Mortality of hepatoma and cirrhosis of liver in Taiwan.

A study of mortality from hepatoma and hepatic cirrhosis was conducted in Taiwan, where their mortality rates are among the highest in the world in 1980 being 26.10 and 8.14 per 100,000 population for males and females, respectively, for hepatoma, and 33.01 and 12.90 for males and females, respectively, for cirrhosis. The secular trends of hepatoma and hepatic cirrhosis death rates have been increasing, especially in males, with consequent increase in the sex ratio. The large difference in mortality rates between males and females and the increasing trends in the sex ratio suggest that other factors besides hepatitis B virus (HBV), are involved in the aetiology of hepatoma and cirrhosis of liver.

[1]  I. Purchase,et al.  Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. , 1985, British Journal of Cancer.

[2]  T. Tung,et al.  Aflatoxin B1 in unrefined peanut oil and peanut products in Taiwan. , 1968, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association.

[3]  G. Vyas,et al.  Evidence against recessive inheritance of susceptibility to the chronic carrier state for hepatitis B antigen , 1974, Nature.

[4]  R. Beasley,et al.  Lack of an autosomal recessive genetic influence in vertical transmission of hepatitis B antigen , 1976, Nature.

[5]  P. Steiner.  Cancer of the liver and cirrhosis in trans‐Saharan Africa and the United States of America , 1960 .

[6]  Jonathan Scott Friedlaender,et al.  Hepatitis and Australia antigen: autosomal recessive inheritance of susceptibility to infection in humans. , 1969, Proceedings of the National Academy of Sciences of the United States of America.

[7]  W. Szmuness.  Hepatocellular carcinoma and the hepatitis B virus: evidence for a causal association. , 1978, Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale.

[8]  J. Hoofnagle.  Current concepts in viral hepatitis. , 1979, Arquivos de gastroenterologia.

[9]  P. Coursaget,et al.  Hepatitis B virus DNA in primary hepatocellular carcinoma tissue , 1978, Journal of medical virology.

[10]  W. Szmuness,et al.  Intrafamilial spread of asymptomatic hepatitis B. , 1975, The American journal of the medical sciences.

[11]  G. Trobozić.  [International classification of diseases, injuries and causes of death as a uniform standard in medicine]. , 1971, Narodno zdravlje.

[12]  Y. Chiang,et al.  Hepatitis B virus infection in Taiwan with reference to anti-HBc versus HBsAg and anti-HBs. , 1980, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association.

[13]  J. Sung,et al.  A seroepidemiologic study of hepatitis B virus infection in Taiwan. , 1978, Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association.