Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases.
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Jürgen Hesser | Tao Wang | Holger Erfle | Chris Lawerenz | Jan Ellenberg | Steffen Remmele | Rainer Pepperkok | Beate Neumann | Julia Ritzerfeld | H. Erfle | J. Ellenberg | R. Pepperkok | J. Hesser | B. Neumann | C. Lawerenz | F. Wieland | W. Nickel | B. Brügger | Tao Wang | Britta Brügger | J. Ritzerfeld | S. Remmele | K. Temmerman | S. Wegehingel | Stella Tournaviti | J. Strating | Felix T Wieland | Walter Nickel | Koen Temmerman | Sabine Wegehingel | Stella Tournaviti | Jeroen R P M Strating
[1] H. Erfle,et al. High-throughput RNAi screening by time-lapse imaging of live human cells , 2006, Nature Methods.
[2] R. Deschenes,et al. Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases Published, JLR Papers in Press, April 1, 2006. , 2006, Journal of Lipid Research.
[3] E. Gulbins,et al. Ceramide-enriched membrane domains. , 2005, Biochimica et biophysica acta.
[4] R Eils,et al. Automated classification of mitotic phenotypes of human cells using fluorescent proteins. , 2008, Methods in cell biology.
[5] R. Yu,et al. Single-cell quantification of molecules and rates using open-source microscope-based cytometry , 2007, Nature Methods.
[6] C. Conrad,et al. Automatic identification of subcellular phenotypes on human cell arrays. , 2004, Genome research.
[7] Anne E Carpenter,et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes , 2006, Genome Biology.
[8] R. Murphy,et al. Automated subcellular location determination and high-throughput microscopy. , 2007, Developmental cell.
[9] J. Smotrys,et al. The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p , 2005, The Journal of cell biology.
[10] L. Berthiaume,et al. Functional roles for fatty acylated amino-terminal domains in subcellular localization. , 1999, Molecular biology of the cell.
[11] Meng Wang,et al. Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy , 2008, Bioinform..
[12] M. Resh. Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. , 1999, Biochimica et biophysica acta.
[13] J. Rothman,et al. Protein Sorting by Transport Vesicles , 1996, Science.
[14] M. Resh,et al. Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association. , 1997, Molecular biology of the cell.
[15] J. Parsons,et al. Src family kinases, key regulators of signal transduction , 2004, Oncogene.
[16] Jan Ellenberg,et al. Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. , 2010, Journal of structural biology.
[17] Mark C. Field,et al. Acylation-dependent Protein Export inLeishmania * , 2000, The Journal of Biological Chemistry.
[18] Kai Simons,et al. Model systems, lipid rafts, and cell membranes. , 2004, Annual review of biophysics and biomolecular structure.
[19] Holger Erfle,et al. Work Flow for Multiplexing siRNA Assays by Solid-Phase Reverse Transfection in Multiwell Plates , 2008, Journal of biomolecular screening.
[20] P. Swain,et al. Gene Regulation at the Single-Cell Level , 2005, Science.
[21] Carolin Stegmayer,et al. Direct transport across the plasma membrane of mammalian cells of Leishmania HASPB as revealed by a CHO export mutant , 2005, Journal of Cell Science.
[22] Giulio Superti-Furga,et al. RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane. , 2004, Developmental cell.
[23] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[24] M. Resh. Use of analogs and inhibitors to study the functional significance of protein palmitoylation. , 2006, Methods.
[25] Kousuke Kasahara,et al. Rapid trafficking of c-Src, a non-palmitoylated Src-family kinase, between the plasma membrane and late endosomes/lysosomes. , 2007, Experimental cell research.
[26] M. Resh. Membrane targeting of lipid modified signal transduction proteins. , 2004, Sub-cellular biochemistry.
[27] H. Erfle,et al. An RNAi screening platform to identify secretion machinery in mammalian cells. , 2007, Journal of biotechnology.
[28] T. Väisänen,et al. Modulation of the Cellular Cholesterol Level Affects Shedding of the Type XIII Collagen Ectodomain* , 2006, Journal of Biological Chemistry.
[29] C. Ungermann,et al. Analysis of DHHC Acyltransferases Implies Overlapping Substrate Specificity and a Two‐Step Reaction Mechanism , 2009, Traffic.
