et al.  Regional transit time estimation from image residue curves , 1994, Annals of Biomedical Engineering.

[62]  R. Judd,et al.  Rapid measurements of diastolic intramyocardial vascular volume. , 1993, The American journal of physiology.

[63]  A. Nitenberg,et al.  Impairment of Coronary Vascular Reserve and ACh-Induced Coronary Vasodilation in Diabetic Patients With Angiographically Normal Coronary Arteries and Normal Left Ventricular Systolic Function , 1993, Diabetes.

[64]  M. Phelps,et al.  Influence of Age and Hemodynamics on Myocardial Blood Flow and Flow Reserve , 1993, Circulation.

[65]  F. Crea,et al.  Myocardial ischemia caused by distal coronary vasoconstriction. , 1992, The American journal of cardiology.

[66]  A. Lerman,et al.  Intact and altered endothelium in regulation of vasomotion. , 1992, Circulation.

[67]  E. vanBavel,et al.  Branching patterns in the porcine coronary arterial tree. Estimation of flow heterogeneity. , 1992, Circulation research.

[68]  E L Ritman,et al.  Dynamic intramyocardial blood volume: evaluation with a radiological opaque marker method. , 1992, The American journal of physiology.

[69]  K Rakusan,et al.  Morphometry of Human Coronary Capillaries During Normal Growth and the Effect of Age in Left Ventricular Pressure‐Overload Hypertrophy , 1992, Circulation.

[70]  L. Kuo,et al.  Pathophysiological consequences of atherosclerosis extend into the coronary microcirculation. Restoration of endothelium-dependent responses by L-arginine. , 1992, Circulation research.

[71]  E. Ritman,et al.  In Vivo Relation of Intramyocardial Blood Volume to Myocardial Perfusion: Evidence Supporting Microvascular Site for Autoregulation , 1992, Circulation.

[72]  M. Marcus,et al.  Effect of an arginine analogue on acetylcholine-induced coronary microvascular dilatation in dogs. , 1991, The American journal of physiology.

[73]  F. Klocke,et al.  First‐Pass Entry of Nonionic Contrast Agent Into the Myocardial Extravascular Space: Effects on Radiographic Estimates of Transit Time and Blood Volume , 1991, Circulation.

[74]  S. Bergmann,et al.  Noninvasive delineation of the effects of moderate aging on myocardial perfusion. , 1991, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[75]  J. Fike,et al.  Measurement of regional cerebral blood flow using ultrafast computed tomography. Theoretical aspects. , 1991, Stroke.

[76]  M. Marcus,et al.  Understanding the Coronary Circulation Through Studies at the Microvascular Level , 1990, Circulation.

[77]  J. Schrader,et al.  Control of coronary vascular tone by nitric oxide. , 1990, Circulation research.

[78]  J. Bassingthwaighte,et al.  Fractal Branchings: The Basis of Myocardial Flow Heterogeneities? , 1990, Annals of the New York Academy of Sciences.

[79]  M. Marcus,et al.  Heterogeneous changes in epimyocardial microvascular size during graded coronary stenosis. Evidence of the microvascular site for autoregulation. , 1990, Circulation research.

[80]  M. Marcus,et al.  Comparison of the Effects of Increased Myocardial Oxygen Consumption and Adenosine on the Coronary Microvascular Resistance , 1989, Circulation research.

[81]  J. Bassingthwaighte,et al.  Fractal Nature of Regional Myocardial Blood Flow Heterogeneity , 1989, Circulation research.

[82]  M. Hori,et al.  Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs. , 1989, The American journal of physiology.

[83]  J. Bassingthwaighte,et al.  Temporal fluctuations in regional myocardial flows , 1989, Pflügers Archiv.

[84]  M. Marcus,et al.  Small vessel phenomena in the coronary microcirculation: phasic intramyocardial perfusion and coronary microvascular dynamics. , 1988, Progress in cardiovascular diseases.

