Imaging of the heart with computed tomography

Imaging of the heart with computed tomography (CT) was already introduced in the 1980Îs and has meanwhile entered clinical routine as a consequence of the rapid evolution of CT technology during the last decade. In this review article, we give an overview on the technology and clinical performance of different CT-scanner generations used for cardiac imaging, such as Electron Beam CT (EBCT), single-slice CT und multi-detector row CT (MDCT) with 4, 16 and 64 simultaneously acquired slices. We identify the limitations of current CT-scanners, indicate potential of improvement and discuss alternative system concepts such as CT with area detectors and dual source CT (DSCT).

[1]  M. Reiser,et al.  Cardiac imaging by means of electrocardiographically gated multisection spiral CT: initial experience. , 2000, Radiology.

[2]  C. White,et al.  Non-invasive intravenous coronary angiography using electron beam tomography and multislice computed tomography , 2003, Heart.

[3]  Matthijs Oudkerk,et al.  Coronary angiography with multi-slice computed tomography , 2001, The Lancet.

[4]  Richard D. White,et al.  Do Segmented Reconstruction Algorithms for Cardiac Multi-Slice Computed Tomography Improve Image Quality? , 2003, Herz.

[5]  Borut Marincek,et al.  Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control , 2006, European Radiology.

[6]  Bernd Ohnesorge,et al.  Reproducibility and accuracy of coronary calcium measurements with multi-detector row versus electron-beam CT. , 2002, Radiology.

[7]  Gabriel P. Krestin,et al.  Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris , 2006, European Radiology.

[8]  Patrick W Serruys,et al.  Improved diagnostic accuracy with 16-row multi-slice computed tomography coronary angiography. , 2005, Journal of the American College of Cardiology.

[9]  B. Gerber,et al.  Coronary artery stenosis: direct comparison of four-section multi-detector row CT and 3D navigator MR imaging for detection--initial results. , 2005, Radiology.

[10]  Filippo Cademartiri,et al.  Patients Referred for Diagnostic Conventional Coronary Angiography High-Resolution Spiral Computed Tomography Coronary Angiography , 2005 .

[11]  Stephen Schroeder,et al.  Noninvasive detection of coronary lesions using 16-detector multislice spiral computed tomography technology: initial clinical results. , 2004, Journal of the American College of Cardiology.

[12]  K Bachmann,et al.  Curved multiplanar reconstructions for the evaluation of contrast-enhanced electron beam CT of the coronary arteries. , 1998, AJR. American journal of roentgenology.

[13]  J Simon,et al.  Image reconstruction and performance evaluation for ECG-gated spiral scanning with a 16-slice CT system. , 2003, Medical physics.

[14]  S. Kaul,et al.  Evaluating the ‘no reflow’ phenomenon with myocardial contrast echocardiography , 2006, Basic Research in Cardiology.

[15]  Herbert Bruder,et al.  Advances in cardiac imaging with 16-section CT systems. , 2003, Academic radiology.

[16]  Shinichiro Mori,et al.  Physical performance evaluation of a 256-slice CT-scanner for four-dimensional imaging. , 2004, Medical physics.

[17]  E. Perrier,et al.  Non-invasive detection of coronary artery disease in patients with left bundle branch block using 64-slice computed tomography. , 2006, Journal of the American College of Cardiology.

[18]  Konstantin Nikolaou,et al.  Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. , 2005, Journal of the American College of Cardiology.

[19]  R. Morin,et al.  Radiation dosimetry for electron beam CT. , 1994, Radiology.

[20]  M. Budoff,et al.  Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease: a multicenter study. , 1996, Circulation.

[21]  R. Morin,et al.  The technical design and performance of ultrafast computed tomography. , 1994, Radiologic clinics of North America.

[22]  R. Detrano,et al.  Quantification of coronary artery calcium using ultrafast computed tomography. , 1990, Journal of the American College of Cardiology.

[23]  Walter Heindel,et al.  Using ECG-gated multidetector CT to evaluate global left ventricular myocardial function in patients with coronary artery disease. , 2002, AJR. American journal of roentgenology.

[24]  C. McCollough,et al.  Experimental determination of section sensitivity profiles and image noise in electron beam computed tomography. , 1999, Medical physics.

