New aspects on the role of plasma lipases in lipoprotein catabolism and atherosclerosis.
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[1] M. Hayden,et al. Structural features in lipoprotein lipase necessary for the mediation of lipoprotein uptake into cells. , 1995, Journal of lipid research.
[2] T. Olivecrona,et al. Triglyceride lpases and atherosclerosis , 1995 .
[3] Sadao Takahashi,et al. Enhancement of the Binding of Triglyceride-rich Lipoproteins to the Very Low Density Lipoprotein Receptor by Apolipoprotein E and Lipoprotein Lipase (*) , 1995, The Journal of Biological Chemistry.
[4] G. Olivecrona,et al. Lipoprotein lipase enhances removal of chylomicrons and chylomicron remnants by the perfused rat liver. , 1995, Journal of lipid research.
[5] J. Gimble,et al. COOH-terminal Disruption of Lipoprotein Lipase in Mice Is Lethal in Homozygotes, but Heterozygotes Have Elevated Triglycerides and Impaired Enzyme Activity (*) , 1995, The Journal of Biological Chemistry.
[6] S. Deeb,et al. A mutation in the promoter of the lipoprotein lipase (LPL) gene in a patient with familial combined hyperlipidemia and low LPL activity. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[7] S. Humphries,et al. A common variant in the gene for lipoprotein lipase (Asp9→Asn) : functional implications and prevalence in normal and hyperlipidemic subjects , 1995 .
[8] Y. Yazaki,et al. Effects of platelet-derived growth factor on the synthesis of lipoprotein lipase in human monocyte-derived macrophages. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[9] R. Simsolo,et al. Tissue-specific Expression of Human Lipoprotein Lipase , 1995, The Journal of Biological Chemistry.
[10] R. Mahley,et al. Intravenous heparinase inhibits remnant lipoprotein clearance from the plasma and uptake by the liver: in vivo role of heparan sulfate proteoglycans. , 1995, Journal of Lipid Research.
[11] G. Renier,et al. Lipoprotein lipase synergizes with interferon gamma to induce macrophage nitric oxide synthetase mRNA expression and nitric oxide production. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[12] G. Homanics,et al. Mild Dyslipidemia in Mice following Targeted Inactivation of the Hepatic Lipase Gene (*) , 1995, The Journal of Biological Chemistry.
[13] G. Olivecrona,et al. A carboxyl-terminal fragment of lipoprotein lipase binds to the low density lipoprotein receptor-related protein and inhibits lipase-mediated uptake of lipoprotein in cells. , 1994, The Journal of biological chemistry.
[14] M. Hayden,et al. Mutagenesis in four candidate heparin binding regions (residues 279-282, 291-304, 390-393, and 439-448) and identification of residues affecting heparin binding of human lipoprotein lipase. , 1994, Journal of lipid research.
[15] J. Taylor,et al. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[16] R. Potenz,et al. Transgenic mice expressing human lipoprotein lipase driven by the mouse metallothionein promoter. A phenotype associated with increased perinatal mortality and reduced plasma very low density lipoprotein of normal size. , 1994, The Journal of biological chemistry.
[17] Y. Yazaki,et al. Induction of LDL receptor-related protein during the differentiation of monocyte-macrophages. Possible involvement in the atherosclerotic process. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[18] M. Hayden,et al. High frequency of mutations in the human lipoprotein lipase gene in pregnancy-induced chylomicronemia: possible association with apolipoprotein E2 isoform. , 1994, Journal of lipid research.
[19] J. Taylor,et al. Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture. , 1994, The Journal of biological chemistry.
[20] I. Goldberg,et al. Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins. , 1994, The Journal of biological chemistry.
[21] T. Kodama,et al. Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions. , 1994, The Journal of clinical investigation.
[22] S. Griglio,et al. Hepatic lipase may act as a ligand in the uptake of artificial chylomicron remnant-like particles by isolated rat hepatocytes. , 1994, The Biochemical journal.
[23] A. Lusis,et al. Alteration of lipid profiles in plasma of transgenic mice expressing human lipoprotein lipase. , 1994, The Journal of biological chemistry.
[24] R. Davis,et al. Lipoprotein lipase domain function. , 1994, The Journal of biological chemistry.
