The TRAP/SMCC/Mediator complex and thyroid hormone receptor function

[1]  S. W. Emmons,et al.  A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene. , 2000, Genes & development.

[2]  Qianben Wang,et al.  Specific Structural Motifs Determine TRAP220 Interactions with Nuclear Hormone Receptors , 2000, Molecular and Cellular Biology.

[3]  R. Roeder,et al.  Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells. , 2000, Trends in biochemical sciences.

[4]  W. Chin,et al.  Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[5]  J. Reddy,et al.  Deletion of PBP/PPARBP, the Gene for Nuclear Receptor Coactivator Peroxisome Proliferator-activated Receptor-binding Protein, Results in Embryonic Lethality* , 2000, The Journal of Biological Chemistry.

[6]  R. Tsien,et al.  Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[7]  M. Lazar,et al.  The DRIP Complex and SRC-1/p160 Coactivators Share Similar Nuclear Receptor Binding Determinants but Constitute Functionally Distinct Complexes , 2000, Molecular and Cellular Biology.

[8]  J. Qin,et al.  The USA-derived transcriptional coactivator PC2 is a submodule of TRAP/SMCC and acts synergistically with other PCs. , 2000, Molecular cell.

[9]  R. Darnell,et al.  Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action. , 2000, Molecular cell.

[10]  M. R. Adams,et al.  Comparative genomics of the eukaryotes. , 2000, Science.

[11]  Stephen M. Mount,et al.  The genome sequence of Drosophila melanogaster. , 2000, Science.

[12]  E. Treuter,et al.  Cloning and Characterization of RAP250, a Novel Nuclear Receptor Coactivator* , 2000, The Journal of Biological Chemistry.

[13]  C. Glass,et al.  The coregulator exchange in transcriptional functions of nuclear receptors. , 2000, Genes & development.

[14]  S. Han,et al.  Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[15]  P. Meltzer,et al.  A Nuclear Factor, ASC-2, as a Cancer-amplified Transcriptional Coactivator Essential for Ligand-dependent Transactivation by Nuclear Receptors in Vivo * , 1999, The Journal of Biological Chemistry.

[16]  B. Weintraub,et al.  Ligand‐induced recruitment of a histone deacetylase in the negative‐feedback regulation of the thyrotropin β gene , 1999, The EMBO journal.

[17]  Ruben Abagyan,et al.  NRIF3 Is a Novel Coactivator Mediating Functional Specificity of Nuclear Hormone Receptors , 1999, Molecular and Cellular Biology.

[18]  Satoshi Tanaka,et al.  PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance , 1999 .

[19]  M. Garabedian,et al.  Differential regulation of glucocorticoid receptor transcriptional activation via AF‐1‐associated proteins , 1999, The EMBO journal.

[20]  K. Chien,et al.  PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development , 1999 .

[21]  R. Young,et al.  Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. , 1999, Genes & development.

[22]  R. Espinosa,et al.  Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[23]  R. Evans,et al.  Regulation of Hormone-Induced Histone Hyperacetylation and Gene Activation via Acetylation of an Acetylase , 1999, Cell.

[24]  G. Rubin,et al.  The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. , 1999, Genetics.

[25]  M. Bolin,et al.  The adenovirus E1A protein is a potent coactivator for thyroid hormone receptors. , 1999, Molecular endocrinology.

[26]  E. Lees,et al.  Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein , 1999, Nature.

[27]  D. Forrest,et al.  Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation. , 1999, Genes & development.

[28]  R. Tjian,et al.  Composite co-activator ARC mediates chromatin-directed transcriptional activation , 1999, Nature.

[29]  Paul Tempst,et al.  Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex , 1999, Nature.

[30]  R. Weiss,et al.  Mice deficient in the steroid receptor co‐activator 1 (SRC‐1) are resistant to thyroid hormone , 1999, The EMBO journal.

[31]  J. Thomsen,et al.  Competition between Thyroid Hormone Receptor-associated Protein (TRAP) 220 and Transcriptional Intermediary Factor (TIF) 2 for Binding to Nuclear Receptors , 1999, The Journal of Biological Chemistry.

[32]  R. Roeder,et al.  Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[33]  J. Qin,et al.  Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. , 1999, Molecular cell.

[34]  R. Kornberg,et al.  Conserved structures of mediator and RNA polymerase II holoenzyme. , 1999, Science.

[35]  Robert Tjian,et al.  The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1 , 1999, Nature.

[36]  U. Schibler,et al.  An RNA Polymerase II Complex Containing All Essential Initiation Factors Binds to the Activation Domain of PAR Leucine Zipper Transcription Factor Thyroid Embryonic Factor , 1999, Molecular and Cellular Biology.

[37]  J. Samarut,et al.  Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post‐natal development , 1999 .

[38]  P. Chambon,et al.  Retinoid X receptors are essential for early mouse development and placentogenesis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[39]  R. Young,et al.  RNA Polymerase II Holoenzymes and Subcomplexes* , 1998, The Journal of Biological Chemistry.

[40]  T. Willson,et al.  Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ , 1998, Nature.

[41]  D. Reinberg,et al.  NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription. , 1998, Molecular cell.

[42]  R. Kornberg,et al.  Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[43]  R. Roeder,et al.  The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[44]  E. Cook,et al.  Association of an X-chromosome dodecamer insertional variant allele with mental retardation , 1998, Molecular Psychiatry.

[45]  B. O’Malley,et al.  Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. , 1998, Science.

[46]  P. Puigserver,et al.  A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis , 1998, Cell.

[47]  F. Wondisford,et al.  Isolation and Characterization of a Novel Ligand-dependent Thyroid Hormone Receptor-coactivating Protein* , 1997, The Journal of Biological Chemistry.

[48]  M. Rao,et al.  Isolation and Characterization of PBP, a Protein That Interacts with Peroxisome Proliferator-activated Receptor* , 1997, The Journal of Biological Chemistry.

[49]  B. Haugen,et al.  Pit-1 and GATA-2 Interact and Functionally Cooperate to Activate the Thyrotropin β-Subunit Promoter* , 1997, The Journal of Biological Chemistry.

[50]  B. O’Malley,et al.  A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[51]  T. Nagaya,et al.  Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone , 1997, Molecular and cellular biology.

[52]  R. Roeder,et al.  Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Philippe Kastner,et al.  Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life? , 1995, Cell.

[54]  K. Umesono,et al.  The nuclear receptor superfamily: The second decade , 1995, Cell.

[55]  Min Han,et al.  sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction. , 1995, Genes & development.

[56]  K. Umesono,et al.  Unique response pathways are established by allosteric interactions among nuclear hormone receptors , 1995, Cell.

[57]  J. Vonesch,et al.  Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis , 1994, Cell.

[58]  R. Evans,et al.  RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. , 1994, Genes & development.

[59]  L. Swanson,et al.  TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins. , 1991, Genes & development.

[60]  Steven M. Lipkin,et al.  The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors , 1991, Cell.

[61]  J. Qin,et al.  A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation. , 1999, Molecular cell.