[25]  W. B. Meijboom,et al.  64-Slice CT coronary angiography in patients with non-ST elevation acute coronary syndrome , 2007, Heart.

[26]  P. Serruys,et al.  Large thrombus entrapped in a patent foramen ovale of the atrial septum, which apparently “disappeared” without embolic events , 2002, Heart.

[27]  P. Serruys,et al.  Usefulness of multislice computed tomography for detecting obstructive coronary artery disease. , 2002, The American journal of cardiology.

[28]  W. Frishman,et al.  Noninvasive Coronary Angiography With Multislice Computed Tomography , 2006 .

[29]  G. Simonetti,et al.  Accuracy of thin-slice computed tomography in the detection of coronary stenoses. , 2004, European heart journal.

[30]  Simon Wildermuth,et al.  Accuracy of MSCT coronary angiography with 64-slice technology: first experience. , 2005 .

[31]  M. Oudkerk,et al.  Multidetector computed tomography-guided treatment strategy in patients with non-ST elevation acute coronary syndromes: a pilot study , 2005, European Radiology.

[32]  J. H. Kinsey,et al.  Three-dimensional imaging of heart, lungs, and circulation. , 1980, Science.

[33]  K. Stierstorfer,et al.  First performance evaluation of a dual-source CT (DSCT) system , 2006, European Radiology.

[34]  Coronary arterial calcium screening: ready for prime time? , 1998, Radiology.

[35]  R. Kim,et al.  Assessment of no-reflow regions using cardiac MRI , 2006, Basic Research in Cardiology.

[36]  J Simon,et al.  New Technical Developments in Multislice CT, Part 2: Sub-Millimeter 16-Slice Scanning and Increased Gantry Rotation Speed for Cardiac Imaging , 2002, RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin.

[37]  G. Raff,et al.  Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. , 2005, Journal of the American College of Cardiology.

[38]  W A Kalender,et al.  Electrocardiogram-correlated image reconstruction from subsecond spiral computed tomography scans of the heart. , 1998, Medical physics.

[39]  K. Stierstorfer,et al.  Image reconstruction and image quality evaluation for a 64-slice CT scanner with z-flying focal spot. , 2005, Medical physics.

[40]  Udo Hoffmann,et al.  Predictive Value of 16-Slice Multidetector Spiral Computed Tomography to Detect Significant Obstructive Coronary Artery Disease in Patients at High Risk for Coronary Artery Disease: Patient- Versus Segment-Based Analysis , 2004, Circulation.

[41]  Takayuki Obata,et al.  Properties of the prototype 256-row (cone beam) CT scanner , 2006, European Radiology.

[42]  Rainer Raupach,et al.  Dose performance of a 64-channel dual-source CT scanner. , 2007, Radiology.

[43]  K Taguchi,et al.  High temporal resolution for multislice helical computed tomography. , 2000, Medical physics.

[44]  Filippo Cademartiri,et al.  Multislice spiral computed tomography coronary angiography in patients with stable angina pectoris. , 2004, Journal of the American College of Cardiology.

[45]  K. Iwakura,et al.  Combination study of myocardial perfusion and left ventricular filling provides an excellent prediction of clinical outcomes in patients with reperfused myocardial infarction , 2006, Basic Research in Cardiology.

[46]  C. Roobottom,et al.  Highly accurate coronary angiography with submillimetre, 16 slice computed tomography , 2005, Heart.

[47]  Werner Moshage,et al.  Detection of Coronary Artery Stenoses by Contrast-Enhanced, Retrospectively Electrocardiographically-Gated, Multislice Spiral Computed Tomography , 2001, Circulation.

[48]  C. Roobottom,et al.  Multislice computed tomographic coronary angiography: experience in a UK centre. , 2003, Clinical radiology.

[49]  W. Kalender,et al.  Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. , 2006, European journal of radiology.

[50]  Werner Moshage,et al.  Noninvasive coronary angiography by retrospectively ECG-gated multislice spiral CT. , 2000 .

[51]  Heshui Shi,et al.  Noninvasive coronary angiography with multislice computed tomography. , 2005, JAMA.

[52]  B. Gerber,et al.  Diagnostic accuracy of 16-slice multidetector-row CT for detection of in-stent restenosis vs detection of stenosis in nonstented coronary arteries , 2006, European Radiology.

