Three-Dimensional Volumetric Reconstruction for Neuromagnetic Source Localization

Neuromagnetic measurements in conjunction with appropriate mathematical models permit the localization of centers of activity in the human brain. For large evoked response components, Monte Carlo error analyses suggest that location uncertainty due to measurement noise may be as low as 1 mm. However, in order to achieve and exploit this degree of accuracy in source localization it is necessary to improve procedures for documenting the location of sensors with respect to the head, and for locating anatomical sources which account for observed fields.