Posttraumatic stress, family functioning, and social support in survivors of childhood leukemia and their mothers and fathers.

Psychological sequelae are examined in 130 former childhood leukemia patients and 155 comparison participants and their parents. The major dependent variables are symptoms of anxiety and posttraumatic stress, family functioning, and social support. Multivariate analyses of covariance indicated significantly more posttraumatic stress symptoms in mothers and fathers of childhood leukemia survivors (p < .001) and no differences between survivors and peers. There were no significant group differences for family functioning or social support, although they were associated with anxiety and posttraumatic stress outcomes. Current child age, age at diagnosis, and months off treatment were not significantly correlated with outcome. These findings document the long-term impact of childhood cancer treatment on parents. The lack of significant differences for survivors argues for further attention to the relevance of posttraumatic stress disorder for childhood cancer survivors. The clinical implications are that psychological interventions are needed during and after cancer treatment.

[1]  D. C. Howell,et al.  Predictors of cancer progression in young adult men and women: avoidance, intrusive thoughts, and psychological symptoms. , 1994, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[2]  D. Bearison,et al.  Implications of Survival: Pediatric Oncology Patients and Their Families , 1994 .

[3]  S. Sexson,et al.  Adolescent cancer survivors. Psychosocial and familial adaptation. , 1994, Psychosomatics.

[4]  J. Pinto-Martin,et al.  Prevalence of Lead Poisoning in an Urban Cohort of Infants With High Socioeconomic Status , 1994, Clinical pediatrics.

[5]  S. Heiney,et al.  The aftermath of bone marrow transplant for parents of pediatric patients: a post-traumatic stress disorder. , 1994, Oncology nursing forum.

[6]  D. Christakis,et al.  Young adolescent cancer survivors and their parents: adjustment, learning problems, and gender , 1994 .

[7]  Dc Washington.  Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , 1994 .

[8]  A. Finch,et al.  Children exposed to disaster: II. Risk factors for the development of post-traumatic symptomatology. , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[9]  R. Mulhern,et al.  Pediatric psychooncology : psychological perspectives on children with cancer , 1994 .

[10]  D. V. Nelson,et al.  Psychometric comparability of the State−Trait Anxiety Inventory for different ethnic subpopulations , 1993 .

[11]  L. Fairbanks,et al.  Post-traumatic Stress Reactions in Children After the 1988 Armenian Earthquake , 1993, British Journal of Psychiatry.

[12]  J. A. Linney,et al.  Children with physical handicaps and their mothers: the interrelation of social support, maternal adjustment, and child adjustment. , 1992, Journal of pediatric psychology.

[13]  S. Perrin,et al.  Do childhood anxiety measures measure anxiety? , 1992, Journal of abnormal child psychology.

[14]  S. Cohen,et al.  Stress responses after pediatric bone marrow transplantation: preliminary results of a prospective longitudinal study. , 1991, Journal of the American Academy of Child and Adolescent Psychiatry.

[15]  J. E. Wraith.  The Psychosocial Effects of Bone Marrow Transplantation in Children , 1991 .

[16]  L. Perosa,et al.  Convergent and Discriminant Validity for Family Self-Report Measures , 1990 .

[17]  W. Bleyer,et al.  Acute lymphoblastic leukemia in children.Advances and prospectus , 1990, Cancer.

[18]  P. Lachenbruch.  Statistical Power Analysis for the Behavioral Sciences (2nd ed.) , 1989 .

[19]  A. Kazak,et al.  Families of chronically ill children: a systems and social-ecological model of adaptation and challenge. , 1989, Journal of consulting and clinical psychology.

[20]  C. Pot-Mees.  The psychosocial effects of bone marrow transplantation in children : proefschrift ter verkrijging van de ... , 1989 .

[21]  A. Carter,et al.  Structural and qualitative aspects of social networks in families with young chronically ill children. , 1988, Journal of pediatric psychology.

[22]  TruteBarry,et al.  Social Network Attributes of Families With Positive Adaptation to the Birth of A Developmentally Disabled Child , 1988 .

[23]  M. J. Kupst,et al.  Long-term coping with pediatric leukemia: a six-year follow-up study. , 1988, Journal of pediatric psychology.

[24]  L. Robins,et al.  Post-traumatic stress disorder in the general population. Findings of the epidemiologic catchment area survey. , 1987, The New England journal of medicine.

[25]  S Eth,et al.  Life threat and posttraumatic stress in school-age children. , 1987, Archives of general psychiatry.

[26]  J. Schwarzwald,et al.  Validation of the Impact of Event Scale for psychological sequelae of combat. , 1987, Journal of consulting and clinical psychology.

[27]  C. Reynolds,et al.  Factor analysis of the revised Children's Manifest Anxiety Scale for blacks, whites, males, and females with a national normative sample. , 1981, Journal of consulting and clinical psychology.

[28]  M. Horowitz,et al.  Impact of Event Scale: A Measure of Subjective Stress , 1979, Psychosomatic medicine.

[29]  R. D. Coddington,et al.  The significance of life events as etiologic factors in the diseases of children. II. A study of a normal population. , 1972, Journal of psychosomatic research.

[30]  C. Spielberger,et al.  Manual for the State-Trait Anxiety Inventory , 1970 .