[30] P. Swain,et al. Stochastic Gene Expression in a Single Cell , 2002, Science.
[31] D. Brown,et al. Functions of lipid rafts in biological membranes. , 1998, Annual review of cell and developmental biology.
[32] H. Erfle,et al. Reverse transfection on cell arrays for high content screening microscopy , 2007, Nature Protocols.
[33] M. Toth,et al. Molecular Cloning and Expression of the cDNAs Encoding Human and Yeast Mevalonate Pyrophosphate Decarboxylase (*) , 1996, The Journal of Biological Chemistry.
[34] Stephen T. C. Wong,et al. Cellular Phenotype Recognition for High-Content RNA Interference Genome-Wide Screening , 2008, Journal of biomolecular screening.
[35] A. Shaw,et al. Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins , 1993, Molecular and cellular biology.
[36] Y. Hannun,et al. Acid and neutral sphingomyelinases: roles and mechanisms of regulation. , 2004, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[37] J. Rothman,et al. Mechanisms of intracellular protein transport , 1994, Nature.
[38] C. Marshall,et al. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21 ras to the plasma membrane , 1990, Cell.
[39] Holger Erfle,et al. siRNA cell arrays for high-content screening microscopy. , 2004, BioTechniques.
[40] Carolin Stegmayer,et al. Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells , 2002, Journal of Cell Science.
[41] P. Bastiaens,et al. The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins , 2010, Cell.
[42] Carolin Stegmayer,et al. SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility , 2007, Journal of Cell Science.
[43] M. Resh,et al. Inhibition of Protein Palmitoylation, Raft Localization, and T Cell Signaling by 2-Bromopalmitate and Polyunsaturated Fatty Acids* , 2000, The Journal of Biological Chemistry.
[44] D. Link,et al. Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae , 1994, The Journal of cell biology.
[45] M. Labow,et al. Cholesterol biosynthesis modulation regulates dengue viral replication. , 2009, Virology.
[46] M V Boland,et al. Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images. , 1998, Cytometry.
[47] M. Hiet,et al. Biochemical and Morphological Properties of Hepatitis C Virus Particles and Determination of Their Lipidome* , 2010, The Journal of Biological Chemistry.
[48] Hai-Shan Wu,et al. Iterative thresholding for segmentation of cells from noisy images , 2000 .
[49] R. Beck,et al. Recombinant Heptameric Coatomer Complexes: Novel Tools to Study Isoform‐Specific Functions , 2011, Traffic.
[50] F. Wieland,et al. Novel Isotypic γ/ζ Subunits Reveal Three Coatomer Complexes in Mammals , 2004, Molecular and Cellular Biology.
[51] Kousuke Kasahara,et al. Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain , 2009, Journal of Cell Science.
[52] S. Ley,et al. Palmitoylation of multiple Src-family kinases at a homologous N-terminal motif. , 1994, The Biochemical journal.
[53] R. Pepperkok,et al. Reversible Phosphorylation as a Molecular Switch to Regulate Plasma Membrane Targeting of Acylated SH4 Domain Proteins , 2009, Traffic.
[54] Scott E. Fraser,et al. Imaging in Systems Biology , 2007, Cell.
[55] M. Resh,et al. Myristylation and palmitylation of Src family members: The fats of the matter , 1994, Cell.
[56] T. Boggon,et al. Structure and regulation of Src family kinases , 2004, Oncogene.
[57] M. Frame,et al. Endosomal trafficking of Src tyrosine kinase. , 2008, Trends in cell biology.
[58] E. Ikonen,et al. Functional rafts in cell membranes , 1997, Nature.
[59] L. Berthiaume,et al. N-terminal protein acylation confers localization to cholesterol, sphingolipid-enriched membranes but not to lipid rafts/caveolae. , 2001, Molecular biology of the cell.
[60] M. Edidin. The state of lipid rafts: from model membranes to cells. , 2003, Annual review of biophysics and biomolecular structure.
[61] J. Smotrys,et al. Palmitoylation of intracellular signaling proteins: regulation and function. , 2004, Annual review of biochemistry.
[62] R. Durbin,et al. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes , 2010, Nature.
[63] R. Deschenes,et al. Palmitoylation: policing protein stability and traffic , 2007, Nature Reviews Molecular Cell Biology.