[25] R. Havel,et al. Role of hepatic lipase in the uptake and processing of chylomicron remnants in rat liver. , 1994, Journal of lipid research.
[26] I. Goldberg,et al. An amino-terminal fragment of apolipoprotein B binds to lipoprotein lipase and may facilitate its binding to endothelial cells. , 1994, The Journal of biological chemistry.
[27] R. Havel. Postprandial hyperlipidemia and remnant lipoproteins. , 1994, Current opinion in lipidology.
[28] J. Lalouel,et al. The carboxyl-terminal domain of lipoprotein lipase binds to the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor (LRP) and mediates binding of normal very low density lipoproteins to LRP. , 1994, The Journal of biological chemistry.
[29] M H Doolittle,et al. Molecular characterization of human hepatic lipase deficiency. In vitro expression of two naturally occurring mutations. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.
[30] A. Hamsten,et al. Postprandial lipoproteins and progression of coronary atherosclerosis. , 1994, Atherosclerosis.
[31] J. Lalouel,et al. Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis. , 1994, The Journal of biological chemistry.
[32] J. Joven,et al. Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich lipoproteins. , 1993, Journal of lipid research.
[33] M. Hayden,et al. Structure-function relationships of lipoprotein lipase: mutation analysis and mutagenesis of the loop region. , 1993, Journal of lipid research.
[34] S. Moestrup,et al. The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds lipoprotein lipase and beta-migrating very low density lipoprotein associated with the lipase. , 1993, The Journal of biological chemistry.
[35] R. Frants,et al. Low density lipoprotein receptor internalizes low density and very low density lipoproteins that are bound to heparan sulfate proteoglycans via lipoprotein lipase. , 1993, The Journal of biological chemistry.
[36] R. Hegele,et al. Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.
[37] M. Emi,et al. Binding of lipoprotein lipase to heparin. Identification of five critical residues in two distinct segments of the amino-terminal domain. , 1993, The Journal of biological chemistry.
[38] G. Bengtsson-Olivecrona,et al. Chymotryptic cleavage of lipoprotein lipase. Identification of cleavage sites and functional studies of the truncated molecule. , 1993, European journal of biochemistry.
[39] D. Brasaemle,et al. Hepatic lipase treatment of chylomicron remnants increases exposure of apolipoprotein E. , 1993, Journal of lipid research.
[40] M. Waknitz,et al. The low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor binds and mediates catabolism of bovine milk lipoprotein lipase. , 1992, The Journal of biological chemistry.
[41] H. Brewer,et al. Human lipoprotein lipase: the loop covering the catalytic site is essential for interaction with lipid substrates. , 1992, The Journal of biological chemistry.
[42] S. Eisenberg,et al. Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix. , 1992, The Journal of clinical investigation.
[43] R. Eckel,et al. Characterization of a high affinity octamer transcription factor binding site in the human lipoprotein lipase promoter. , 1992, Archives of biochemistry and biophysics.
[44] M. Schotz,et al. Hepatic and Plasma Lipases , 1992, Seminars in liver disease.
[45] R. Davis,et al. Chimeras of hepatic lipase and lipoprotein lipase. Domain localization of enzyme-specific properties. , 1992, The Journal of biological chemistry.
[46] M. Emi,et al. Missense mutations in exon 5 of the human lipoprotein lipase gene. Inactivation correlates with loss of dimerization. , 1992, The Journal of biological chemistry.
[47] Y. Arad,et al. Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages. , 1992, The Journal of clinical investigation.
[48] S. Enerbäck,et al. Characterization of the human lipoprotein lipase (LPL) promoter: evidence of two cis-regulatory regions, LP-alpha and LP-beta, of importance for the differentiation-linked induction of the LPL gene during adipogenesis , 1992, Molecular and cellular biology.
[49] M. Hayden,et al. Mapping of the epitope on lipoprotein lipase recognized by a monoclonal antibody (5D2) which inhibits lipase activity. , 1992, Biochimica et biophysica acta.
[50] M. Hayden,et al. A missense mutation Pro157 Arg in lipoprotein lipase (LPLNijmegen) resulting in loss of catalytic activity. , 1992, European journal of biochemistry.
