Brazilein suppresses migration and invasion of MDA-MB-231 breast cancer cells.

[1]  Sven Diederichs,et al.  The hallmarks of cancer , 2012, RNA biology.

[2]  F. Chou,et al.  Protocatechuic acid inhibits cancer cell metastasis involving the down‐regulation of Ras/Akt/NF‐κB pathway and MMP‐2 production by targeting RhoB activation , 2011, British journal of pharmacology.

[3]  Jing-Gung Chung,et al.  Down‐regulation of MMP‐2 through the p38 MAPK‐NF‐κB‐dependent pathway by aloe‐emodin leads to inhibition of nasopharyngeal carcinoma cell invasion , 2010, Molecular carcinogenesis.

[4]  Yi-Chieh Lee,et al.  Inhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway. , 2010, European journal of pharmacology.

[5]  Yeh-long Chen,et al.  Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation. , 2010, Toxicology in vitro : an international journal published in association with BIBRA.

[6]  Y. Wu,et al.  Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents. , 2010, Bioorganic & medicinal chemistry letters.

[7]  R. Meacham,et al.  p38 mitogen-activated protein kinase-driven MAPKAPK2 regulates invasion of bladder cancer by modulation of MMP-2 and MMP-9 activity. , 2010, Cancer research.

[8]  Q. Tao,et al.  Inhibition of ameloblastoma invasion in vitro and in vivo by inhibitor of metalloproteinase-2 activity. , 2009, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[9]  Chi-Tang Ho,et al.  Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells. , 2009, Carcinogenesis.

[10]  A. Jemal,et al.  Cancer Statistics, 2009 , 2009, CA: a cancer journal for clinicians.

[11]  G. Yen,et al.  Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression. , 2009, Molecular nutrition & food research.

[12]  Hyojin Cho,et al.  New pathway links from cancer‐progression determinants to gene expression of matrix metalloproteinases in breast cancer cells , 2008, Journal of cellular physiology.

[13]  Matthew S. Hayden,et al.  New regulators of NF-κB in inflammation , 2008, Nature Reviews Immunology.

[14]  S. Sheng,et al.  Metastasis and AKT activation , 2008, Cell cycle.

[15]  Y. Akao,et al.  Preconditioning by sesquiterpene lactone enhances H2O2-induced Nrf2/ARE activation. , 2008, Biochemical and biophysical research communications.

[16]  Jia Qu,et al.  Involvement of PI3K/Akt signaling pathway in hepatocyte growth factor-induced migration of uveal melanoma cells. , 2008, Investigative ophthalmology & visual science.

[17]  I. M. Lockhart 3‐Chromanols and 4‐Chromanols , 2008 .

[18]  Y. Shih,et al.  Alpha-chaconine-reduced metastasis involves a PI3K/Akt signaling pathway with downregulation of NF-kappaB in human lung adenocarcinoma A549 cells. , 2007, Journal of agricultural and food chemistry.

[19]  P. Steeg Tumor metastasis: mechanistic insights and clinical challenges , 2006, Nature Medicine.

[20]  T. Egelhoff,et al.  Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. , 2006, Cancer research.

[21]  J. Quigley,et al.  Matrix metalloproteinases and tumor metastasis , 2006, Cancer and Metastasis Reviews.

[22]  D. Han,et al.  Blocking Tumor Cell Migration and Invasion with Biphenyl Isoxazole Derivative KRIBB3, a Synthetic Molecule That Inhibits Hsp27 Phosphorylation* , 2005, Journal of Biological Chemistry.

[23]  S. Chu,et al.  Silibinin inhibits cell invasion through inactivation of both PI3K-Akt and MAPK signaling pathways. , 2005, Chemico-biological interactions.

[24]  Eun-sook Kim,et al.  TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells. , 2004, International journal of oncology.

[25]  A. Murakami,et al.  Zerumbone, a tropical ginger sesquiterpene, activates phase II drug metabolizing enzymes , 2004, FEBS letters.

[26]  D. Sliva,et al.  Signaling pathways responsible for cancer cell invasion as targets for cancer therapy. , 2004, Current cancer drug targets.

[27]  K. Reddy,et al.  Role of MAP kinase in tumor progression and invasion , 2003, Cancer and Metastasis Reviews.

[28]  S. Chakraborti,et al.  Regulation of matrix metalloproteinases: An overview , 2003, Molecular and Cellular Biochemistry.

[29]  G. Johnson,et al.  Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases , 2002, Science.

[30]  H. Koh,et al.  Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[31]  M. Duffy,et al.  Metalloproteinases: role in breast carcinogenesis, invasion and metastasis , 2000, Breast Cancer Research.

[32]  K. Knudtson,et al.  The p38 Mitogen-activated Protein Kinase Is Required for NF-κB-dependent Gene Expression , 1999, The Journal of Biological Chemistry.

[33]  J. Westermarck,et al.  Regulation of matrix metalloproteinase expression in tumor invasion , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[34]  D. Baltimore,et al.  Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB" , 1990, Nature.

[35]  A. Diplock The Chemistry of Heterocyclic Compounds: Chromenes, Chromanones and Chromones , 1978 .

[36]  R. Kizek,et al.  Matrix metalloproteinases. , 2010, Current medicinal chemistry.

[37]  S. Zheng,et al.  Brazilein inhibits survivin protein and mRNA expression and induces apoptosis in hepatocellular carcinoma HepG2 cells. , 2009, Neoplasma.

[38]  Y. Shih,et al.  Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway , 2009, Molecular and Cellular Biochemistry.

[39]  M. Monick,et al.  The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP). , 1999, The Journal of biological chemistry.

[40]  D. Baltimore,et al.  Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B. , 1990, Nature.

[41]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.