Clinical results of autologous bone augmentation harvested from the mandibular ramus prior to implant placement. An analysis of 104 cases

Background: The aim of this study was the evaluation of the clinical success and complication rates associated with autologous bone grafts harvested from the mandibular ramus for alveolar ridge augmentation and the identification of possible risk factors for graft failure. Methods: In a consecutive retrospective study 86 patients could be included. In these patients a total of 104 bone grafts from the mandibular ramus were harvested for alveolar ridge augmentation. Medical history, age of patient, smoking status, periodontal status and complications were recorded. The need for bone grafting was defined by the impossibility of installing dental implants of adequate length or diameter to fulfill prosthetic requirements, or for aesthetic reasons. The surgical outcome was evaluated concerning complications at the donor or at the recipient site, risk factors associated with the complications and graft survival. All patients were treated using a two-stage technique. In the first operation bone blocks harvested from the retromolar region were placed as lateral or vertical onlay grafts using augmentation templates and were fixed with titanium osteosynthesis screws after exposure of the deficient alveolar ridge. After a healing period of 3–5 months computed tomography scans were performed followed by virtual implant planning and the implants were inserted using guided dental implantation. Results: 97 of the 104 onlay bone grafts were successful. In only 7 patients a graft failure occurred after a postsurgical complication. No long-term nerve damage occurred. Postoperative nerve disturbances were reported by 11 patients and had temporary character only. After the healing period between 4 to 5 months, 155 implants were placed (39 in the maxilla, 116 in the mandible). A final rehabilitation with dental implants was possible in 82 of the 86 patients. Except the 7 graft failures, all recorded complications were minor complications which could be easily treated successfully without any long-term problems. Complications at the donor site were recorded in 3 patients and 17 patients experienced complications at the recipient site. Three of 7 patients with graft failure, were secondarily augmented with a new retromolar graft, harvested from the contra-lateral site and dental implants could be successfully inserted later. No association between complications and smoking habit, age of patient, jaw area, and dental situation (tooth gap or free dental arch) could be detected. Conclusions: Retromolar bone grafts are an effective and safe method for the reconstruction of small- to medium-sized alveolar defects of the maxilla and mandible prior to dental implantation and show a low graft failure rate.

[1]  S. Lundgren,et al.  Ramus or chin grafts for maxillary sinus inlay and local onlay augmentation: comparison of donor site morbidity and complications. , 2003, Clinical implant dentistry and related research.

[2]  L. Levin,et al.  Smoking and complications of onlay bone grafts and sinus lift operations. , 2004, The International journal of oral & maxillofacial implants.

[3]  L. Andersson Patient self-evaluation of intra-oral bone grafting treatment to the maxillary frontal region. , 2008, Dental traumatology : official publication of International Association for Dental Traumatology.

[4]  M. Peñarrocha,et al.  Dental implants placed simultaneously with bone grafts in horizontal defects: a clinical retrospective study with 37 patients. , 2010, The International journal of oral & maxillofacial implants.

[5]  F. Kloss,et al.  Morbidity of harvesting of chin grafts: a prospective study. , 2001, Clinical oral implants research.

[6]  E. Nkenke,et al.  Morbidity of harvesting of retromolar bone grafts: a prospective study. , 2002, Clinical oral implants research.

[7]  L. Trombelli,et al.  Cigarette smoking negatively affects healing response following flap debridement surgery. , 2001, Journal of periodontology.

[8]  E. Nkenke,et al.  The effect of load on heat production, thermal effects and expenditure of time during implant site preparation - an experimental ex vivo comparison between piezosurgery and conventional drilling. , 2014, Clinical oral implants research.

[9]  A. Vissink,et al.  Morbidity of chin bone harvesting. , 2001, Clinical oral implants research.

[10]  C. Misch,et al.  Reconstruction of maxillary alveolar defects with mandibular symphysis grafts for dental implants: a preliminary procedural report. , 1992, The International journal of oral & maxillofacial implants.

[11]  C. Misch,et al.  THE REPAIR OF LOCALIZED SEVERE RIDGE DEFECTS FOR IMPLANT PLACEMENT USING MANDIBULAR BONE GRAFTS , 1995, Implant dentistry.

[12]  Luca Cordaro,et al.  Mandibular bone harvesting for alveolar reconstruction and implant placement: subjective and objective cross-sectional evaluation of donor and recipient site up to 4 years. , 2011, Clinical oral implants research.

[13]  G. Benic,et al.  Volumetric analysis of chin and mandibular retromolar region as donor sites for cortico-cancellous bone blocks. , 2016, Clinical oral implants research.

[14]  M. Moragues,et al.  Bone microbial contamination influences autogenous grafting in sinus augmentation. , 2009, Journal of periodontology.

[15]  Ali Fakhry The mandibular retromolar area as a donor site in maxillofacial bone grafting: surgical notes. , 2011, The International journal of periodontics & restorative dentistry.

[16]  Ralf H. Gahr,et al.  GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW , 2012, GMS Interdisciplinary plastic and reconstructive surgery DGPW.

[17]  N. Gellrich,et al.  A clinical study of the outcomes and complications associated with zygomatic buttress block bone graft for limited preimplant augmentation procedures. , 2016, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[18]  H. Merten,et al.  The Multipoint Contact Plate in Fracture Treatment of the Atrophied Mandible: Animal Study and Clinical Application , 1996, Plastic and reconstructive surgery.

[19]  D. Buser,et al.  Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. , 2006, Clinical oral implants research.

[20]  F. Khoury,et al.  Mandibular bone block harvesting from the retromolar region: a 10-year prospective clinical study. , 2015, The International journal of oral & maxillofacial implants.

[21]  S. Pocock,et al.  Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): Explanation and Elaboration , 2007, PLoS medicine.

[22]  A. Vissink,et al.  Morbidity of mandibular bone harvesting: a comparative study. , 2007, The International journal of oral & maxillofacial implants.

[23]  J. Elo,et al.  Implant success in distracted bone versus autogenous bone-grafted sites. , 2009, The Journal of oral implantology.

[24]  Emeka Nkenke,et al.  Autogenous bone harvesting and grafting in advanced jaw resorption: morbidity, resorption and implant survival. , 2014, European journal of oral implantology.

[25]  S. Sindet‐Pedersen,et al.  Autogenous mandibular bone grafts and osseointegrated implants for reconstruction of the severely atrophied maxilla: a preliminary report. , 1991, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[26]  C. Hämmerle,et al.  Advances in bone augmentation to enable dental implant placement: Consensus Report of the Sixth European Workshop on Periodontology. , 2008, Journal of clinical periodontology.

[27]  M. Liberatore,et al.  Inlay-onlay grafting for three-dimensional reconstruction of the posterior atrophic maxilla with mandibular bone. , 2010, International journal of oral and maxillofacial surgery.

[28]  M. Esposito,et al.  Blocks of autogenous bone versus xenografts for the rehabilitation of atrophic jaws with dental implants: preliminary data from a pilot randomised controlled trial. , 2014, European journal of oral implantology.

[29]  M. Chiapasco,et al.  Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants. , 2006, Clinical oral implants research.