[51] F. Faustinella,et al. Functional topology of a surface loop shielding the catalytic center in lipoprotein lipase. , 1992, Biochemistry.
[52] J. Auwerx,et al. Perturbation of developmental gene expression in rat liver by fibric acid derivatives: lipoprotein lipase and alpha-fetoprotein as models. , 1992, Development.
[53] W. Fujimoto,et al. Human lipoprotein lipase: relationship of activity, heparin affinity, and conformation as studied with monoclonal antibodies. , 1992, Journal of lipid research.
[54] S. Santamarina-Fojo. Genetic dyslipoproteinemias: role of lipoprotein lipase and apolipoprotein C-ll , 1992 .
[55] M. Huff,et al. Lipolysis is a prerequisite for lipid accumulation in HepG2 cells induced by large hypertriglyceridemic very low density lipoproteins. , 1992, The Journal of biological chemistry.
[56] M. Ferguson,et al. Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques. , 1992, The Journal of clinical investigation.
[57] J. Lalouel,et al. Lipoprotein lipase and hepatic triglyceride lipase: molecular and genetic aspects , 1992 .
[58] H. Brewer,et al. Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241. , 1992, The Journal of biological chemistry.
[59] Winston A Hide,et al. Structure and evolution of the lipase superfamily. , 1992, Journal of lipid research.
[60] C. Cambillau,et al. Effects of gene mutations in lipoprotein and hepatic lipases as interpreted by a molecular model of the pancreatic triglyceride lipase. , 1991, The Journal of biological chemistry.
[61] L. Smith,et al. Catalytic triad residue mutation (Asp156----Gly) causing familial lipoprotein lipase deficiency. Co-inheritance with a nonsense mutation (Ser447----Ter) in a Turkish family. , 1991, The Journal of biological chemistry.
[62] S. Eisenberg,et al. Lipolysis exposes unreactive endogenous apolipoprotein E-3 in human and rat plasma very low density lipoprotein. , 1991, The Journal of clinical investigation.
[63] P. Kern. Lipoprotein lipase and hepatic lipase , 1991 .
[64] M. Hayden,et al. Genetic variants affecting human lipoprotein and hepatic lipases , 1991 .
[65] M. Klein,et al. Metabolism of endothelial cell-bound lipoprotein lipase. Evidence for heparan sulfate proteoglycan-mediated internalization and recycling. , 1990, The Journal of biological chemistry.
[66] T. Olivecrona,et al. Lipoprotein lipase and hepatic lipase , 1990 .
[67] J. Kobayashi,et al. Isolation and characterization of the human hepatic lipase gene. , 1990, The Journal of biological chemistry.
[68] R. Davis,et al. Hepatic lipase: site-directed mutagenesis of a serine residue important for catalytic activity. , 1990, The Journal of biological chemistry.
[69] T. Olivecrona,et al. Lipases involved in lipoprotein metabolism , 1990 .
[70] I. Goldberg,et al. Lipoprotein ApoC-II activation of lipoprotein lipase. Modulation by apolipoprotein A-IV. , 1990, The Journal of biological chemistry.
[71] T. Kirchgessner,et al. The response of lipoprotein lipase to feeding and fasting. Evidence for posttranslational regulation. , 1990, The Journal of biological chemistry.
[72] J. Auwerx,et al. Defective enzyme protein in lipoprotein lipase deficiency , 1989, European journal of clinical investigation.
[73] J. Hokanson,et al. Large Buoyant LDL‐like Particles in Hepatic Lipase Deficiency , 1989, Arteriosclerosis.
[74] R. Eckel,et al. Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. , 1989, The New England journal of medicine.
[75] F. Karpe,et al. Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein. , 1988, Journal of lipid research.
[76] A. Chait,et al. Modification of low density lipoprotein by lipoprotein lipase or hepatic lipase induces enhanced uptake and cholesterol accumulation in cells. , 1988, The Journal of biological chemistry.
[77] G. Getz,et al. Uptake of chylomicron remnants by the liver: further evidence for the modulating role of phospholipids. , 1988, Journal of lipid research.
[78] D. Ledbetter,et al. Human hepatic lipase. Cloned cDNA sequence, restriction fragment length polymorphisms, chromosomal localization, and evolutionary relationships with lipoprotein lipase and pancreatic lipase. , 1988, The Journal of biological chemistry.