[53]  W A Kalender,et al.  ECG-correlated image reconstruction from subsecond multi-slice spiral CT scans of the heart. , 2000, Medical physics.

[54]  Naoki Suzuki,et al.  Real-Time Volumetric Imaging of Human Heart Without Electrocardiographic Gating by 256-Detector Row Computed Tomography: Initial Experience , 2005, Journal of computer assisted tomography.

[55]  Patrik Rogalla,et al.  Noninvasive Detection of Coronary Artery Stenoses with Multislice Computed Tomography or Magnetic Resonance Imaging , 2006, Annals of Internal Medicine.

[56]  W. Bautz,et al.  Detection of Coronary Artery Stenoses With Thin-Slice Multi-Detector Row Spiral Computed Tomography and Multiplanar Reconstruction , 2003, Circulation.

[57]  A Crispin,et al.  Coronary artery calcium measurement: agreement of multirow detector and electron beam CT. , 2001, AJR. American journal of roentgenology.

[58]  R A Robb,et al.  High speed synchronous volume computed tomography of the heart. , 1979, Radiology.

[59]  John A. Rumberger,et al.  Ultrafast Computed Tomography in Cardiac Imaging: Principles and Practice , 1992 .

[60]  Pedro A. Lemos,et al.  Reliable Noninvasive Coronary Angiography With Fast Submillimeter Multislice Spiral Computed Tomography , 2002, Circulation.

[61]  Chris A. Rogers,et al.  Multislice computed tomography coronary angiography in patients admitted with a suspected acute coronary syndrome , 2007, The International Journal of Cardiovascular Imaging.

[62]  M. Reiser,et al.  Detection of Coronary Artery Stenoses With Multislice Helical CT Angiography , 2002, Journal of computer assisted tomography.

[63]  H. Miyazaki,et al.  Development of real 4D CT with real-time reconstruction and display , 2005, IEEE Nuclear Science Symposium Conference Record, 2005.

[64]  Massimo Midiri,et al.  Improving diagnostic accuracy of MDCT coronary angiography in patients with mild heart rhythm irregularities using ECG editing. , 2006, AJR. American journal of roentgenology.

[65]  C Georg,et al.  Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography. , 2001, Journal of the American College of Cardiology.

[66]  M F Reiser,et al.  Imaging of noncalcified coronary plaques using helical CT with retrospective ECG gating. , 2000, AJR. American journal of roentgenology.

[67]  C. White,et al.  Usefulness of multislice spiral computed tomography angiography for determination of coronary artery stenoses. , 2001, The American journal of cardiology.

[68]  C Georg,et al.  Coronary arteries: retrospectively ECG-gated multi-detector row CT angiography with selective optimization of the image reconstruction window. , 2001, Radiology.

[69]  K. Engelmann,et al.  Techniques for the detection of coronary atherosclerosis: multi-detector row CT coronary angiography. , 2002, Radiology.

[70]  S. Achenbach,et al.  Detection of coronary artery stenoses using multi-detector CT with 16 x 0.75 collimation and 375 ms rotation. , 2005, European heart journal.

[71]  Patrik Rogalla,et al.  Multisegment and Halfscan Reconstruction of 16-Slice Computed Tomography for Detection of Coronary Artery Stenoses , 2004, Investigative radiology.

[72]  Stephen Schroeder,et al.  Diagnostic accuracy of noninvasive coronary imaging using 16-detector slice spiral computed tomography with 188 ms temporal resolution. , 2005, Journal of the American College of Cardiology.

[73]  C. Claussen,et al.  Diagnostic accuracy of multidetector computed tomography coronary angiography in patients with angiographically proven coronary artery disease. , 2004, Journal of the American College of Cardiology.

[74]  Konstantin Nikolaou,et al.  Dual-source CT cardiac imaging: initial experience , 2006, European Radiology.

[75]  K Stierstorfer,et al.  Performance evaluation of a 64-slice CT system with z-flying focal spot. , 2004, RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin.

[76]  C. Becker,et al.  Detection and quantification of coronary artery calcification with electron-beam and conventional CT , 1999, European Radiology.

[77]  N. Suzuki,et al.  Volumetric coronary angiography using the 256-detector row computed tomography scanner: comparison in vivo and in vitro with porcine models , 2006, Acta radiologica.