Identity of trypsin inhibitors isolated from bovine liver and pancreas.

A trypsin inhibitor, isolated from bovine liver, has been compared to the cat ionic trypsin inhibitor produced by bovine pancreas (Kunitz’inhibitor). The electrophoretic properties and the amino acid compositions of both inhibitors are identical. The tryptic peptides of the inhibitor isolated from liver have been purified by paper chromato-electrophoresis. The peptide map is similar to that of pancreatic inhibitor and the amino acid compositions of the 9 fragments are virtually the same in both cases.

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