[79] R. Davis,et al. Synthesis of hepatic lipase in liver and extrahepatic tissues. , 1987, Journal of lipid research.
[80] K. Svenson,et al. The sequence of cDNA encoding lipoprotein lipase. A member of a lipase gene family. , 1987, The Journal of biological chemistry.
[81] C. Blum,et al. Association of plasma lipoproteins with postheparin lipase activities. , 1986, The Journal of clinical investigation.
[82] M. Phillips,et al. Hydrolysis of lipid monolayers and the substrate specificity of hepatic lipase. , 1986, Biochimica et biophysica acta.
[83] C. S. Wang,et al. Modulation of lipoprotein lipase activity by apolipoproteins. Effect of apolipoprotein C-III. , 1985, The Journal of clinical investigation.
[84] R. Eckel,et al. Lipoprotein lipase is produced, regulated, and functional in rat brain. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[85] T. Olivecrona,et al. Hepatic and extrahepatic uptake of intravenously injected lipoprotein lipase. , 1984, Biochimica et biophysica acta.
[86] M. Schotz,et al. Evidence for independent genetic regulation of heart and adipose lipoprotein lipase activity. , 1983, The Journal of biological chemistry.
[87] J. Little,et al. Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase. , 1982, Atherosclerosis.
[88] T. Olivecrona,et al. Binding of lipoprotein lipase to the cell surface is essential for the transmembrane transport of chylomicron cholesteryl ester. , 1982, Biochimica et biophysica acta.
[89] M. Taskinen,et al. Human postheparin plasma hepatic lipase activity against triacylglycerol and phospholipid substrates. , 1982, Clinica chimica acta; international journal of clinical chemistry.
[90] G. L. Jensen,et al. Triacylglycerol lipase, monoacylglycerol lipase and phospholipase activities of highly purified rat hepatic lipase. , 1982, Biochimica et biophysica acta.
[91] T. Olivecrona,et al. Lipoprotein lipase: some effects of activator proteins. , 1980, European journal of biochemistry.
[92] A. van Tol,et al. On the metabolic function of heparin-releasable liver lipase. , 1980, Biochemical and biophysical research communications.
[93] Ann-Margret Östlund-Lindqvist. Purification of salt resistant lipase and lipoprotein lipase from human post‐heparin plasma , 1977 .
[94] T. Olivecrona,et al. Interaction of lipoprotein lipase with heparin-Sepharose. Evaluation of conditions for affinity binding. , 1977, The Biochemical journal.
[95] A. Cooper,et al. The metabolism of chylomicron remnants by isolated perfused rat liver. , 1977, Biochimica et biophysica acta.
[96] H. Itakura,et al. The mechanism of assimilation of constituents of chylomicrons, very low density lipoproteins and remnants - a new theory. , 1975, Biochemical and biophysical research communications.
[97] M. Landt,et al. Molecular weights of nitrogenase components from Azotobacter vinelandii. , 1975, Biochemical and biophysical research communications.
[98] D. B. Zilversmit,et al. A Proposal Linking Atherogenesis to the Interaction of Endothelial Lipoprotein Lipase with Triglyceride‐Rich Lipoproteins , 1973, Circulation research.
[99] E. Korn. Clearing factor, a heparin-activated lipoprotein lipase. II. Substrate specificity and activation of coconut oil. , 1955, The Journal of biological chemistry.
[100] D. B. Zilversmit. Atherogenic nature of triglycerides, postprandial lipidemia, and triglyceride-rich remnant lipoproteins. , 1995, Clinical chemistry.
[101] A. Kessling,et al. Prevalence of alleles encoding defective lipoprotein lipase in hypertriglyceridemic patients of French Canadian descent. , 1995, Journal of lipid research.
[102] D. Carling,et al. Hepatic lipase gene is transcribed in rat adrenals into a truncated mRNA. , 1994, Journal of lipid research.
[103] M. Austin. Plasma triglyceride and coronary heart disease. , 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.
[104] Charles R.scriver. The Metabolic basis of inherited disease , 1989 .
[105] Todd G. KirchgessnerS,et al. The Sequence of cDNA Encoding Lipoprotein Lipase , 1987 .