[85]  R. Cannon,et al.  "Microvascular angina" as a cause of chest pain with angiographically normal coronary arteries. , 1988, The American journal of cardiology.

[86]  B. Brundage,et al.  Measurement of myocardial blood flow by ultrafast computed tomography. , 1987, Circulation.

[87]  M. Lipton,et al.  Cine‐CT Measurement of Cortical Renal Blood Flow , 1987, Journal of computer assisted tomography.

[88]  D. Buss,et al.  Maturation of coronary responsiveness to exogenous adenosine in the rabbit , 1987, Basic Research in Cardiology.

[89]  R. Kronmal,et al.  Seven year survival of patients with normal or near normal coronary arteriograms: a CASS registry study. , 1986, Journal of the American College of Cardiology.

[90]  M. Lipton,et al.  Dynamic CT scanning of the normal canine liver: interpretation of time density curves resulting from an intravenous bolus injection of contrast material. , 1985, European journal of radiology.

[91]  J B Bassingthwaighte,et al.  Stability of heterogeneity of myocardial blood flow in normal awake baboons. , 1985, Circulation research.

[92]  E. Falk Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. , 1985, Circulation.

[93]  E. M. Renkin Capillary transport of macromolecules: pores and other endothelial pathways. , 1985, Journal of applied physiology.

[94]  R. Berne The role of adenosine in the regulation of coronary blood flow. , 1980, Circulation research.

[95]  L. Axel Cerebral blood flow determination by rapid-sequence computed tomography: theoretical analysis. , 1980, Radiology.

[96]  J. H. Kinsey,et al.  Physics and technical considerations in the design of the DSR: a high temporal resolution volume scanner. , 1980, AJR. American journal of roentgenology.

[97]  R. W. Redington,et al.  Cardiac Computed Tomography , 1979, Optics & Photonics.

[98]  K. Zierler Equations for Measuring Blood Flow by External Monitoring of Radioisotopes , 1965, Circulation research.

[99]  K. Zierler Theoretical Basis of Indicator‐Dilution Methods For Measuring Flow and Volume , 1962 .

[100]  Zierler Kl A simplified explanation of the theory of indicator-dilution for measurement of fluid flow and volume and other distributive phenomena. , 1958 .

[101]  K. Zierler,et al.  On the theory of the indicator-dilution method for measurement of blood flow and volume. , 1954, Journal of applied physiology.

[102]  W. F. Hamilton,et al.  STUDIES ON THE CIRCULATION , 1932 .

[103]  D. Baumgart,et al.  Neue Bildgebende Verfahren zur Darstellung der Koronararterien , 1998, Zeitschrift für Kardiologie.

[104]  H. Kempen,et al.  Effects of simvastatin on plasma lipids and apolipoproteins in familial hypercholesterolemic swine. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[105]  E. Ritman,et al.  Myocardial microcirculation as evaluated with CT. , 1995, Advances in experimental medicine and biology.

[106]  R. Beyar,et al.  Molecular and subcellular cardiology : effects of structure and function , 1995 .

[107]  K Rakusan,et al.  Changes in the microvascular network during cardiac growth, development, and aging. , 1994, Cellular & molecular biology research.

[108]  E. Ritman,et al.  Regional pulmonary perfusion estimated by high-speed volume scanning CT. , 1988, American journal of physiologic imaging.

[109]  M. Rosolowsky,et al.  Effect of hypoxia and adenosine on the microvascular reserve in the rabbit heart. , 1986, Microcirculation, endothelium, and lymphatics.

[110]  Alfred P. Fishman,et al.  The Output of the Heart , 1982 .

[111]  K. Lipscomb,et al.  Instantaneous Flow Response and Regional Distribution During Coronary Hyperemia as Measures of Coronary Flow Reserve , 1974 .

[112]  G W Hamilton,et al.  Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve. , 1974, The American journal of cardiology.

[113]  R. Berne,et al.  Coronary occlusion and embolization: effect on blood flow in adjacent arteries. , 1966, The American journal of physiology.