Demonstration of Shot-noise-limited Swept Source OCT Without Balanced Detection

Optical coherence tomography (OCT) has been utilized in a rapidly growing number of clinical and scientific applications. In particular, swept source OCT (SS-OCT) has attracted many attentions due to its excellent performance. So far however, the limitations of existing photon detectors have prevented achieving shot-noise-limited sensitivity without using balanced-detection scheme in SS-OCT, even when superconducting single-photon detectors were used. Unfortunately, balanced-detection increases OCT system size and cost, as it requires many additional components to boost the laser power and maintain near ideal balanced performance across the whole optical bandwidth. Here we show for the first time that a photon detector is capable of achieving shot noise limited performance without using the balanced-detection technique in SS-OCT. We built a system using a so-called electron-injection photodetector, with a cutoff-wavelength of 1700 nm. Our system achieves a shot-noise-limited sensitivity of about −105 dB at a reference laser power of ~350 nW, which is more than 30 times lower laser power compared with the best-reported results. The high sensitivity of the electron-injection detector allows utilization of micron-scale tunable laser sources (e.g. VCSEL) and eliminates the need for fiber amplifiers and highly precise couplers, which are an essential part of the conventional SS-OCT systems.

[1]  G. Aguilar,et al.  Use of optical coherence tomography to monitor biological tissue freezing during cryosurgery. , 2004, Journal of biomedical optics.

[2]  C. Baird,et al.  The pilot study. , 2000, Orthopedic nursing.

[3]  Weijian Yang,et al.  Laser optomechanics , 2015, Scientific Reports.

[4]  E. Semenova,et al.  1060-nm Tunable Monolithic High Index Contrast Subwavelength Grating VCSEL , 2013, IEEE Photonics Technology Letters.

[5]  J. Duker,et al.  Ultrahigh speed 1050nm swept source/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second. , 2010, Optics express.

[6]  A. Podoleanu Unbalanced versus balanced operation in an optical coherence tomography system. , 2000, Applied optics.

[7]  Martin F. Kraus,et al.  Handheld ultrahigh speed swept source optical coherence tomography instrument using a MEMS scanning mirror. , 2013, Biomedical optics express.

[8]  Vala Fathipour,et al.  Impact of three-dimensional geometry on the performance of isolated electron-injection infrared detectors , 2015 .

[9]  J. Izatt,et al.  Optimal interferometer designs for optical coherence tomography. , 1999, Optics letters.

[10]  Bo Liu,et al.  Optimal spectral reshaping for resolution improvement in optical coherence tomography. , 2006, Optics express.

[11]  J. Fujimoto,et al.  Wideband Electrically Pumped 1050-nm MEMS-Tunable VCSEL for Ophthalmic Imaging , 2015, Journal of Lightwave Technology.

[12]  Changhuei Yang,et al.  Instantaneous complex conjugate resolved spectral domain and swept-source OCT using 3x3 fiber couplers. , 2005, Optics express.

[13]  A. Al-Mujaini,et al.  Optical coherence tomography: clinical applications in medical practice. , 2013, Oman medical journal.

[14]  Vijaysekhar Jayaraman,et al.  MEMS tunable VCSEL light source for ultrahigh speed 60kHz - 1MHz axial scan rate and long range centimeter class OCT imaging , 2012, Photonics West - Biomedical Optics.

[15]  J. Fujimoto,et al.  Optical biopsy and imaging using optical coherence tomography , 1995, Nature Medicine.

[16]  J. Fujimoto,et al.  Optical coherence tomography: an emerging technology for biomedical imaging and optical biopsy. , 2000, Neoplasia.

[17]  S. Yun,et al.  High-speed optical frequency-domain imaging. , 2003, Optics express.

[18]  Photon-counting optical coherence-domain reflectometry using superconducting single-photon detectors. , 2008, Optics express.

[19]  D. D. de Bruin,et al.  Spectrally balanced detection for optical frequency domain imaging. , 2007, Optics express.

[20]  D. P. Worland,et al.  Long-Wavelength VCSEL Using High-Contrast Grating , 2013, IEEE Journal of Selected Topics in Quantum Electronics.

[21]  L L Otis,et al.  Optical coherence tomography: a new imaging technology for dentistry. , 2000, Journal of the American Dental Association.

[22]  Jeehyun Kim,et al.  Optical coherence tomography for advanced screening in the primary care office , 2014, Journal of biophotonics.

[23]  Suhwan Kim,et al.  Non-Destructive Inspection Methods for LEDs Using Real-Time Displaying Optical Coherence Tomography , 2012, Sensors.

[24]  Ruikang K. Wang,et al.  Wide-field optical coherence tomography based microangiography for retinal imaging , 2016, Scientific Reports.

[25]  D. Pacifici,et al.  Measuring subwavelength spatial coherence with plasmonic interferometry , 2016, Nature Photonics.

[26]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.

[27]  J. Fujimoto,et al.  High-precision, high-accuracy ultralong-range swept-source optical coherence tomography using vertical cavity surface emitting laser light source. , 2013, Optics letters.

[28]  Wen-Chuan Kuo,et al.  Balanced detection for spectral domain optical coherence tomography. , 2013, Optics express.

[29]  J. R. Scotti,et al.  Available From , 1973 .

[30]  Vala Fathipour,et al.  Isolated Electron Injection Detectors With High Gain and Record Low Dark Current at Telecom Wavelength , 2014, IEEE Journal of Selected Topics in Quantum Electronics.

[31]  J. Fujimoto Optical coherence tomography for ultrahigh resolution in vivo imaging , 2003, Nature Biotechnology.

[32]  Vala Fathipour,et al.  Analytical modeling and numerical simulation of the short-wave infrared electron-injection detectors , 2016 .

[33]  Tiegen Liu,et al.  Measurements of the thermal coefficient of optical attenuation at different depth regions of in vivo human skins using optical coherence tomography: a pilot study. , 2015, Biomedical optics express.

[34]  A. Low,et al.  Technology Insight: optical coherence tomography—current status and future development , 2006, Nature Clinical Practice Cardiovascular Medicine.

[35]  V. Jayaraman,et al.  High-speed ultra-broad tuning MEMS-VCSELs for imaging and spectroscopy , 2013, Microtechnologies for the New Millennium.

[36]  Hooman Mohseni,et al.  Sub-Poissonian shot noise of a high internal gain injection photon detector. , 2008, Optics express.

[37]  Chen D. Lu,et al.  Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers , 2012, Biomedical optics express.

[38]  O. Matoba,et al.  High-speed cross-sectional imaging of valuable documents using common-path swept-source optical coherence tomography. , 2011, Applied optics.

[39]  Daiva Paulaviciute-Baikstiene,et al.  Clinical Applications in Medical Practice , 2019, Biophysical Properties in Glaucoma.

[40]  J. Fujimoto,et al.  Optical coherence tomography using a frequency-tunable optical source. , 1997, Optics letters.

[41]  Hooman Mohseni,et al.  A photon detector with very high gain at low bias and at room temperature , 2007 .

[42]  Hobin Kang,et al.  Nondestructive Assessment of Early Tooth Demineralization Using Cross-Polarization Optical Coherence Tomography , 2010, IEEE Journal of Selected Topics in Quantum Electronics.