Mending Leaky Blood Vessels: The Angiopoietin-Tie2 Pathway in Sepsis
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[1] M. van Meurs,et al. Pleiotropic effects of angiopoietin-2 deficiency do not protect mice against endotoxin-induced acute kidney injury. , 2013, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[2] R. Homer,et al. Increased hyperoxia-induced lung injury in nitric oxide synthase 2 null mice is mediated via angiopoietin 2. , 2012, American journal of respiratory cell and molecular biology.
[3] N. Shapiro,et al. Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis* , 2012, Critical care medicine.
[4] M. Bauer,et al. Angiopoietin-2 Enhances Survival in Experimental Sepsis Induced by Multidrug-Resistant Pseudomonas aeruginosa , 2012, Journal of Pharmacology and Experimental Therapeutics.
[5] U. Knaus,et al. Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax , 2012, Proceedings of the National Academy of Sciences.
[6] M. Felcht,et al. Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. , 2012, The Journal of clinical investigation.
[7] Andrew Rhodes,et al. Drotrecogin alfa (activated) in adults with septic shock. , 2012, The New England journal of medicine.
[8] H. Pavenstädt,et al. The synthetic Tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis , 2011, Critical care.
[9] M. Bhasin,et al. PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice. , 2011, The Journal of clinical investigation.
[10] J. Zijlstra,et al. Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. , 2011, Cytokine.
[11] D. Dumont,et al. Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. , 2011, American journal of physiology. Lung cellular and molecular physiology.
[12] D. McDonald,et al. Angiopoietin-2-driven vascular remodeling in airway inflammation. , 2010, The American journal of pathology.
[13] 王林,et al. Acute Respiratory Distress Syndrome Network , 2010 .
[14] D. Fliser,et al. Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome , 2010, Intensive Care Medicine.
[15] K. Jang,et al. COMP-angiopoietin-1 decreases lipopolysaccharide-induced acute kidney injury. , 2009, Kidney international.
[16] B. Jeon,et al. COMP-Ang1 ameliorates leukocyte adhesion and reinforces endothelial tight junctions during endotoxemia. , 2009, Biochemical and biophysical research communications.
[17] S. Karumanchi,et al. Angiopoietin 2 Is a Partial Agonist/Antagonist of Tie2 Signaling in the Endothelium , 2009, Molecular and Cellular Biology.
[18] D. Fliser,et al. Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients , 2008, Critical care.
[19] H. Haller,et al. Circulating angiopoietin-1 and angiopoietin-2 in critically ill patients: development and clinical application of two new immunoassays , 2008, Critical care.
[20] David B Hoyt. Faculty Opinions recommendation of Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. , 2008 .
[21] D. Ingber,et al. Angiopoietin-1 Requires p190 RhoGAP to Protect against Vascular Leakage in Vivo* , 2007, Journal of Biological Chemistry.
[22] J. Sunderram,et al. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003* , 2007, Critical care medicine.
[23] G. Yancopoulos,et al. Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells , 2006, Proceedings of the National Academy of Sciences.
[24] H. Augustin,et al. Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation , 2006, Nature Medicine.
[25] D. Christiani,et al. Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans , 2006, PLoS medicine.
[26] Z. Brookes,et al. Angiopoietin-1 increases arteriolar vasoconstriction to phenylephrine during sepsis , 2005, Regulatory Peptides.
[27] B. Witzenbichler,et al. Protective Role of Angiopoietin-1 in Endotoxic Shock , 2005, Circulation.
[28] R. Henkelman,et al. Angiopoietin-1 causes reversible degradation of the portal microcirculation in mice: implications for treatment of liver disease. , 2004, The American journal of pathology.
[29] R. Schrier,et al. Acute renal failure and sepsis. , 2004, The New England journal of medicine.
[30] Patrick England,et al. A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor , 2004, EMBO reports.
[31] D. Mannino,et al. The epidemiology of sepsis in the United States from 1979 through 2000. , 2003, The New England journal of medicine.
[32] P. Campochiaro,et al. Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1. , 2002, Developmental cell.
[33] D. Annane,et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. , 2002, JAMA.
[34] E. Ivers,et al. Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock , 2001 .
[35] G. V. Berghe,et al. Intensive insulin therapy in critically ill patients. , 2001, The New England journal of medicine.
[36] G. Bernard,et al. Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis , 2001, Critical care medicine.
[37] D. Schoenfeld,et al. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. , 2000, The New England journal of medicine.
[38] N. Glazer,et al. Angiopoietin-1 protects the adult vasculature against plasma leakage , 2000, Nature Medicine.
[39] Thomas N. Sato,et al. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1. , 1999, Science.
[40] Thomas N. Sato,et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. , 1997, Science.
[41] G. Zimmerman,et al. The acute respiratory distress syndrome. , 1996, The Journal of clinical investigation.
[42] B. Bistrian,et al. Intensive insulin therapy in critically ill patients. , 2002, The New England journal of medicine.